WO2010083300A3 - Interocular injector - Google Patents

Interocular injector Download PDF

Info

Publication number
WO2010083300A3
WO2010083300A3 PCT/US2010/021031 US2010021031W WO2010083300A3 WO 2010083300 A3 WO2010083300 A3 WO 2010083300A3 US 2010021031 W US2010021031 W US 2010021031W WO 2010083300 A3 WO2010083300 A3 WO 2010083300A3
Authority
WO
WIPO (PCT)
Prior art keywords
needle
lumen
disposed
eye
open
Prior art date
Application number
PCT/US2010/021031
Other languages
French (fr)
Other versions
WO2010083300A2 (en
Inventor
Zoran Novakovic
Rahul Bhagat
Shawn R. Davis
Original Assignee
Allergan, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan, Inc. filed Critical Allergan, Inc.
Priority to AU2010204695A priority Critical patent/AU2010204695A1/en
Priority to CA2749629A priority patent/CA2749629A1/en
Priority to EP10705457A priority patent/EP2391306A2/en
Publication of WO2010083300A2 publication Critical patent/WO2010083300A2/en
Publication of WO2010083300A3 publication Critical patent/WO2010083300A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007Methods or devices for eye surgery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/14Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16Intraocular lenses
    • A61F2/1662Instruments for inserting intraocular lenses into the eye
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/14Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16Intraocular lenses
    • A61F2/1662Instruments for inserting intraocular lenses into the eye
    • A61F2/167Instruments for inserting intraocular lenses into the eye with pushable plungers

Abstract

An intraocular injector includes a syringe body having open-ended cone disposed in one end thereof along with a piston disposed in the body. A transparent implant holder (32) having a lumen therein is aligned with an open-ended cone, a needle include a proximal end and a distal end with a bevel (50) disposed on the distal end of the needle. A plunger (28) affixed to the piston and slidable within a holder lumen and needle lumen is provided for injecting solid intraocular implants into an eye. A cylindrical syringe body shape facilitates control over the needle bevel orientation during injection of the implant into the eye.
PCT/US2010/021031 2009-01-16 2010-01-14 Interocular injector WO2010083300A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU2010204695A AU2010204695A1 (en) 2009-01-16 2010-01-14 Interocular injector
CA2749629A CA2749629A1 (en) 2009-01-16 2010-01-14 Interocular injector
EP10705457A EP2391306A2 (en) 2009-01-16 2010-01-14 Interocular injector

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12/355,709 US8545554B2 (en) 2009-01-16 2009-01-16 Intraocular injector
US12/355,709 2009-01-16

Publications (2)

Publication Number Publication Date
WO2010083300A2 WO2010083300A2 (en) 2010-07-22
WO2010083300A3 true WO2010083300A3 (en) 2010-09-16

Family

ID=42261945

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2010/021031 WO2010083300A2 (en) 2009-01-16 2010-01-14 Interocular injector

Country Status (5)

