WO2009137800A3 - Electroporation device and method - Google Patents

Electroporation device and method Download PDF

Info

Publication number
WO2009137800A3
WO2009137800A3 PCT/US2009/043352 US2009043352W WO2009137800A3 WO 2009137800 A3 WO2009137800 A3 WO 2009137800A3 US 2009043352 W US2009043352 W US 2009043352W WO 2009137800 A3 WO2009137800 A3 WO 2009137800A3
Authority
WO
WIPO (PCT)
Prior art keywords
voltage
ablation
regions
electrically insulating
cells
Prior art date
Application number
PCT/US2009/043352
Other languages
French (fr)
Other versions
WO2009137800A2 (en
Inventor
William M. Appling
William C. Hamilton, Jr.
Paul W. Mikus
Original Assignee
Angiodynamics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Angiodynamics, Inc. filed Critical Angiodynamics, Inc.
Publication of WO2009137800A2 publication Critical patent/WO2009137800A2/en
Publication of WO2009137800A3 publication Critical patent/WO2009137800A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B18/1477—Needle-like probes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B18/1492—Probes or electrodes therefor having a flexible, catheter-like structure, e.g. for heart ablation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34—Trocars; Puncturing needles
    • A61B17/3417—Details of tips or shafts, e.g. grooves, expandable, bendable; Multiple coaxial sliding cannulas, e.g. for dilating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34—Trocars; Puncturing needles
    • A61B17/3417—Details of tips or shafts, e.g. grooves, expandable, bendable; Multiple coaxial sliding cannulas, e.g. for dilating
    • A61B2017/3454—Details of tips
    • A61B2017/3456—Details of tips blunt
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053—Mechanical features of the instrument of device
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00613—Irreversible electroporation

Abstract

Disclosed herein are methods and devices configured for pulsed voltage ablation that have two or more voltage delivery regions separated along a probe by electrically insulating regions. The electrically insulating regions are of sufficient lengths to allow the voltage delivery regions to be oppositely energized for delivering voltage pulses to treat cells within a predetermined ablation volume that can be delineated through representations indicating pulsed voltage ablation thresholds for cells.
PCT/US2009/043352 2008-05-09 2009-05-08 Electroporation device and method WO2009137800A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5183208P 2008-05-09 2008-05-09
US61/051,832 2008-05-09

Publications (2)

Publication Number Publication Date
WO2009137800A2 WO2009137800A2 (en) 2009-11-12
WO2009137800A3 true WO2009137800A3 (en) 2010-02-25

Family

ID=41265456

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2009/043352 WO2009137800A2 (en) 2008-05-09 2009-05-08 Electroporation device and method

Country Status (2)

Country Link
US (2) US20090281477A1 (en)
WO (1) WO2009137800A2 (en)

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