WO2011056390A3 - Method of making an artificial micro-gland that is anisotropic - Google Patents

Method of making an artificial micro-gland that is anisotropic Download PDF

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Publication number
WO2011056390A3
WO2011056390A3 PCT/US2010/052986 US2010052986W WO2011056390A3 WO 2011056390 A3 WO2011056390 A3 WO 2011056390A3 US 2010052986 W US2010052986 W US 2010052986W WO 2011056390 A3 WO2011056390 A3 WO 2011056390A3
Authority
WO
WIPO (PCT)
Prior art keywords
template
fluid
anisotropic
gland
making
Prior art date
Application number
PCT/US2010/052986
Other languages
French (fr)
Other versions
WO2011056390A2 (en
Inventor
Manuel Marquez
Samantha Marquez
Original Assignee
Manuel Marquez
Samantha Marquez
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Manuel Marquez, Samantha Marquez filed Critical Manuel Marquez
Publication of WO2011056390A2 publication Critical patent/WO2011056390A2/en
Publication of WO2011056390A3 publication Critical patent/WO2011056390A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02—Algae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system

Abstract

A method is disclosed for making an artificial micro-gland having a continuous anisotropic membrane of two or more types of living cells. A first step includes forming a carrier fluid in a microchannel in a laminar flow of two distinct fluid flows. Another step includes introducing a template, which may itself be anisotropic, into the microchannel in a manner such that the template straddles the interface between the first fluid-flow and the second fluid-flow. In some embodiments two types of living cells within the template are separately attracted one of the fluid flows by the presence of an agent of taxis. In other embodiments, cells within one or the other of the fluid flows are attracted to agents within the template. Membranes form on the template and join together to form a complete cellular membrane around a reservoir.
PCT/US2010/052986 2009-11-03 2010-10-16 Method of making an artificial micro-gland that is anisotropic WO2011056390A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US25766609P 2009-11-03 2009-11-03
US61/257,666 2009-11-03
US26082409P 2009-11-12 2009-11-12
US61/260,824 2009-11-12

Publications (2)

Publication Number Publication Date
WO2011056390A2 WO2011056390A2 (en) 2011-05-12
WO2011056390A3 true WO2011056390A3 (en) 2011-09-01

Family

ID=43970632

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/US2010/052986 WO2011056390A2 (en) 2009-11-03 2010-10-16 Method of making an artificial micro-gland that is anisotropic
PCT/US2010/052985 WO2011056389A2 (en) 2009-11-03 2010-10-16 Method of making an artificial micro-gland using taxis

Family Applications After (1)

Application Number Title Priority Date Filing Date
PCT/US2010/052985 WO2011056389A2 (en) 2009-11-03 2010-10-16 Method of making an artificial micro-gland using taxis

Country Status (1)

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WO (2) WO2011056390A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140335172A1 (en) * 2013-05-10 2014-11-13 The University Of Hong Kong Ophthalmological rinsing agent and methods therefof

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3993072A (en) * 1974-08-28 1976-11-23 Alza Corporation Microporous drug delivery device
US4378016A (en) * 1981-07-15 1983-03-29 Biotek, Inc. Artificial endocrine gland containing hormone-producing cells
US4923457A (en) * 1985-11-22 1990-05-08 Industrikontakt Ing. O. Ellingsen & Co. Artificial gland for implantation in a human body
US20030031696A1 (en) * 1999-02-24 2003-02-13 Baum Bruce J. Artificial salivary gland
US20060104957A1 (en) * 2004-11-15 2006-05-18 The Board of Louisiana State University and Agricultural and Mechanical College Bioartificial lacrimal gland

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2438856C (en) * 2001-02-23 2007-08-07 Japan Science And Technology Corporation Process and apparatus for producing emulsion and microcapsules
CA2599683A1 (en) * 2005-03-04 2006-09-14 President And Fellows Of Harvard College Method and apparatus for forming multiple emulsions
CN102014871A (en) * 2007-03-28 2011-04-13 哈佛大学 Emulsions and techniques for formation
WO2009048532A2 (en) * 2007-10-05 2009-04-16 President And Fellows Of Harvard College Formation of particles for ultrasound application, drug release, and other uses, and microfluidic methods of preparation

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3993072A (en) * 1974-08-28 1976-11-23 Alza Corporation Microporous drug delivery device
US4378016A (en) * 1981-07-15 1983-03-29 Biotek, Inc. Artificial endocrine gland containing hormone-producing cells
US4923457A (en) * 1985-11-22 1990-05-08 Industrikontakt Ing. O. Ellingsen & Co. Artificial gland for implantation in a human body
US20030031696A1 (en) * 1999-02-24 2003-02-13 Baum Bruce J. Artificial salivary gland
US20060104957A1 (en) * 2004-11-15 2006-05-18 The Board of Louisiana State University and Agricultural and Mechanical College Bioartificial lacrimal gland

Also Published As

Publication number Publication date
WO2011056390A2 (en) 2011-05-12
WO2011056389A3 (en) 2011-09-01
WO2011056389A2 (en) 2011-05-12

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