WO2010008238A3 - An immunochromatography detection sensor comprising optical waveguide and a detection method using the same - Google Patents

An immunochromatography detection sensor comprising optical waveguide and a detection method using the same Download PDF

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Publication number
WO2010008238A3
WO2010008238A3 PCT/KR2009/003960 KR2009003960W WO2010008238A3 WO 2010008238 A3 WO2010008238 A3 WO 2010008238A3 KR 2009003960 W KR2009003960 W KR 2009003960W WO 2010008238 A3 WO2010008238 A3 WO 2010008238A3
Authority
WO
WIPO (PCT)
Prior art keywords
same
optical waveguide
detection sensor
detection method
optical waveguides
Prior art date
Application number
PCT/KR2009/003960
Other languages
French (fr)
Other versions
WO2010008238A2 (en
Inventor
Yong Beom Shin
Min Gon Kim
Byeong Woo Bae
Original Assignee
Korea Research Institute Of Bioscience And Biotechnology
Infopia Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Korea Research Institute Of Bioscience And Biotechnology, Infopia Co., Ltd. filed Critical Korea Research Institute Of Bioscience And Biotechnology
Priority to US13/054,168 priority Critical patent/US20110189784A1/en
Publication of WO2010008238A2 publication Critical patent/WO2010008238A2/en
Publication of WO2010008238A3 publication Critical patent/WO2010008238A3/en
Priority to US14/222,291 priority patent/US9322824B2/en

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/90—Plate chromatography, e.g. thin layer or paper chromatography
    • G01N30/95—Detectors specially adapted therefor; Signal analysis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G01N33/54387—Immunochromatographic test strips
    • G01N33/54388—Immunochromatographic test strips based on lateral flow
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N2021/7756—Sensor type
    • G01N2021/7766—Capillary fill

Abstract

The present invention relates to an immunochromatographic detection sensor comprising optical waveguides and a detection method using the same, and more particularly, to an immunochromatographic detection sensor comprising optical waveguides, in which the optical waveguides are provided under the membrane, probe beams transmitted through the optical waveguide maximize the interaction frequency between evanescent wave generated on the surface of optical waveguide and the colored conjugate in the band formed on the membrane, and thus the absorbance signal from the colored conjugate is greatly amplified to improve the sample detection sensitivity, and a detection method using the same.
PCT/KR2009/003960 2008-07-18 2009-07-17 An immunochromatography detection sensor comprising optical waveguide and a detection method using the same WO2010008238A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US13/054,168 US20110189784A1 (en) 2008-07-18 2009-07-17 Immunochromatography Detection Sensor Comprising Optical Waveguide and a Detection Method Using the Same
US14/222,291 US9322824B2 (en) 2008-07-18 2014-03-21 Immunochromatography detection sensor comprising optical waveguide and a detection method using the same

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2008-0070196 2008-07-18
KR1020080070196A KR101025723B1 (en) 2008-07-18 2008-07-18 An immunochromatography detection sensor comprising optical waveguide and a detection method using the same

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US13/054,168 A-371-Of-International US20110189784A1 (en) 2008-07-18 2009-07-17 Immunochromatography Detection Sensor Comprising Optical Waveguide and a Detection Method Using the Same
US14/222,291 Continuation US9322824B2 (en) 2008-07-18 2014-03-21 Immunochromatography detection sensor comprising optical waveguide and a detection method using the same

Publications (2)

Publication Number Publication Date
WO2010008238A2 WO2010008238A2 (en) 2010-01-21
WO2010008238A3 true WO2010008238A3 (en) 2010-05-27

Family

ID=41550870

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2009/003960 WO2010008238A2 (en) 2008-07-18 2009-07-17 An immunochromatography detection sensor comprising optical waveguide and a detection method using the same

Country Status (3)

