WO2011111027A3 - Oral dispersible delayed release tablet formulation - Google Patents
Oral dispersible delayed release tablet formulation Download PDFInfo
- Publication number
- WO2011111027A3 WO2011111027A3 PCT/IB2011/051031 IB2011051031W WO2011111027A3 WO 2011111027 A3 WO2011111027 A3 WO 2011111027A3 IB 2011051031 W IB2011051031 W IB 2011051031W WO 2011111027 A3 WO2011111027 A3 WO 2011111027A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- tablet
- delayed release
- mini
- release tablet
- tablet formulation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
Abstract
A formulation for delivery of a therapeutic agent to the small intestine which features a combination of a single delayed release mini-tablet for delivery to the gastrointestinal tract, surrounded by a fast disintegrating tablet layer which dissolves in the oral cavity. The oral disintegrating tablet which undergoes rapid disintegration in the oral cavity supports ease of swallowing and hence ease of administration of the mini-tablet, which is responsible for delayed release of a therapeutic agent in the small intestine. The mini-tablet preferably has a relatively small diameter, smaller than that of a regular tablet.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US31272210P | 2010-03-11 | 2010-03-11 | |
US61/312,722 | 2010-03-11 | ||
US33416410P | 2010-05-12 | 2010-05-12 | |
US61/334,164 | 2010-05-12 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2011111027A2 WO2011111027A2 (en) | 2011-09-15 |
WO2011111027A3 true WO2011111027A3 (en) | 2012-03-01 |
Family
ID=44483952
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IB2011/051031 WO2011111027A2 (en) | 2010-03-11 | 2011-03-11 | Oral dispersible delayed release tablet formulation |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2011111027A2 (en) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8808736B2 (en) | 2011-02-11 | 2014-08-19 | Zx Pharma, Llc | Enteric coated multiparticulate controlled release peppermint oil composition and related methods |
CA2826889C (en) | 2011-02-11 | 2016-12-20 | Zx Pharma, Llc | Multiparticulate l-menthol formulations and related methods |
US8911780B2 (en) | 2011-02-11 | 2014-12-16 | Zx Pharma, Llc | Multiparticulate L-menthol formulations and related methods |
CN105263480B (en) * | 2013-04-23 | 2018-08-28 | Zx制药有限责任公司 | The multiparticulates controlled release mint oil combination object and correlation technique of enteric coating |
CN103556501B (en) * | 2013-10-30 | 2015-06-24 | 齐齐哈尔大学 | Cation dyeing auxiliary of linen reactive dye, preparation method and application of cation dyeing auxiliary |
KR102392313B1 (en) * | 2014-09-03 | 2022-05-02 | 라이온 가부시키가이샤 | Coated preparation and method for producing same |
US20170042806A1 (en) | 2015-04-29 | 2017-02-16 | Dexcel Pharma Technologies Ltd. | Orally disintegrating compositions |
KR102279993B1 (en) | 2015-09-23 | 2021-07-21 | 엑스더블유파마 리미티드 | Precursors of gamma-hydroxybutyric acid and compositions and uses thereof |
US10076494B2 (en) | 2016-06-16 | 2018-09-18 | Dexcel Pharma Technologies Ltd. | Stable orally disintegrating pharmaceutical compositions |
CN110724279B (en) * | 2019-10-14 | 2022-04-22 | 浙江海洋大学 | Preparation method of guar gum/starch composite hydrogel sensitive to temperature and pH |
CN112156077B (en) * | 2020-10-26 | 2023-01-24 | 上海纳为生物技术有限公司 | N-acetylglucosamine tablet and preparation method thereof |
CA3201490A1 (en) * | 2020-11-13 | 2022-05-19 | Sila Srl | Orally dispersible compound containing an ester or salt of n-butyric acid and process for production |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020142034A1 (en) * | 1998-05-18 | 2002-10-03 | Toshihiro Shimizu | Orally disintegrable tablets |
EP1430888A1 (en) * | 2001-09-28 | 2004-06-23 | Sanwa Kagaku Kenkyusho Co., Ltd. | Press-coated molded article undergoing quick disintegration |
WO2007075980A2 (en) * | 2005-12-20 | 2007-07-05 | Teva Pharmaceutical Industries Ltd. | Lansoprazole orally disintegrating tablets |
WO2009060064A2 (en) * | 2007-11-09 | 2009-05-14 | Valpharma S.A. | Pharmaceutical formulations for the oral administration of ppi |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0181966A1 (en) | 1984-11-13 | 1986-05-28 | Gist-Brocades N.V. | Compression-coated dispersible tablets |
US6709678B2 (en) | 1996-08-15 | 2004-03-23 | Losan Pharma Gmbh | Easy to swallow oral medicament composition |
US20040068000A1 (en) | 2002-10-02 | 2004-04-08 | Mintong Guo | Compression coated tablets |
US20070077300A1 (en) | 2005-09-30 | 2007-04-05 | Wynn David W | Oral compositions containing a salivation inducing agent |
FR2894475B1 (en) | 2005-12-14 | 2008-05-16 | Servier Lab | ORODISPERSIBLE PHARMACEUTICAL COMPOSITION FOR OROMUCOSAL OR SUBLINGUAL ADMINISTRATION OF AGOMELATIN |
AU2007266574A1 (en) | 2006-06-01 | 2007-12-06 | Dexcel Pharma Technologies Ltd. | Multiple unit pharmaceutical formulation |
ITMI20062290A1 (en) | 2006-11-28 | 2008-05-29 | Monteres S R L | TABLETS STABLE WITH STORAGE BASED ON BENZIMIDAZOLE DERIVATIVES COATED WITH GASTRO-RESISTANT FILM |
-
2011
- 2011-03-11 WO PCT/IB2011/051031 patent/WO2011111027A2/en active Application Filing
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020142034A1 (en) * | 1998-05-18 | 2002-10-03 | Toshihiro Shimizu | Orally disintegrable tablets |
EP1430888A1 (en) * | 2001-09-28 | 2004-06-23 | Sanwa Kagaku Kenkyusho Co., Ltd. | Press-coated molded article undergoing quick disintegration |
WO2007075980A2 (en) * | 2005-12-20 | 2007-07-05 | Teva Pharmaceutical Industries Ltd. | Lansoprazole orally disintegrating tablets |
WO2009060064A2 (en) * | 2007-11-09 | 2009-05-14 | Valpharma S.A. | Pharmaceutical formulations for the oral administration of ppi |
Also Published As
Publication number | Publication date |
---|---|
WO2011111027A2 (en) | 2011-09-15 |
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