WO2009131837A3 - Systems, methods and compositions for optical stimulation of target cells - Google Patents

Systems, methods and compositions for optical stimulation of target cells Download PDF

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Publication number
WO2009131837A3
WO2009131837A3 PCT/US2009/039949 US2009039949W WO2009131837A3 WO 2009131837 A3 WO2009131837 A3 WO 2009131837A3 US 2009039949 W US2009039949 W US 2009039949W WO 2009131837 A3 WO2009131837 A3 WO 2009131837A3
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WO
WIPO (PCT)
Prior art keywords
ion channel
light
systems
methods
compositions
Prior art date
Application number
PCT/US2009/039949
Other languages
French (fr)
Other versions
WO2009131837A2 (en
Inventor
Feng Zhang
Karl Deisseroth
Viviana Gradinaru
Original Assignee
The Board Of Trustees Of The Leland Stanford Junior University.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to MX2010011657A priority Critical patent/MX2010011657A/en
Priority to US12/988,567 priority patent/US8603790B2/en
Priority to CA2722278A priority patent/CA2722278C/en
Priority to EP16189132.0A priority patent/EP3165534B1/en
Priority to EP09735499.7A priority patent/EP2281039B1/en
Priority to AU2009238467A priority patent/AU2009238467B2/en
Priority to JP2011506348A priority patent/JP5801188B2/en
Priority to BRPI0911448-3A priority patent/BRPI0911448A2/en
Priority to ES09735499.7T priority patent/ES2608498T3/en
Application filed by The Board Of Trustees Of The Leland Stanford Junior University. filed Critical The Board Of Trustees Of The Leland Stanford Junior University.
Publication of WO2009131837A2 publication Critical patent/WO2009131837A2/en
Publication of WO2009131837A3 publication Critical patent/WO2009131837A3/en
Priority to IL208877A priority patent/IL208877A0/en
Priority to US13/718,243 priority patent/US8815582B2/en
Priority to US14/301,718 priority patent/US9249200B2/en
Priority to US14/694,845 priority patent/US9394347B2/en
Priority to AU2015207841A priority patent/AU2015207841B2/en
Priority to US15/194,381 priority patent/US9878176B2/en
Priority to US15/861,433 priority patent/US10350430B2/en
Priority to US16/415,567 priority patent/US20190336784A1/en

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Abstract

Methods, systems and devices are implemented in connection with light- responsive ion channel molecules. One such method is implemented using a light- activated ion channel molecule that responds to a light stimulus. The method includes engineering the light-activated ion channel molecule in a cell; and activating the ion channel molecule, in response to light stimulus that is provided to the ion channel molecule and that has properties that do not activate a ChR2 ion channel, to allow ions to pass through the light-activated ion channel molecule.
PCT/US2009/039949 2008-04-23 2009-04-08 Systems, methods and compositions for optical stimulation of target cells WO2009131837A2 (en)

Priority Applications (17)

Application Number Priority Date Filing Date Title
MX2010011657A MX2010011657A (en) 2008-04-23 2009-04-08 Systems, methods and compositions for optical stimulation of target cells.
US12/988,567 US8603790B2 (en) 2008-04-23 2009-04-08 Systems, methods and compositions for optical stimulation of target cells
CA2722278A CA2722278C (en) 2008-04-23 2009-04-08 Systems, methods and compositions for optical stimulation of target cells
EP16189132.0A EP3165534B1 (en) 2008-04-23 2009-04-08 Systems, methods and compositions for optical stimulation of target cells
EP09735499.7A EP2281039B1 (en) 2008-04-23 2009-04-08 Systems, methods and compositions for optical stimulation of target cells
AU2009238467A AU2009238467B2 (en) 2008-04-23 2009-04-08 Systems, methods and compositions for optical stimulation of target cells
JP2011506348A JP5801188B2 (en) 2008-04-23 2009-04-08 Systems, methods, and compositions for photostimulating target cells
BRPI0911448-3A BRPI0911448A2 (en) 2008-04-23 2009-04-08 systems, methods and compositions for optical simulation of target cells
ES09735499.7T ES2608498T3 (en) 2008-04-23 2009-04-08 Systems, methods and compositions for optical stimulation of target cells
IL208877A IL208877A0 (en) 2008-04-23 2010-10-21 Systems, methods and compostions for optical stimlation of target cells
US13/718,243 US8815582B2 (en) 2008-04-23 2012-12-18 Mammalian cell expressing Volvox carteri light-activated ion channel protein (VChR1)
US14/301,718 US9249200B2 (en) 2008-04-23 2014-06-11 Expression vector comprising a nucleotide sequence encoding a Volvox carteri light-activated ion channel protein (VChR1) and implantable device thereof
US14/694,845 US9394347B2 (en) 2008-04-23 2015-04-23 Methods for treating parkinson's disease by optically stimulating target cells
AU2015207841A AU2015207841B2 (en) 2008-04-23 2015-07-28 Systems, methods and compositions for optical stimulation of target cells
US15/194,381 US9878176B2 (en) 2008-04-23 2016-06-27 System utilizing Volvox carteri light-activated ion channel protein (VChR1) for optical stimulation of target cells
US15/861,433 US10350430B2 (en) 2008-04-23 2018-01-03 System comprising a nucleotide sequence encoding a volvox carteri light-activated ion channel protein (VCHR1)
US16/415,567 US20190336784A1 (en) 2008-04-23 2019-05-17 Systems, methods and compositions for optical stimulation of target cells

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4721908P 2008-04-23 2008-04-23
US61/047,219 2008-04-23

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US12/988,567 A-371-Of-International US8603790B2 (en) 2008-04-23 2009-04-08 Systems, methods and compositions for optical stimulation of target cells
US13/718,243 Division US8815582B2 (en) 2008-04-23 2012-12-18 Mammalian cell expressing Volvox carteri light-activated ion channel protein (VChR1)

Publications (2)

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WO2009131837A2 WO2009131837A2 (en) 2009-10-29
WO2009131837A3 true WO2009131837A3 (en) 2010-01-07

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PCT/US2009/039949 WO2009131837A2 (en) 2008-04-23 2009-04-08 Systems, methods and compositions for optical stimulation of target cells

Country Status (14)

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US (7) US8603790B2 (en)
EP (2) EP3165534B1 (en)
JP (2) JP5801188B2 (en)
KR (1) KR20110005280A (en)
AU (2) AU2009238467B2 (en)
BR (1) BRPI0911448A2 (en)
CA (1) CA2722278C (en)
ES (2) ES2608498T3 (en)
IL (1) IL208877A0 (en)
MX (1) MX2010011657A (en)
MY (1) MY169771A (en)
RU (1) RU2010147661A (en)
SG (1) SG189813A1 (en)
WO (1) WO2009131837A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108070615A (en) * 2017-12-25 2018-05-25 深圳先进技术研究院 A kind of carrier of regulation and control parathyroid gland PTH secretions and its application

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* Cited by examiner, † Cited by third party
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US9274099B2 (en) 2005-07-22 2016-03-01 The Board Of Trustees Of The Leland Stanford Junior University Screening test drugs to identify their effects on cell membrane voltage-gated ion channel
US9238150B2 (en) 2005-07-22 2016-01-19 The Board Of Trustees Of The Leland Stanford Junior University Optical tissue interface method and apparatus for stimulating cells
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BRPI0911448A2 (en) 2019-02-26
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