Country Link
US (2) US8545554B2 (en)
EP (1) EP2391306A2 (en)
AU (1) AU2010204695A1 (en)
CA (1) CA2749629A1 (en)
WO (1) WO2010083300A2 (en)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6638239B1 (en) 2000-04-14 2003-10-28 Glaukos Corporation Apparatus and method for treating glaucoma
US7867186B2 (en) 2002-04-08 2011-01-11 Glaukos Corporation Devices and methods for treatment of ocular disorders
EP1977724A1 (en) 2001-04-07 2008-10-08 Glaukos Corporation System for treating ocular disorders
US7331984B2 (en) 2001-08-28 2008-02-19 Glaukos Corporation Glaucoma stent for treating glaucoma and methods of use
US20070202186A1 (en) 2006-02-22 2007-08-30 Iscience Interventional Corporation Apparatus and formulations for suprachoroidal drug delivery
US8197435B2 (en) 2006-05-02 2012-06-12 Emory University Methods and devices for drug delivery to ocular tissue using microneedle
CA2668954C (en) 2006-11-10 2020-09-08 Glaukos Corporation Uveoscleral shunt and methods for implanting same
US8623395B2 (en) 2010-01-29 2014-01-07 Forsight Vision4, Inc. Implantable therapeutic device
CA2757037C (en) 2009-01-29 2019-08-06 Forsight Vision4, Inc. Posterior segment drug delivery
AU2011207281B2 (en) 2010-01-22 2016-10-20 Allergan, Inc. Intracameral sustained release therapeutic agent implants
US10166142B2 (en) 2010-01-29 2019-01-01 Forsight Vision4, Inc. Small molecule delivery with implantable therapeutic device
RS62540B1 (en) 2010-08-05 2021-12-31 Forsight Vision4 Inc Apparatus to treat an eye
AU2011285548B2 (en) 2010-08-05 2014-02-06 Forsight Vision4, Inc. Combined drug delivery methods and apparatus
RS61601B1 (en) 2010-08-05 2021-04-29 Forsight Vision4 Inc Injector apparatus for drug delivery
US20120271272A1 (en) 2010-10-15 2012-10-25 Iscience Interventional Corporation Device for ocular access
AU2011329656B2 (en) 2010-11-19 2017-01-05 Forsight Vision4, Inc. Therapeutic agent formulations for implanted devices
EP2726016B1 (en) 2011-06-28 2023-07-19 ForSight Vision4, Inc. An apparatus for collecting a sample of fluid from a reservoir chamber of a therapeutic device for the eye
EP2567674B1 (en) * 2011-09-07 2015-05-06 SDI Surgical Device International GmbH Modular intraocular lens injector
WO2013040247A2 (en) 2011-09-16 2013-03-21 Forsight Vision4, Inc. Fluid exchange apparatus and methods
CN202322807U (en) * 2011-11-18 2012-07-11 彭建军 Microscopic injection needle mounting module and needle holder assembly
WO2013116061A1 (en) 2012-02-03 2013-08-08 Forsight Vision4, Inc. Insertion and removal methods and apparatus for therapeutic devices
WO2013148275A2 (en) 2012-03-26 2013-10-03 Glaukos Corporation System and method for delivering multiple ocular implants
AU2013204739B2 (en) * 2012-04-21 2016-10-20 Paul Jason Barrot Apparatus for plugging holes
CN104884049A (en) 2012-11-08 2015-09-02 克莱尔塞德生物医学股份有限公司 Methods and devices for the treatment of ocular diseases in human subjects
CA2905496A1 (en) 2013-03-14 2014-09-25 Forsight Vision4, Inc. Systems for sustained intraocular delivery of low solubility compounds from a port delivery system implant
US9592151B2 (en) 2013-03-15 2017-03-14 Glaukos Corporation Systems and methods for delivering an ocular implant to the suprachoroidal space within an eye
AU2014241163B2 (en) 2013-03-28 2018-09-27 Forsight Vision4, Inc. Ophthalmic implant for delivering therapeutic substances
CA153455S (en) * 2013-04-22 2015-01-06 Santen Pharmaceutical Co Ltd Operation-guiding cylinder for intraocular lens implantation device
AU2014259694B2 (en) 2013-05-03 2018-11-08 Clearside Biomedical, Inc. Apparatus and methods for ocular injection
US10188550B2 (en) 2013-06-03 2019-01-29 Clearside Biomedical, Inc. Apparatus and methods for drug delivery using multiple reservoirs
US9445941B2 (en) * 2013-11-07 2016-09-20 Drug Delivery Company, Llc Bioresorbable drug eluting intravitreal implant system and method
RU2728195C2 (en) 2014-02-26 2020-07-28 Аллерган, Инк. Device for delivery of intraocular implant and methods of its use
RU2710491C2 (en) 2014-06-20 2019-12-26 Клиасайд Байомедикал, Инк. Device for drug injection into ocular tissue and method for drug injection into ocular tissue
WO2016011191A1 (en) 2014-07-15 2016-01-21 Forsight Vision4, Inc. Ocular implant delivery device and method
SG11201700943TA (en) 2014-08-08 2017-03-30 Forsight Vision4 Inc Stable and soluble formulations of receptor tyrosine kinase inhibitors, and methods of preparation thereof
USD750223S1 (en) 2014-10-14 2016-02-23 Clearside Biomedical, Inc. Medical injector for ocular injection
CA2967330A1 (en) 2014-11-10 2016-05-19 Forsight Vision4, Inc. Expandable drug delivery devices and methods of use
AU2016354549B2 (en) * 2015-11-13 2020-11-26 Johnson & Johnson Surgical Vision, Inc. Intraocular lens insertion device
CN113069681B (en) 2015-11-20 2022-12-23 弗赛特影像4股份有限公司 Method of manufacturing a therapeutic device for sustained drug delivery
US10390901B2 (en) 2016-02-10 2019-08-27 Clearside Biomedical, Inc. Ocular injection kit, packaging, and methods of use
ES2837524T3 (en) 2016-04-05 2021-06-30 Forsight Vision4 Inc Implantable ocular drug delivery devices
AU2017246114B2 (en) * 2016-04-08 2022-03-17 Allergan, Inc. Aspiration and injection device
JP2019514581A (en) 2016-05-02 2019-06-06 クリアサイド バイオメディカル,インコーポレイテッド Systems and methods for ocular drug delivery
IL305537A (en) 2016-08-12 2023-10-01 Clearside Biomedical Inc Devices and methods for adjusting the insertion depth of a needle for medicament delivery
CN108852614B (en) * 2017-05-10 2023-09-15 上海中医药大学附属龙华医院 Lacrimal apparatus Guan Shuansai injector
US11376040B2 (en) 2017-10-06 2022-07-05 Glaukos Corporation Systems and methods for delivering multiple ocular implants
USD846738S1 (en) 2017-10-27 2019-04-23 Glaukos Corporation Implant delivery apparatus
CN111655206B (en) 2017-11-21 2022-10-14 弗赛特影像4股份有限公司 Fluid exchange device for expandable port delivery system and method of use
WO2019217678A1 (en) * 2018-05-09 2019-11-14 North Carolina State University Applicator for corneal therapeutics
US11464914B2 (en) * 2019-10-21 2022-10-11 Ripple Therapeutics Corporation Intravitreal injector
WO2023232963A1 (en) 2022-06-03 2023-12-07 Boehringer Ingelheim International Gmbh Implanting device for inserting an implant into tissue