Country Link
US (2) US20110189784A1 (en)
KR (1) KR101025723B1 (en)
WO (1) WO2010008238A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101220284B1 (en) * 2010-12-27 2013-01-09 전자부품연구원 Optical module package for molecular diagnostic
JP5480222B2 (en) * 2011-10-05 2014-04-23 古河電気工業株式会社 Fluorescence immunochromatography method, kit and test strip used therefor
EP3153230A1 (en) * 2015-10-08 2017-04-12 The Provost, Fellows, Foundation Scholars, & the other members of Board, of the College of Holy and Undiv. Trinity of Queen Elizabeth near Dublin A method for the production of poly(methyl methacrylate) (pmma) membranes and uses thereof
US20170322359A1 (en) * 2016-05-04 2017-11-09 Samsung Display Co., Ltd. Display device
JP7032081B2 (en) * 2016-09-05 2022-03-08 株式会社ファンケル Test kit for ferritin detection and ferritin detection method
US10799861B2 (en) 2016-11-24 2020-10-13 Korea University Research And Business Foundation, Sejong Campus Biochemical-immunological hybrid biosensor and sensor system including the same
KR101960634B1 (en) 2018-04-19 2019-07-04 고려대학교 세종산학협력단 Single-channel, hybrid biosensor and sensor system including the same
KR102459863B1 (en) 2020-06-04 2022-10-26 홍익대학교세종캠퍼스산학협력단 Integrated-Optic Biosensor Structure Based on the Evanescent-Field and Two-Mode Power Coupling of Silicon Nitride Rib-Optical Waveguide

Citations (4)

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US7022515B2 (en) * 1993-05-18 2006-04-04 University Of Utah Research Foundation Waveguide immunosensor with coating chemistry and providing enhanced sensitivity
US7175811B2 (en) * 2000-04-28 2007-02-13 Edgelight Biosciences Micro-array evanescent wave fluorescence detection device
KR20070061837A (en) * 2004-09-28 2007-06-14 킴벌리-클라크 월드와이드, 인크. Detecting yeast infections using a lateral flow assay
KR20070090190A (en) * 2004-12-15 2007-09-05 킴벌리-클라크 월드와이드, 인크. Sample-efficient lateral flow immunoassay

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US5376556A (en) * 1989-10-27 1994-12-27 Abbott Laboratories Surface-enhanced Raman spectroscopy immunoassay
US5604105B1 (en) * 1990-10-12 1999-08-24 Spectral Diagnostics Inc Method and device for diagnosingand distinguishing chest pain in early onset thereof
JP4188538B2 (en) * 2000-04-12 2008-11-26 浜松ホトニクス株式会社 Immunochromatographic test piece measuring device
CA2506580C (en) * 2002-11-12 2010-08-17 Mochida Pharmaceutical Co., Ltd. Assay kit and antibody for human low molecular weight cd14
KR100704007B1 (en) 2006-01-17 2007-04-04 한국과학기술연구원 Lateral flow immunoassay kit based on chemiluminescence and chemifluorescence reaction and using method thereof
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Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7022515B2 (en) * 1993-05-18 2006-04-04 University Of Utah Research Foundation Waveguide immunosensor with coating chemistry and providing enhanced sensitivity
US7175811B2 (en) * 2000-04-28 2007-02-13 Edgelight Biosciences Micro-array evanescent wave fluorescence detection device
KR20070061837A (en) * 2004-09-28 2007-06-14 킴벌리-클라크 월드와이드, 인크. Detecting yeast infections using a lateral flow assay
KR20070090190A (en) * 2004-12-15 2007-09-05 킴벌리-클라크 월드와이드, 인크. Sample-efficient lateral flow immunoassay

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
"Immunosensors for Diagnostics", vol. 9, no. 1, 13 June 2001 (2001-06-13), pages 283 - 312, Retrieved from the Internet <URL:http://www3.interscience.wiley.com/journal/84002310/abstract> *

Also Published As

Publication number Publication date
US9322824B2 (en) 2016-04-26
US20110189784A1 (en) 2011-08-04
KR101025723B1 (en) 2011-04-04
US20140206103A1 (en) 2014-07-24
KR20100009347A (en) 2010-01-27
WO2010008238A2 (en) 2010-01-21

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