WO2011135530A3 - Device for delivery of rheumatoid arthritis medication - Google Patents

Device for delivery of rheumatoid arthritis medication Download PDF

Info

Publication number
WO2011135530A3
WO2011135530A3 PCT/IB2011/051861 IB2011051861W WO2011135530A3 WO 2011135530 A3 WO2011135530 A3 WO 2011135530A3 IB 2011051861 W IB2011051861 W IB 2011051861W WO 2011135530 A3 WO2011135530 A3 WO 2011135530A3
Authority
WO
WIPO (PCT)
Prior art keywords
structures
rheumatoid arthritis
microneedles
delivery
pattern
Prior art date
Application number
PCT/IB2011/051861
Other languages
French (fr)
Other versions
WO2011135530A2 (en
Inventor
Russell Frederick Ross
Original Assignee
Kimberly-Clark Worldwide, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to DK11774518.2T priority Critical patent/DK2563450T3/en
Application filed by Kimberly-Clark Worldwide, Inc. filed Critical Kimberly-Clark Worldwide, Inc.
Priority to AU2011246879A priority patent/AU2011246879C1/en
Priority to MX2012012437A priority patent/MX345837B/en
Priority to KR1020127030831A priority patent/KR101799612B1/en
Priority to CA2797204A priority patent/CA2797204C/en
Priority to RU2012150728/14A priority patent/RU2585159C2/en
Priority to EP11774518.2A priority patent/EP2563450B1/en
Priority to CN201180032076.7A priority patent/CN102971037B/en
Priority to US13/641,501 priority patent/US9522263B2/en
Priority to JP2013506796A priority patent/JP5860032B2/en
Priority to ES11774518.2T priority patent/ES2636673T3/en
Publication of WO2011135530A2 publication Critical patent/WO2011135530A2/en
Publication of WO2011135530A3 publication Critical patent/WO2011135530A3/en
Priority to AU2015271878A priority patent/AU2015271878B2/en
Priority to US15/378,097 priority patent/US10029082B2/en
Priority to US16/040,714 priority patent/US10709884B2/en
Priority to US16/896,941 priority patent/US11565098B2/en
Priority to US18/148,025 priority patent/US20230137871A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/003—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0061—Methods for using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00—Metal working
    • Y10T29/49—Method of mechanical manufacture

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Medical Informatics (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Surgery (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Moulds For Moulding Plastics Or The Like (AREA)

Abstract

Disclosed are devices for delivering a rheumatoid arthritis drug across a dermal barrier. The devices include microneedles for penetrating the stratum corneum and also include structures fabricated on a surface of the microneedles to form a nanotopography. A random or non-random pattern of structures may be fabricated such as a complex pattern including structures of differing sizes and/or shapes. The pattern of structures on the surface of the microneedles may include nano-sized structures.
PCT/IB2011/051861 2010-04-28 2011-04-27 Device for delivery of rheumatoid arthritis medication WO2011135530A2 (en)

Priority Applications (16)

Application Number Priority Date Filing Date Title
CN201180032076.7A CN102971037B (en) 2010-04-28 2011-04-27 For sending the device of medicine for treating rheumatoid arthritis
EP11774518.2A EP2563450B1 (en) 2010-04-28 2011-04-27 Device for delivery of rheumatoid arthritis medication
AU2011246879A AU2011246879C1 (en) 2010-04-28 2011-04-27 Device for delivery of rheumatoid arthritis medication
MX2012012437A MX345837B (en) 2010-04-28 2011-04-27 Device for delivery of rheumatoid arthritis medication.
KR1020127030831A KR101799612B1 (en) 2010-04-28 2011-04-27 Device for delivery of rheumatoid arthritis medication
CA2797204A CA2797204C (en) 2010-04-28 2011-04-27 Device for delivery of rheumatoid arthritis medication
RU2012150728/14A RU2585159C2 (en) 2010-04-28 2011-04-27 Device for delivering drug used in rheumatoid arthritis
DK11774518.2T DK2563450T3 (en) 2010-04-28 2011-04-27 Apparatus for administering rheumatoid arthritis drug
ES11774518.2T ES2636673T3 (en) 2010-04-28 2011-04-27 Device for the administration of rheumatoid arthritis medications
JP2013506796A JP5860032B2 (en) 2010-04-28 2011-04-27 Device for the delivery of rheumatoid arthritis drugs
US13/641,501 US9522263B2 (en) 2010-04-28 2011-04-27 Device for delivery of rheumatoid arthritis medication
AU2015271878A AU2015271878B2 (en) 2010-04-28 2015-12-17 Device for delivery of rheumatoid arthritis medication
US15/378,097 US10029082B2 (en) 2010-04-28 2016-12-14 Device for delivery of rheumatoid arthritis medication
US16/040,714 US10709884B2 (en) 2010-04-28 2018-07-20 Device for delivery of rheumatoid arthritis medication
US16/896,941 US11565098B2 (en) 2010-04-28 2020-06-09 Device for delivery of rheumatoid arthritis medication
US18/148,025 US20230137871A1 (en) 2010-04-28 2022-12-29 Device for delivery of rheumatoid arthritis medication

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US32872310P 2010-04-28 2010-04-28
US61/328,723 2010-04-28
US41110110P 2010-11-08 2010-11-08
US61/411,101 2010-11-08
US201161435973P 2011-01-25 2011-01-25
US61/435,973 2011-01-25

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US13/641,501 A-371-Of-International US9522263B2 (en) 2010-04-28 2011-04-27 Device for delivery of rheumatoid arthritis medication
US15/378,097 Continuation US10029082B2 (en) 2010-04-28 2016-12-14 Device for delivery of rheumatoid arthritis medication

Publications (2)

Publication Number Publication Date
WO2011135530A2 WO2011135530A2 (en) 2011-11-03
WO2011135530A3 true WO2011135530A3 (en) 2012-03-15

Family

ID=44861972

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2011/051861 WO2011135530A2 (en) 2010-04-28 2011-04-27 Device for delivery of rheumatoid arthritis medication

Country Status (13)

Country Link
US (5) US9522263B2 (en)
EP (1) EP2563450B1 (en)
JP (1) JP5860032B2 (en)
KR (1) KR101799612B1 (en)
CN (1) CN102971037B (en)
AU (1) AU2011246879C1 (en)
CA (1) CA2797204C (en)
DK (1) DK2563450T3 (en)
ES (1) ES2636673T3 (en)
MX (1) MX345837B (en)
PT (1) PT2563450T (en)
RU (1) RU2585159C2 (en)
WO (1) WO2011135530A2 (en)

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