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0270257A1 (en) * 1986-11-07 1988-06-08 THE COOPER COMPANIES, INC. (formerly called CooperVision, Inc.) Tool for inserting compressible intraocular lenses into the eye and method
US20020082609A1 (en) * 2000-12-21 2002-06-27 Green George F. Intraocular lens and additive packaging system
US20080097459A1 (en) * 2004-04-22 2008-04-24 Advanced Vision Science, Inc. Device For The Insertion Of Deformable Intra-Ocular Lenses

Family Cites Families (110)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2513014A (en) * 1946-11-18 1950-06-27 Abbott Lab Apparatus for implanting medicinal pellets subcutaneously
US2717599A (en) * 1952-02-18 1955-09-13 Huber Jennie Needle structure
US3220413A (en) 1961-04-03 1965-11-30 Sunnen Joseph Applicator
US3238941A (en) * 1963-06-19 1966-03-08 Frost Eng Dev Balling gun
US3698390A (en) * 1969-10-27 1972-10-17 Frank Donald Ferris Dispensing for medicaments
US3941128A (en) * 1970-11-10 1976-03-02 Affiliated Hospital Products, Inc. Fluid dispensing arrangement
US3937370A (en) * 1974-08-14 1976-02-10 Baxter Laboratories, Inc. Controlled depth aspiration cannula
US4144317A (en) * 1975-05-30 1979-03-13 Alza Corporation Device consisting of copolymer having acetoxy groups for delivering drugs
US4105030A (en) * 1977-01-03 1978-08-08 Syntex (U.S.A.) Inc. Implant apparatus
US4304765A (en) 1980-10-14 1981-12-08 Alza Corporation Ocular insert housing steroid in two different therapeutic forms
US4383992A (en) * 1982-02-08 1983-05-17 Lipari John M Water-soluble steroid compounds
IT1229075B (en) 1985-04-05 1991-07-17 Fidia Farmaceutici Topical compsn. contg. hyaluronic acid deriv. as vehicle
US4521210A (en) * 1982-12-27 1985-06-04 Wong Vernon G Eye implant for relieving glaucoma, and device and method for use therewith
GB2138298B (en) * 1983-04-21 1986-11-05 Hundon Forge Ltd Pellet implanter
US4727064A (en) * 1984-04-25 1988-02-23 The United States Of America As Represented By The Department Of Health And Human Services Pharmaceutical preparations containing cyclodextrin derivatives
US6407079B1 (en) * 1985-07-03 2002-06-18 Janssen Pharmaceutica N.V. Pharmaceutical compositions containing drugs which are instable or sparingly soluble in water and methods for their preparation
US4668506A (en) * 1985-08-16 1987-05-26 Bausch & Lomb Incorporated Sustained-release formulation containing and amino acid polymer
SU1419676A1 (en) * 1985-12-16 1988-08-30 Московский научно-исследовательский институт микрохирургии глаза Apparatus for coagulation of biological tissues
US4959217A (en) * 1986-05-22 1990-09-25 Syntex (U.S.A.) Inc. Delayed/sustained release of macromolecules
US4803075A (en) * 1986-06-25 1989-02-07 Collagen Corporation Injectable implant composition having improved intrudability
ES2053019T3 (en) * 1986-07-30 1994-07-16 Sumitomo Pharma SOLID PREPARATION ADMINISTRATION INSTRUMENT.
CA1325486C (en) 1986-10-31 1993-12-21 Takayuki Okada Thermoplastic resin composition
US4852566A (en) * 1986-11-07 1989-08-01 Callahan Wayne B Device for implantation of intraocular lens
US4850970A (en) * 1987-03-26 1989-07-25 American Home Products, Corp. Two part mastitis cannula cap
DE3802158A1 (en) 1987-08-11 1989-02-23 Hoechst Ag DEVICE FOR APPLICATION OF IMPLANTS
