WO2009067640A3 - Delivery and assessment system for the automated manufacturing of high performance nanofluidic separation devices - Google Patents

Delivery and assessment system for the automated manufacturing of high performance nanofluidic separation devices Download PDF

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Publication number
WO2009067640A3
WO2009067640A3 PCT/US2008/084272 US2008084272W WO2009067640A3 WO 2009067640 A3 WO2009067640 A3 WO 2009067640A3 US 2008084272 W US2008084272 W US 2008084272W WO 2009067640 A3 WO2009067640 A3 WO 2009067640A3
Authority
WO
WIPO (PCT)
Prior art keywords
column
packed bed
assessment system
automated
delivery
Prior art date
Application number
PCT/US2008/084272
Other languages
French (fr)
Other versions
WO2009067640A2 (en
Inventor
Pelt Collen K Van
Original Assignee
Corsolutions Llc
Pelt Collen K Van
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Corsolutions Llc, Pelt Collen K Van filed Critical Corsolutions Llc
Publication of WO2009067640A2 publication Critical patent/WO2009067640A2/en
Publication of WO2009067640A3 publication Critical patent/WO2009067640A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/50—Conditioning of the sorbent material or stationary liquid
    • G01N30/56—Packing methods or coating methods

Abstract

A multi-column packing system and packed bed assessment system for producing small bore LC columns of superior quality, improved column-to-column reproducibility, and lower cost than current commercially available columns. The process utilizes an automated multi-column packing system with an integrated sensor that detects when the slurry-packed bed has reached the desired length. The optical packed bed assessment system examines the packed bed within the column and detects any packing inconsistencies or voids within the column. The multi-column packing system makes automated connections to tubes via an automated compression mechanism.
PCT/US2008/084272 2007-11-21 2008-11-21 Delivery and assessment system for the automated manufacturing of high performance nanofluidic separation devices WO2009067640A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US98958107P 2007-11-21 2007-11-21
US60/989,581 2007-11-21

Publications (2)

Publication Number Publication Date
WO2009067640A2 WO2009067640A2 (en) 2009-05-28
WO2009067640A3 true WO2009067640A3 (en) 2009-08-06

Family

ID=40668092

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/084272 WO2009067640A2 (en) 2007-11-21 2008-11-21 Delivery and assessment system for the automated manufacturing of high performance nanofluidic separation devices

Country Status (2)

Country Link
US (1) US8163177B2 (en)
WO (1) WO2009067640A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5438034B2 (en) * 2008-02-21 2014-03-12 オールテック・アソシエイツ・インコーポレーテッド Column packing apparatus and method of manufacturing and using the same
US8357301B2 (en) * 2009-06-24 2013-01-22 Hoffmann-La Roche, Inc. Chromatography equipment characterization
US20110138749A1 (en) * 2009-12-15 2011-06-16 Donald Chow System and method for manufacturing a tubular container with opening and closing means
JP5320416B2 (en) * 2011-01-26 2013-10-23 株式会社日立ハイテクノロジーズ Electrophoresis device, capillary array, and capillary unit
US20150241389A1 (en) * 2014-02-24 2015-08-27 ProteinSimple Multi-capillary cartridge for capillary electrophoresis
CN104865328B (en) * 2015-05-26 2016-09-28 中国人民解放军军事医学科学院放射与辐射医学研究所 A kind of device of multichannel homogenate filling capillary chromatographic column
CN104931636B (en) * 2015-06-23 2016-06-22 上海通微分析技术有限公司 Based on detector on the ultraviolet capillary column of CCD
US10254256B2 (en) * 2015-10-01 2019-04-09 Thermo Hypersil-Keystone Llc Method of packing chromatographic columns, packed chromatographic columns for use at high pressures and uses thereof
US20220155267A1 (en) * 2020-11-18 2022-05-19 Thermo Finnigan Llc Packed Tip Electrospray Emitter

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030026740A1 (en) * 2001-08-06 2003-02-06 Staats Sau Lan Tang Microfluidic devices
KR20040009553A (en) * 2002-07-24 2004-01-31 대한약품공업 주식회사 Liquid Injection Divice into Empty Ampules and Method of Liquid injection Using the Device, Ampule Filled with Liquid by the Device
US20050242017A1 (en) * 2004-04-15 2005-11-03 Staats Sau Lan T Microfluidic devices for liquid chromatography and mass spectrometry

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6401555B1 (en) * 1999-06-14 2002-06-11 James R. Bowers Tube packing extension assembly for use in high temperature gas flow sensing elements and the like
CN100528363C (en) * 2002-02-13 2009-08-19 安捷伦科技有限公司 Microfluidic separation column devices and preparation method thereof
US7261812B1 (en) * 2002-02-13 2007-08-28 Nanostream, Inc. Multi-column separation devices and methods
US20050032238A1 (en) * 2003-08-07 2005-02-10 Nanostream, Inc. Vented microfluidic separation devices and methods

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030026740A1 (en) * 2001-08-06 2003-02-06 Staats Sau Lan Tang Microfluidic devices
KR20040009553A (en) * 2002-07-24 2004-01-31 대한약품공업 주식회사 Liquid Injection Divice into Empty Ampules and Method of Liquid injection Using the Device, Ampule Filled with Liquid by the Device
US20050242017A1 (en) * 2004-04-15 2005-11-03 Staats Sau Lan T Microfluidic devices for liquid chromatography and mass spectrometry

Also Published As

Publication number Publication date
WO2009067640A2 (en) 2009-05-28
US20090151808A1 (en) 2009-06-18
US8163177B2 (en) 2012-04-24

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