WO2012015248A2 - Apparatus for generating high intensity focused ultrasound - Google Patents

Apparatus for generating high intensity focused ultrasound Download PDF

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Publication number
WO2012015248A2
WO2012015248A2 PCT/KR2011/005552 KR2011005552W WO2012015248A2 WO 2012015248 A2 WO2012015248 A2 WO 2012015248A2 KR 2011005552 W KR2011005552 W KR 2011005552W WO 2012015248 A2 WO2012015248 A2 WO 2012015248A2
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WO
WIPO (PCT)
Prior art keywords
focused ultrasound
diagnostic
ultrasound
focused
housing
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PCT/KR2011/005552
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French (fr)
Korean (ko)
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WO2012015248A3 (en
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조성찬
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Cho Sung Chan
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Priority to CN2011800373389A priority Critical patent/CN103052426A/en
Publication of WO2012015248A2 publication Critical patent/WO2012015248A2/en
Publication of WO2012015248A3 publication Critical patent/WO2012015248A3/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/44Constructional features of the ultrasonic, sonic or infrasonic diagnostic device
    • A61B8/4444Constructional features of the ultrasonic, sonic or infrasonic diagnostic device related to the probe
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00Ultrasound therapy
    • A61N7/02Localised ultrasound hyperthermia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/36Image-producing devices or illumination devices not otherwise provided for
    • A61B90/37Surgical systems with images on a monitor during operation
    • A61B2090/378Surgical systems with images on a monitor during operation using ultrasound
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00Ultrasound therapy
    • A61N2007/0056Beam shaping elements
    • A61N2007/0065Concave transducers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00Ultrasound therapy
    • A61N2007/0078Ultrasound therapy with multiple treatment transducers

