WO2009076413A3 - Methods, devices and compositions for controlled drug delivery to injured myocardium - Google Patents
Methods, devices and compositions for controlled drug delivery to injured myocardium Download PDFInfo
- Publication number
- WO2009076413A3 WO2009076413A3 PCT/US2008/086185 US2008086185W WO2009076413A3 WO 2009076413 A3 WO2009076413 A3 WO 2009076413A3 US 2008086185 W US2008086185 W US 2008086185W WO 2009076413 A3 WO2009076413 A3 WO 2009076413A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- devices
- compositions
- methods
- drug delivery
- controlled drug
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
- A61L29/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/602—Type of release, e.g. controlled, sustained, slow
- A61L2300/604—Biodegradation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/62—Encapsulated active agents, e.g. emulsified droplets
- A61L2300/622—Microcapsules
Abstract
A method for modulating remodeling of an infarct region of a myocardium, the method including the controlled local delivery of therapeutic agent(s) employing microparticles as a carrier, and devices and compositions relating thereto.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP08859170.6A EP2231213B1 (en) | 2007-12-12 | 2008-12-10 | Methods, devices and compositions for controlled drug delivery to injured myocardium |
JP2010538114A JP2011505984A (en) | 2007-12-12 | 2008-12-10 | Method for controlled drug delivery to the injured myocardium |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/954,408 US8551072B2 (en) | 2007-12-12 | 2007-12-12 | Methods, devices and compositions for controlled drug delivery to injured myocardium |
US11/954,408 | 2007-12-12 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2009076413A2 WO2009076413A2 (en) | 2009-06-18 |
WO2009076413A3 true WO2009076413A3 (en) | 2009-08-06 |
Family
ID=40352434
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2008/086185 WO2009076413A2 (en) | 2007-12-12 | 2008-12-10 | Methods, devices and compositions for controlled drug delivery to injured myocardium |
Country Status (4)
Country | Link |
---|---|
US (1) | US8551072B2 (en) |
EP (1) | EP2231213B1 (en) |
JP (1) | JP2011505984A (en) |
WO (1) | WO2009076413A2 (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10155099B2 (en) | 2009-09-21 | 2018-12-18 | Cook Regentec Llc | Method for infusing stem cells |
US10058675B2 (en) | 2009-09-21 | 2018-08-28 | Cook Regentec Llc | Infusion catheter tip for biologics with reinforced external balloon valve |
US8647311B2 (en) * | 2009-09-21 | 2014-02-11 | Translational Biologic Infusion Catheter, Llc | Biologics infusion system |
US20130330412A1 (en) * | 2010-12-10 | 2013-12-12 | The Johns Hopkins University | Smart polymeric nanoparticles which overcome multidrug resistance to cancer therapeutics and treatment-related systemic toxicity |
US20220387674A1 (en) * | 2019-07-11 | 2022-12-08 | The University Of Tokyo | Medical instrument |
CN114949551A (en) * | 2021-06-01 | 2022-08-30 | 深圳市本尚医疗科技有限公司 | Porous balloon catheter system and method of use |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002024248A1 (en) * | 2000-09-22 | 2002-03-28 | Kensey Nash Corporation | Systems and methods for delivering beneficial agents into targeted tissue of a living being |
US20060280858A1 (en) * | 2001-01-05 | 2006-12-14 | Lyudmila Kokish | Balloon catheter for delivering therapeutic agents |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5740808A (en) * | 1996-10-28 | 1998-04-21 | Ep Technologies, Inc | Systems and methods for guilding diagnostic or therapeutic devices in interior tissue regions |
WO1998017318A1 (en) * | 1996-10-19 | 1998-04-30 | Quadrant Healthcare (Uk) Limited | Use of hollow microcapsules in diagnosis and therapy |
US6042820A (en) * | 1996-12-20 | 2000-03-28 | Connaught Laboratories Limited | Biodegradable copolymer containing α-hydroxy acid and α-amino acid units |
WO1999016500A2 (en) * | 1997-10-01 | 1999-04-08 | Medtronic Ave, Inc. | Drug delivery and gene therapy delivery system |
GB9727102D0 (en) * | 1997-12-22 | 1998-02-25 | Andaris Ltd | Microparticles and their therapeutic use |
US6451349B1 (en) * | 1998-08-19 | 2002-09-17 | Quadrant Healthcare (Uk) Limited | Spray-drying process for the preparation of microparticles |