ATE71543T1 (en) * 1987-08-18 1992-02-15 Akzo Nv INJECTION DEVICE FOR AN IMPLANT.
US4834094A (en) * 1987-10-07 1989-05-30 Patton Medical Technologies, Inc. "Canoe" apparatus for inserting intra-ocular lens into the eye
US4997652A (en) * 1987-12-22 1991-03-05 Visionex Biodegradable ocular implants
US4853224A (en) * 1987-12-22 1989-08-01 Visionex Biodegradable ocular implants
US4846809A (en) * 1988-02-29 1989-07-11 Winifred Sims Needle tip protective device
US4920104A (en) * 1988-05-16 1990-04-24 Medchem Products, Inc. Sodium hyaluronate composition
US4907587A (en) * 1988-10-12 1990-03-13 Fedorov Svjatoslav N Method for surgical correction of mixed and hypermetropic astigmatism and a device for carrying same into effect
DE3903956A1 (en) * 1989-02-10 1990-08-16 Guenter Dr Lohrmann GUIDE DEVICE FOR A PUNCHING BIOPSIA NEEDLE CONNECTED TO A BIOPSI PUNCHING DEVICE
US5098443A (en) 1989-03-23 1992-03-24 University Of Miami Method of implanting intraocular and intraorbital implantable devices for the controlled release of pharmacological agents
US6271216B1 (en) * 1989-07-24 2001-08-07 Allergan Stable solution of hyaluronate in a balanced salt medium
US5817075A (en) * 1989-08-14 1998-10-06 Photogenesis, Inc. Method for preparation and transplantation of planar implants and surgical instrument therefor
US5336206A (en) * 1989-08-15 1994-08-09 United States Surgical Corporation Trocar penetration depth indicator and guide tube positioning device
US5284479A (en) * 1989-08-30 1994-02-08 N.V. Nederlandsche Apparatenfabriek Nedap Implanter
NL8902186A (en) 1989-08-30 1991-03-18 Nedap Nv RECHARGEABLE IMPLANT TOOL WITH AUTOMATIC RELEASE.
JPH03158171A (en) * 1989-11-17 1991-07-08 Masataka Saito Cap integral type disposal injection needle
US5164188A (en) 1989-11-22 1992-11-17 Visionex, Inc. Biodegradable ocular implants
GB2240718A (en) * 1990-02-09 1991-08-14 Hundon Forge Ltd Implanting device with needle cover
US5256408A (en) * 1990-06-12 1993-10-26 Insite Vision Incorporated Aminosteroids for ophthalmic use
US5124154A (en) * 1990-06-12 1992-06-23 Insite Vision Incorporated Aminosteroids for ophthalmic use
DE4030492C1 (en) * 1990-09-26 1991-09-05 Adatomed Pharmazeutische Und Medizintechnische Gesellschaft Mbh, 8000 Muenchen, De
KR0185215B1 (en) * 1990-11-30 1999-05-01 요시다 쇼오지 A controlled-release pharmaceutical preparation for intra-ocular implant
US5492936A (en) * 1990-11-30 1996-02-20 Allergan, Inc. Bimodal molecular weight hyaluronate formulations and methods for using same
US5378475A (en) * 1991-02-21 1995-01-03 University Of Kentucky Research Foundation Sustained release drug delivery devices
US5188607A (en) * 1991-11-12 1993-02-23 Thomas Wu Valve catheter connector assembly
US5178635A (en) 1992-05-04 1993-01-12 Allergan, Inc. Method for determining amount of medication in an implantable device
US5250026A (en) * 1992-05-27 1993-10-05 Destron/Idi, Inc. Adjustable precision transponder injector
US5324718A (en) * 1992-07-14 1994-06-28 Thorsteinn Loftsson Cyclodextrin/drug complexation
US5807400A (en) * 1992-09-30 1998-09-15 Staar Surgical Company, Inc. Deformable intraocular lens insertion system
US5620450A (en) * 1992-09-30 1997-04-15 Staar Surgical Company, Inc. Transverse hinged deformable intraocular lens injecting apparatus