Definitions

  • the present invention relates to a focused ultrasound generating apparatus capable of focused ultrasound therapy while performing a diagnostic function through real-time image confirmation by generating a diagnostic ultrasound and a focused ultrasound.
  • Focused ultrasound therapy techniques for focusing ultrasound and using high intensity focused ultrasound to treat a patient's affected area or for skin beauty are known. This focused ultrasound therapy is performed by a focused ultrasound generating apparatus using a focused ultrasound transducer that focuses the ultrasound to generate a high intensity focused ultrasound.
  • an apparatus for adding an ultrasound diagnosis function to a focused ultrasound generating device has been introduced to perform an image diagnosis on a treatment target while performing focused ultrasound therapy.
  • a focused ultrasound generating apparatus having a diagnostic function in which a diagnostic ultrasound transducer for generating diagnostic ultrasound is integrally formed in a focused ultrasound generating apparatus has been developed.
  • Miniaturization is essential in order to utilize the focused ultrasound generating device having such a diagnosis function for skin cosmetic procedures, and conventionally, a method of acquiring an image for positioning is inserted by inserting a diagnostic ultrasound transducer of a single element into the center of the focused ultrasound transducer. It was.
  • the present invention has been made to solve the problems as described above, and the problem to be solved by the present invention is to provide an economically efficient focused ultrasound generating device having an ultrasound generating function for real-time diagnostic image acquisition.
  • a focused ultrasound generating device having a diagnostic function is a housing (housing), an ultrasonic transducer installed in the housing and generating a diagnostic ultrasound, and is installed in the housing
  • HIFU high intensity focused ultrasound
  • the diagnostic ultrasound transducer may be installed to be detachable from the housing.
  • the diagnostic ultrasound transducer may be a 2D ultrasound transducer.
  • the plurality of focused ultrasound transducers may be installed in front of the diagnostic ultrasound transducer so as to be spaced apart from each other so as to form an area through which the ultrasound generated by the diagnostic ultrasound transducer passes forward.
  • the plurality of focused ultrasound transducers may be arranged radially at equal intervals.
  • the plurality of focused ultrasound transducers may be arranged such that the generated focused ultrasounds have a common focus.
  • a diagnostic ultrasound transducer for acquiring a diagnostic image and a focused ultrasound transducer for generating therapeutic focused ultrasound are provided, but the diagnostic ultrasound transducer is installed in a detachable state.
  • the ultrasound transducer for acquiring the diagnostic image can be separated and reused, a focused ultrasound generation apparatus with improved diagnostic efficiency and economic efficiency is provided.
  • a plurality of focused ultrasound transducers may be used to generate high intensity focused ultrasound similarly or identically to a single focused ultrasound transducer.
  • FIG. 1 is a schematic diagram of a focused ultrasound generating apparatus according to an embodiment of the present invention.
  • FIG. 2 is a view showing the arrangement relationship between the ultrasound transducer and the focused ultrasound transducer of the focused ultrasound generation apparatus according to an embodiment of the present invention.
  • FIG. 3 is a diagram illustrating an arrangement relationship between an ultrasound transducer and a focused ultrasound transducer of a focused ultrasound generating apparatus according to another exemplary embodiment of the present invention.
  • FIG. 5 is a view for explaining a state in which the diagnostic ultrasound transducer is installed in the housing of the focused ultrasound generation device according to another embodiment of the present invention.
  • FIG. 6 is a block diagram illustrating a control relationship of the focused ultrasound generating apparatus according to the exemplary embodiment of the present invention.
  • the focused ultrasound generating apparatus includes a housing 40.
  • the housing 40 has a form in which the tip thereof is opened to form an opening, and the treatment window 41 is installed in the opening.
  • the diagnostic ultrasound transducer 20 is installed inside the housing 10 and generates diagnostic ultrasound.
  • the diagnostic ultrasound transducer 20 may be a conventional ultrasound transducer that generates diagnostic ultrasound for acquiring a diagnostic image, and is installed inside the housing 40 to allow the generated diagnostic ultrasound to move forward of the housing 40.
  • a plurality of focused ultrasound transducers 30 are installed in the housing 40, and the focused ultrasound transducers 30 generate high intensity focused ultrasound (HIFU).
  • the plurality of focused ultrasound transducers 30 may be implemented as a conventional focused ultrasound transducer that generates focused ultrasound.
  • FIG. 4 is a simulation result of the generation of high intensity focused ultrasound using the focused ultrasound generation apparatus according to the embodiment of the present invention.
  • a single focused ultrasound transducer is used even if the focused ultrasounds of two focused ultrasound transducers are generated at the same point to generate focused ultrasounds.
  • the same effect occurs as to generate high intensity focused ultrasound.
  • This can effectively generate high intensity focused ultrasound in an environment in which it is difficult to use a single focused ultrasound transducer due to various factors, such as when the focused ultrasound transducers are spaced apart to obtain a diagnostic ultrasound image, as in the exemplary embodiment of the present invention.
  • the plurality of focused ultrasound transducers 30 may be installed on the support 10 fixed inside the housing 40.
  • An opening 11 is formed at the tip of the support 10, and a plurality of ultrasonic transducers 30 may be disposed around the opening 11.
  • the diagnostic ultrasound transducer 20 may be disposed behind the ultrasound transducer 30, wherein the diagnostic ultrasound generated by the diagnostic ultrasound transducer 20 is the opening of the support 10 It passes through (11) and advances forward.
  • the diagnostic ultrasound transducer 20 is installed in a detachable state in the housing 40.
  • the diagnostic ultrasound transducer 20 may be installed in a manner passing through the center of the housing 40. That is, referring to FIG. 4, the through hole 43 may be formed in the housing 40 in the lateral direction, and the diagnostic ultrasound transducer 20 may be inserted into the through hole 43.
  • the diagnostic ultrasonic transducer 20 may be formed to be discharged again through the through hole 43, and thus may be detachably installed in the case 40.
  • the support 10 is also formed with a through hole 13 (shown in FIG. 1) through which the diagnostic ultrasonic transducer 20 is inserted. The diagnostic ultrasound transducer 20 is inserted into the through hole 43 of the housing 40 and the through hole 13 of the support 10 in a detachable state.
  • the focused ultrasound transducer 30 Since the focused ultrasound transducer 30 is installed in the housing 40 in a detachable state, the focused ultrasound transducer 30, which has a relatively short lifespan, is shorter than the diagnostic ultrasound transducer 20 that generates diagnostic ultrasound. In this case, by separating and reusing the diagnostic ultrasound transducer 20 and replacing the focused ultrasound transducer 30 and the housing 40, the diagnostic ultrasound transducer 20 may be reused to implement a new focused ultrasound generating device. Can be greatly improved.
  • the support 10 on which the focused ultrasound transducer 30 is installed, and the diagnostic ultrasound transducer 20 may be installed to be movable in the housing 40. Accordingly, the procedure can be performed while moving the treatment and diagnosis site.
  • FIG. 1 is shown a case of two focused ultrasound transducer 30, the focused ultrasound transducer 30 may be provided with three or more.
  • the plurality of focused ultrasound transducers 30 are diagnosed so as to be spaced apart from each other so as to form an area A through which ultrasonic waves generated by the diagnostic ultrasound transducer 20 pass forward. It may be disposed in front of the ultrasonic transducer 20. In addition, the plurality of focused ultrasound transducers 30 may be arranged radially at equal intervals. For example, referring to FIGS. 1 and 2, when the two focused ultrasound transducers 30 are provided, the two focused ultrasound transducers may be disposed at intervals of 180 degrees while being spaced apart from each other by a predetermined distance.
  • the three focused ultrasound transducers 30 are spaced 90 degrees apart from each other by a predetermined distance. It can be arranged as.
  • the four focused ultrasound transducers 30 may be arranged to focus the focused ultrasound at a common focal point.
  • the number of focused ultrasound transducers 30 is not limited to two or four but may be provided as three or five or more.
  • the plurality of focused ultrasound transducers 30 may be arranged such that the focused ultrasounds generated by each have a common focal point F.
  • FIG. The focused ultrasounds generated by the plurality of focused ultrasound transducers 30 are focused at the same point to generate heat, which can be used for treatment.
  • the focal point F of the focused ultrasound generated by the focused ultrasound transducer 30 may be positioned outside the treatment window 41.
  • the ultrasound generated by the diagnostic ultrasound transducer 20 is irradiated to the body in the same direction as the focused ultrasound through the front end of the housing 40.
  • the diagnostic ultrasound may be formed to coincide with the treatment position of the focused ultrasound. Accordingly, during the treatment using the focused ultrasound, the treatment site may be examined in real time using the diagnostic ultrasound.
  • the diagnostic ultrasound transducer 20 may be a 2D ultrasound transducer. If the diagnostic ultrasound transducer 20 is a 2D ultrasound transducer, diagnostic images may be obtained in real time by improving diagnostic efficiency, and a housing including a plurality of focused ultrasound transducers 30 may be used even if a relatively expensive 2D ultrasound transducer is used. Since the 10 can be detachably detached, the diagnostic ultrasound transducer 20 can be recovered after separation and replaced along only the focused ultrasound transducer 30, thereby preventing the 2D ultrasound transducer from being disposed together with the focused ultrasound transducer 30. Therefore, economic feasibility can be secured.
  • the interior of the housing 40 may have a space filled with water or an ultrasonic delivery medium.
  • desaturation may be performed to remove bubbles in the water to improve ultrasonic attenuation and delivery characteristics of the filled water or the ultrasonic delivery medium.
  • the interior of the housing 40 may be sealed to be filled with water or an ultrasonic delivery medium, and the front end of the housing 40 and the surface in close contact with the diagnostic ultrasonic transducer 20 may be formed of a material having less attenuation of ultrasonic waves. have.
  • the focused ultrasound generating apparatus controls the first control unit 51 and the focused ultrasound transducer 30 that control the diagnostic ultrasound transducer 20 that generates the diagnostic ultrasound.
  • the second control unit 53 and the system control unit 55 for controlling the first control unit 51 and the second control unit 53 as a whole.
  • a monitor 57 displaying an image acquired by the diagnostic ultrasound transducer 20 may be connected to the first control unit 51.
  • the control units 51, 53, 55 include a microprocessor, memory, and associated hardware and software, and may be configured to perform a control algorithm in accordance with predetermined logic.
  • the present invention relates to a focused ultrasound generating device can be applied to medical devices and the like, there is industrial applicability.

