WO2010143200A3 - A coronary stent with nano coating of drug free polymer and a process for preparation thereof - Google Patents

A coronary stent with nano coating of drug free polymer and a process for preparation thereof Download PDF

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Publication number
WO2010143200A3
WO2010143200A3 PCT/IN2010/000370 IN2010000370W WO2010143200A3 WO 2010143200 A3 WO2010143200 A3 WO 2010143200A3 IN 2010000370 W IN2010000370 W IN 2010000370W WO 2010143200 A3 WO2010143200 A3 WO 2010143200A3
Authority
WO
WIPO (PCT)
Prior art keywords
preparation
nano
nano coating
coronary stent
coronary
Prior art date
Application number
PCT/IN2010/000370
Other languages
French (fr)
Other versions
WO2010143200A2 (en
Inventor
S. Sundar Manoharan
T. R. Muralidharan
Original Assignee
Indian Institute Of Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indian Institute Of Technology filed Critical Indian Institute Of Technology
Publication of WO2010143200A2 publication Critical patent/WO2010143200A2/en
Publication of WO2010143200A3 publication Critical patent/WO2010143200A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/12—Nanosized materials, e.g. nanofibres, nanoparticles, nanowires, nanotubes; Nanostructured surfaces
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2420/00—Materials or methods for coatings medical devices
    • A61L2420/04—Coatings containing a composite material such as inorganic/organic, i.e. material comprising different phases

Abstract

The present invention relates to a medical device carrying a nano coating by utilizing the same on the coronary stent systems and a process for preparation thereof. The inventive coronary stents can be provided with various advantages/properties and properties thereof. The material coated is a biocompatible bio-formulation which by means of a physical vapor deposition route ensures a very thin coating (5 to 40 nm). In-vitro studies on human blood suggest that, the nano coated stent is devoid of platelet adhesion. Such a hydrophobic nano coated stent surface reduces the chances of thrombosis as a result it provides a viable alternative to drug eluting stents.
PCT/IN2010/000370 2009-06-11 2010-06-04 A coronary stent with nano coating of drug free polymer and a process for preparation thereof WO2010143200A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1197/DEL/2009 2009-06-11
IN1197DE2009 2009-06-11

Publications (2)

Publication Number Publication Date
WO2010143200A2 WO2010143200A2 (en) 2010-12-16
WO2010143200A3 true WO2010143200A3 (en) 2011-03-17

Family

ID=42754874

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2010/000370 WO2010143200A2 (en) 2009-06-11 2010-06-04 A coronary stent with nano coating of drug free polymer and a process for preparation thereof

Country Status (1)

Country Link
WO (1) WO2010143200A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007142579A1 (en) * 2006-06-05 2007-12-13 Bactiguard Ab A polymer matrix, uses thereof and a method of manufacturing the same
US20090118813A1 (en) * 2007-11-02 2009-05-07 Torsten Scheuermann Nano-patterned implant surfaces

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5466509A (en) 1993-01-15 1995-11-14 Impra, Inc. Textured, porous, expanded PTFE
EP0621015B1 (en) 1993-04-23 1998-03-18 Schneider (Europe) Ag Stent with a covering layer of elastic material and method for applying the layer on the stent
JPH09501585A (en) 1993-08-18 1997-02-18 ダブリュ．エル．ゴア アンド アソシエイツ，インコーポレイティド Thin and seamless porous polytetrafluoroethylene tube
US5888591A (en) 1996-05-06 1999-03-30 Massachusetts Institute Of Technology Chemical vapor deposition of fluorocarbon polymer thin films
US6364903B2 (en) 1999-03-19 2002-04-02 Meadox Medicals, Inc. Polymer coated stent
US8435287B2 (en) 2004-03-30 2013-05-07 Toyo Advanced Technologies Co., Ltd. Stent and method for fabricating the same
EP1804958A4 (en) 2004-09-17 2010-11-17 Nanosys Inc Nanostructured thin films and their uses
US20060129215A1 (en) 2004-12-09 2006-06-15 Helmus Michael N Medical devices having nanostructured regions for controlled tissue biocompatibility and drug delivery
US8263104B2 (en) 2007-06-08 2012-09-11 Northwestern University Polymer nanofilm coatings
WO2009039429A2 (en) 2007-09-21 2009-03-26 Boston Scientific Scimed, Inc. Therapeutic agent-eluting medical devices having textured polymeric surfaces
US20090104434A1 (en) 2007-10-17 2009-04-23 Jennifer Hoyt Lalli Conformal multifunctional coatings

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007142579A1 (en) * 2006-06-05 2007-12-13 Bactiguard Ab A polymer matrix, uses thereof and a method of manufacturing the same
US20090118813A1 (en) * 2007-11-02 2009-05-07 Torsten Scheuermann Nano-patterned implant surfaces

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
K. P. GRYTSENKO, S. SCHRADER: "Nanoclusters in polymer matrices prepared by co-deposition from a gas phase", ADVANCES IN COLLID AND INTERFACE SCIENCE, vol. 116, 19 October 2005 (2005-10-19), pages 263 - 276, XP002615548 *
LIU ZHIJIAN, LE XIAOYUN, JIANG XINGLIU, HAN LIJUN: "Preparation of nanometer thin films with intense pulsed electron beam ablation", SURFACE AND COATINGS TECHNOLOGY, 2005, pages 325 - 328, XP002615544 *

Also Published As

Publication number Publication date
WO2010143200A2 (en) 2010-12-16

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