US5494901A (en) * 1993-01-05 1996-02-27 Javitt; Jonathan C. Topical compositions for the eye comprising a β-cyclodextrin derivative and a therapeutic agent
US5770589A (en) * 1993-07-27 1998-06-23 The University Of Sydney Treatment of macular degeneration
US5443505A (en) * 1993-11-15 1995-08-22 Oculex Pharmaceuticals, Inc. Biocompatible ocular implants
US5516522A (en) * 1994-03-14 1996-05-14 Board Of Supervisors Of Louisiana State University Biodegradable porous device for long-term drug delivery with constant rate release and method of making the same
US5466233A (en) 1994-04-25 1995-11-14 Escalon Ophthalmics, Inc. Tack for intraocular drug delivery and method for inserting and removing same
US5451213A (en) * 1994-05-31 1995-09-19 Log Plastic Products Protective device for syringe needles
US5746718A (en) * 1994-07-05 1998-05-05 Steyn; Ricardo Sheath Oxford Needle protective device
US5837276A (en) 1994-09-02 1998-11-17 Delab Apparatus for the delivery of elongate solid drug compositions
US5582591A (en) 1994-09-02 1996-12-10 Delab Delivery of solid drug compositions
US5542920A (en) * 1994-09-12 1996-08-06 Delab Needle-less parenteral introduction device
US5576311A (en) 1994-11-30 1996-11-19 Pharmos Corporation Cyclodextrins as suspending agents for pharmaceutical suspensions
US5869079A (en) * 1995-06-02 1999-02-09 Oculex Pharmaceuticals, Inc. Formulation for controlled release of drugs by combining hydrophilic and hydrophobic agents
US5656026A (en) * 1995-10-27 1997-08-12 Joseph; Neil H. Method of in vitro testing one-way pressure gradient limiting valved glaucoma drainage implants
US5725521A (en) * 1996-03-29 1998-03-10 Eclipse Surgical Technologies, Inc. Depth stop apparatus and method for laser-assisted transmyocardial revascularization and other surgical applications
US5824001A (en) 1996-06-10 1998-10-20 Becton Dickinson And Company Radially vented flashback chamber and plug assembly
US5651774A (en) * 1996-09-11 1997-07-29 William J. Taranto Hypodermic syringe with safety shield and method of using same
US5941250A (en) * 1996-11-21 1999-08-24 University Of Louisville Research Foundation Inc. Retinal tissue implantation method
US5876373A (en) * 1997-04-04 1999-03-02 Eclipse Surgical Technologies, Inc. Steerable catheter
JP2001513369A (en) * 1997-08-11 2001-09-04 アラーガン・セイルズ・インコーポレイテッド Sterile bioerodible implant devices and methods with improved biocompatibility
US6605093B1 (en) * 1997-10-24 2003-08-12 Tekia, Inc. Device and method for use with an ophthalmologic insertor apparatus
US6251418B1 (en) * 1997-12-18 2001-06-26 C.R. Bard, Inc. Systems and methods for local delivery of an agent
CA2316949A1 (en) * 1997-12-29 1999-07-08 Alza Corporation Implanter device for subcutaneous implants
US5957892A (en) * 1998-03-12 1999-09-28 Specialized Health Products, Inc. Safety catheter insertion apparatus and methods
US20040152664A1 (en) * 1998-09-02 2004-08-05 Allergan, Inc. Prednisolone compositions
US20020198174A1 (en) 2001-05-07 2002-12-26 Allergan Sales, Inc. Disinfecting and solubilizing steroid compositions
EP1109581A1 (en) * 1998-09-02 2001-06-27 Allergan Sales, Inc. Preserved cyclodextrin-containing compositions
US7651505B2 (en) * 2002-06-17 2010-01-26 Senorx, Inc. Plugged tip delivery for marker placement
