WO2011031301A3 - Intrapericardial delivery of periostin - Google Patents

Intrapericardial delivery of periostin Download PDF

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Publication number
WO2011031301A3
WO2011031301A3 PCT/US2010/002365 US2010002365W WO2011031301A3 WO 2011031301 A3 WO2011031301 A3 WO 2011031301A3 US 2010002365 W US2010002365 W US 2010002365W WO 2011031301 A3 WO2011031301 A3 WO 2011031301A3
Authority
WO
WIPO (PCT)
Prior art keywords
periostin
delivery
fragments
variants
compositions
Prior art date
Application number
PCT/US2010/002365
Other languages
French (fr)
Other versions
WO2011031301A2 (en
Inventor
Dennis Ladage
Yoshiaki Kawase
Bernhard Kuhn
Roger Joseph Hajjar
Original Assignee
Mount Sinai School Of Medicine Of New York University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mount Sinai School Of Medicine Of New York University filed Critical Mount Sinai School Of Medicine Of New York University
Publication of WO2011031301A2 publication Critical patent/WO2011031301A2/en
Publication of WO2011031301A3 publication Critical patent/WO2011031301A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body

Abstract

Compositions and methods for delivery of periostin or fragments or variants thereof to or near the pericardial space are provided. In some embodiments, a sustained release vehicle is used to deliver periostin or fragments or variants thereof in a controlled manner to treat the heart of a subject. The sustained release vehicle may be, for example, a hydrogel particle. In certain embodiments, compositions and methods are provided for inhibiting formation of tissue adhesions within the pericardial space.
PCT/US2010/002365 2009-08-28 2010-08-27 Intrapericardial delivery of periostin WO2011031301A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23797109P 2009-08-28 2009-08-28
US61/237,971 2009-08-28

Publications (2)

Publication Number Publication Date
WO2011031301A2 WO2011031301A2 (en) 2011-03-17
WO2011031301A3 true WO2011031301A3 (en) 2011-09-29

Family

ID=43732729

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/US2010/002362 WO2011031299A1 (en) 2009-08-28 2010-08-27 Intrapericardial injections
PCT/US2010/002365 WO2011031301A2 (en) 2009-08-28 2010-08-27 Intrapericardial delivery of periostin

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PCT/US2010/002362 WO2011031299A1 (en) 2009-08-28 2010-08-27 Intrapericardial injections

Country Status (1)

Country Link
WO (2) WO2011031299A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8257434B2 (en) 2007-12-18 2012-09-04 Cormatrix Cardiovascular, Inc. Prosthetic tissue valve
US8679176B2 (en) 2007-12-18 2014-03-25 Cormatrix Cardiovascular, Inc Prosthetic tissue valve
AU2012262549B2 (en) 2011-05-27 2016-02-11 Cormatrix Cardiovascular, Inc. Extracellular matrix material valve conduit and methods of making thereof
EP2713943A4 (en) * 2011-05-31 2014-12-17 Cormatrix Cardiovascular Inc Compositions for preventing cardiac arrhythmia
JP2023514080A (en) * 2020-02-04 2023-04-05 ヒエラバイオ インコーポレイテッド Intrapericardial infusion composition containing stem cells and use thereof
EP4281132A1 (en) * 2021-01-25 2023-11-29 North Carolina State University Compositions and methods for delivering therapeutics to the heart

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000016848A1 (en) * 1998-09-24 2000-03-30 C.R. Bard, Inc. Systems and methods for treating ischemia
WO2000044443A2 (en) * 1999-01-29 2000-08-03 Angiotech Pharmaceuticals Inc. Intra-pericardial delivery of anti-microtubule agents
US20070287683A1 (en) * 2006-05-25 2007-12-13 Momenta Pharmaceuticals, Inc. Low molecular weight heparin composition and uses thereof
WO2008091867A2 (en) * 2007-01-22 2008-07-31 Children's Medical Center Corporation Periostin induces proliferation of cardiomyocytes and promotes cardiac regeneration

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5681278A (en) * 1994-06-23 1997-10-28 Cormedics Corp. Coronary vasculature treatment method
US5797870A (en) * 1995-06-07 1998-08-25 Indiana University Foundation Pericardial delivery of therapeutic and diagnostic agents
US6283951B1 (en) * 1996-10-11 2001-09-04 Transvascular, Inc. Systems and methods for delivering drugs to selected locations within the body
US20030187460A1 (en) * 1999-08-10 2003-10-02 Chin Albert K. Methods and apparatus for endoscopic cardiac surgery
AU2002254158A1 (en) * 2001-03-08 2002-09-24 Volcano Therapeutics, Inc. Medical devices, compositions and methods for treating vulnerable plaque
US7195774B2 (en) * 2001-08-29 2007-03-27 Carvalho Ricardo Azevedo Ponte Implantable and sealable system for unidirectional delivery of therapeutic agents to tissues
US7229966B2 (en) * 2002-12-17 2007-06-12 Nastech Pharmaceutical Company Inc. Compositions and methods for enhanced mucosal delivery of Y2 receptor-binding peptides and methods for treating and preventing obesity
US20050208095A1 (en) * 2003-11-20 2005-09-22 Angiotech International Ag Polymer compositions and methods for their use
CN101248171B (en) * 2005-04-12 2015-11-25 迈索布拉斯特股份有限公司 By tissue non-specific alkaline phosphatase isolation of adult multipotential cells
US20070299043A1 (en) * 2005-10-03 2007-12-27 Hunter William L Anti-scarring drug combinations and use thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000016848A1 (en) * 1998-09-24 2000-03-30 C.R. Bard, Inc. Systems and methods for treating ischemia
WO2000044443A2 (en) * 1999-01-29 2000-08-03 Angiotech Pharmaceuticals Inc. Intra-pericardial delivery of anti-microtubule agents
US20070287683A1 (en) * 2006-05-25 2007-12-13 Momenta Pharmaceuticals, Inc. Low molecular weight heparin composition and uses thereof
WO2008091867A2 (en) * 2007-01-22 2008-07-31 Children's Medical Center Corporation Periostin induces proliferation of cardiomyocytes and promotes cardiac regeneration

Also Published As

Publication number Publication date
WO2011031299A1 (en) 2011-03-17
WO2011031301A2 (en) 2011-03-17

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