US7195780B2 (en) * | 2002-10-21 | 2007-03-27 | University Of Florida | Nanoparticle delivery system |
US6899731B2 (en) * | 1999-12-30 | 2005-05-31 | Boston Scientific Scimed, Inc. | Controlled delivery of therapeutic agents by insertable medical devices |
US20060177416A1 (en) * | 2003-10-14 | 2006-08-10 | Medivas, Llc | Polymer particle delivery compositions and methods of use |
US6545097B2 (en) * | 2000-12-12 | 2003-04-08 | Scimed Life Systems, Inc. | Drug delivery compositions and medical devices containing block copolymer |
US20020114843A1 (en) * | 2000-12-27 | 2002-08-22 | Ramstack J. Michael | Preparation of microparticles having improved flowability |
US7014654B2 (en) * | 2001-11-30 | 2006-03-21 | Scimed Life Systems, Inc. | Stent designed for the delivery of therapeutic substance or other agents |
US6720008B2 (en) * | 2002-01-22 | 2004-04-13 | Pr Pharmaceuticals, Inc. | Composition and method for the encapsulation of water-soluble molecules into nanoparticles |
US7105175B2 (en) * | 2002-06-19 | 2006-09-12 | Boston Scientific Scimed, Inc. | Implantable or insertable medical devices for controlled delivery of a therapeutic agent |
US7101566B2 (en) * | 2002-06-28 | 2006-09-05 | Ethicon, Inc. | Polymer coated microparticles for sustained release |
EP1610752B1 (en) * | 2003-01-31 | 2013-01-02 | Boston Scientific Limited | Localized drug delivery using drug-loaded nanocapsules and implantable device coated with the same |
US8383158B2 (en) * | 2003-04-15 | 2013-02-26 | Abbott Cardiovascular Systems Inc. | Methods and compositions to treat myocardial conditions |
US7288084B2 (en) * | 2003-04-28 | 2007-10-30 | Boston Scientific Scimed, Inc. | Drug-loaded medical device |
US20050175709A1 (en) * | 2003-12-11 | 2005-08-11 | Baty Ace M.Iii | Therapeutic microparticles |
US20050220853A1 (en) * | 2004-04-02 | 2005-10-06 | Kinh-Luan Dao | Controlled delivery of therapeutic agents from medical articles |
NZ553149A (en) * | 2004-08-12 | 2010-01-29 | Quest Pharmaceutical Services | Use of inositol hexaphosphate or inositol hexasulphate to complex biologically active compounds for the preparation of controlled release pharmaceutical compositions |
WO2006039369A1 (en) * | 2004-09-29 | 2006-04-13 | Alza Corporation | Microparticles and nanoparticles containing a lipopolymer |
AU2006239154A1 (en) * | 2005-04-28 | 2006-11-02 | Ventana Medical Systems, Inc | Nanoparticle conjugates |
US8216209B2 (en) * | 2007-05-31 | 2012-07-10 | Abbott Cardiovascular Systems Inc. | Method and apparatus for delivering an agent to a kidney |
-
2007
- 2007-12-12 US US11/954,408 patent/US8551072B2/en not_active Expired - Fee Related
-
2008
- 2008-12-10 JP JP2010538114A patent/JP2011505984A/en active Pending
- 2008-12-10 WO PCT/US2008/086185 patent/WO2009076413A2/en active Application Filing
- 2008-12-10 EP EP08859170.6A patent/EP2231213B1/en not_active Not-in-force
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002024248A1 (en) * | 2000-09-22 | 2002-03-28 | Kensey Nash Corporation | Systems and methods for delivering beneficial agents into targeted tissue of a living being |
US20060280858A1 (en) * | 2001-01-05 | 2006-12-14 | Lyudmila Kokish | Balloon catheter for delivering therapeutic agents |
Non-Patent Citations (2)
Title |
---|
GRADUS-PIZLO IRMINA ET AL: "Local delivery of biodegradable microparticles containing colchicine or a colchicine analogue: Effects on restenosis and implications for catheter-based drug delivery", 1995, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, VOL. 26, NR. 6, PAGE(S) 1549-1557, ISSN: 0735-1097, XP002516537 * |
WILENSKY R L ET AL: "Methods and devices for local drug delivery in coronary and peripheral arteries", TRENDS IN CARDIOVASCULAR MEDICINE, ELSEVIER SCIENCE, NEW YORK, NY, US, vol. 3, no. 5, 1 September 1993 (1993-09-01), pages 163 - 170, XP023117608, ISSN: 1050-1738, [retrieved on 19930901] * |
Also Published As
Publication number | Publication date |
---|---|
EP2231213B1 (en) | 2014-10-08 |
US8551072B2 (en) | 2013-10-08 |
EP2231213A2 (en) | 2010-09-29 |
JP2011505984A (en) | 2011-03-03 |
WO2009076413A2 (en) | 2009-06-18 |
US20090157042A1 (en) | 2009-06-18 |
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