US6217895B1 (en) * 1999-03-22 2001-04-17 Control Delivery Systems Method for treating and/or preventing retinal diseases with sustained release corticosteroids
US6159218A (en) 1999-05-19 2000-12-12 Aramant; Robert B. Retinal tissue implantation tool
US6331313B1 (en) 1999-10-22 2001-12-18 Oculex Pharmaceticals, Inc. Controlled-release biocompatible ocular drug delivery implant devices and methods
US6450937B1 (en) * 1999-12-17 2002-09-17 C. R. Bard, Inc. Needle for implanting brachytherapy seeds
AUPQ496500A0 (en) * 2000-01-06 2000-02-03 University Of Sydney, The Kit
US6395294B1 (en) * 2000-01-13 2002-05-28 Gholam A. Peyman Method of visualization of the vitreous during vitrectomy
US20040170665A1 (en) * 2000-06-02 2004-09-02 Allergan, Inc. Intravitreal botulinum toxin implant
US6726918B1 (en) * 2000-07-05 2004-04-27 Oculex Pharmaceuticals, Inc. Methods for treating inflammation-mediated conditions of the eye
US6648857B1 (en) 2000-07-21 2003-11-18 Barbara K. Pedigo Disposable needle stick prevention aid to prevent needle stick injury
DE60135352D1 (en) * 2000-08-30 2008-09-25 Univ Johns Hopkins DEVICE FOR INTRA-OCCULAR ACTIVE AGGREGATION
US6554760B2 (en) * 2000-10-25 2003-04-29 Gary A. Lamoureux Pre-loaded needle assembly
ATE424808T1 (en) * 2000-11-15 2009-03-15 Chandavarkar Mohan A PHARMACEUTICAL COMPOSITIONS CONTAINING CORTICOSTEROIDS AND ANTI-INFECTIVES
CA2429998C (en) * 2000-11-29 2012-01-17 Oculex Pharmaceuticals, Inc. Intraocular implants for preventing transplant rejection in the eye
US6713081B2 (en) * 2001-03-15 2004-03-30 The United States Of America As Represented By The Department Of Health And Human Services Ocular therapeutic agent delivery devices and methods for making and using such devices
GEP20063755B (en) * 2001-11-09 2006-02-27 Eyetech Pharmaceuticals Use of VEGF Inhibiting Agents for Treating Ocular Neovascular Diseases
EP1323450B1 (en) 2001-12-18 2004-09-22 Rexam Pharma GmbH Syringe device
JP2005517468A (en) * 2002-02-14 2005-06-16 フォトジェネシス インコーポレイテッド Subretinal transplant device and cannula used with the same
US6639116B2 (en) 2002-03-15 2003-10-28 Millken & Company Simplified methods of making 1,3-cyclohexadiene
US20030208218A1 (en) 2002-05-02 2003-11-06 Kenneth E. Kadziauskas Ultrasonic needle cover
US6921385B2 (en) * 2002-08-05 2005-07-26 Alcon, Inc. Apparatus for delivery of fluid to opthalmic surgical handpiece
US7468065B2 (en) * 2002-09-18 2008-12-23 Allergan, Inc. Apparatus for delivery of ocular implants
US6899717B2 (en) * 2002-09-18 2005-05-31 Allergan, Inc. Methods and apparatus for delivery of ocular implants
GB2395196B (en) * 2002-11-14 2006-12-27 Univ Cardiff Microfluidic device and methods for construction and application
ATE333251T1 (en) 2002-11-18 2006-08-15 Meyer & Co Ag Anton LENS INTRODUCTION DEVICE WITH FINGER RING
US20050032747A1 (en) * 2003-07-01 2005-02-10 Wilmin Bartolini COX-2 and FAAH inhibitors
US7429263B2 (en) * 2003-08-28 2008-09-30 Bausch & Lomb Incorporated Preloaded IOL injector
US7589057B2 (en) * 2004-04-30 2009-09-15 Allergan, Inc. Oil-in-water method for making alpha-2 agonist polymeric drug delivery systems
JP2008517733A (en) * 2004-10-25 2008-05-29 アルファスパイン インコーポレイテッド Pedicle screw system and assembly / installation method of the system
US20080200921A1 (en) * 2007-02-15 2008-08-21 Downer David A Lens Delivery System

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0270257A1 (en) * 1986-11-07 1988-06-08 THE COOPER COMPANIES, INC. (formerly called CooperVision, Inc.) Tool for inserting compressible intraocular lenses into the eye and method
US20020082609A1 (en) * 2000-12-21 2002-06-27 Green George F. Intraocular lens and additive packaging system
US20080097459A1 (en) * 2004-04-22 2008-04-24 Advanced Vision Science, Inc. Device For The Insertion Of Deformable Intra-Ocular Lenses

Also Published As

Publication number Publication date
CA2749629A1 (en) 2010-07-22
US8545554B2 (en) 2013-10-01
WO2010083300A2 (en) 2010-07-22
AU2010204695A1 (en) 2011-08-11
US20140031833A1 (en) 2014-01-30
US20100185205A1 (en) 2010-07-22
EP2391306A2 (en) 2011-12-07

Similar Documents

Publication Publication Date Title
WO2010083300A3 (en) Interocular injector
WO2009089409A3 (en) Intravitreal injection system having coaxial cannulae and use thereof
WO2012045667A3 (en) A sprinkler cannula
CA2592503A1 (en) Preloaded iol injector and method
WO2009132212A3 (en) Device to store and inject corneal graft
WO2008060869A3 (en) Intraocular lens injection apparatus and method
IN2012DN01590A (en)
NZ583832A (en) Implant insertion tool with a tissue stop configuired to engage tissue
WO2008076584A3 (en) Injector apparatus for use with intraocular lenses and methods of use
SI2384210T1 (en) Injection device
WO2006113474A3 (en) Corneal implant injector assembly and methods of use
ATE514395T1 (en) METHOD OF PREPARING A PRELOADED INTRAOCULAR LENS INJECTOR
WO2013027973A3 (en) Surgical instrument for skin tissue lift surgery
WO2013126853A3 (en) Devices for targeted delivery of therapeutic implants
MX2011008381A (en) Automated intraocular lens injector device.
WO2012168691A8 (en) Injection apparatus with needle housing for desensitising skin
NZ701069A (en) Methods and devices for drug delivery to ocular tissue using microneedle
EP1438978A3 (en) Liquid injection needle and liquid injection device
UA103228C2 (en) Apparatus for injecting a pharmaceutical with automatic syringe retraction following injection
WO2010123305A3 (en) Syringe for injecting surgical thread
WO2005112789A3 (en) Suture device
WO2006071597A3 (en) Preloaded iol injector and method
WO2008096821A1 (en) Injector for eye
WO2008116031A3 (en) Safety medical syringe with retractable needle and including a plunger that is received within a barrel
MX2012002516A (en) Injection needle assembly and drug injection device.

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 10705457

Country of ref document: EP

Kind code of ref document: A2

WWE Wipo information: entry into national phase

Ref document number: 2749629

Country of ref document: CA

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 2010204695

Country of ref document: AU

REEP Request for entry into the european phase

Ref document number: 2010705457

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2010705457

Country of ref document: EP

ENP Entry into the national phase

Ref document number: 2010204695

Country of ref document: AU

Date of ref document: 20100114

Kind code of ref document: A