Abstract

An apparatus for generating high intensity focused ultrasound (HIFU) includes: a housing; an ultrasonic transducer which is provided inside the housing and generates a diagnostic ultrasound; and a plurality of HIFU transducers which are provided in the housing and generates the HIFU. The apparatus for generating the HIFU includes the ultrasonic transducer for acquiring diagnostic images and the HIFU-generating transducers, which have a relatively short life and which can be exchanged at the end of their lifespan without exchanging the ultrasonic transducer since the HIFU transducers have a separate structure, allow for performance of a diagnostic function and simultaneously improve economic efficiency.

Description

집속 초음파 생성 장치Focused ultrasound generator
본 발명은 진단용 초음파 및 집속 초음파를 생성함으로써 실시간 영상 확인을 통한 진단 기능을 수행하면서 집속 초음파 치료가 가능한 집속 초음파 생성 장치에 관한 것이다.The present invention relates to a focused ultrasound generating apparatus capable of focused ultrasound therapy while performing a diagnostic function through real-time image confirmation by generating a diagnostic ultrasound and a focused ultrasound.
초음파를 집속하여 고강도의 집속 초음파(high intensity focused ultrasound)를 이용하여 환자의 환부를 치료하거나 피부 미용 등에 이용하는 집속 초음파 치료 기술이 알려져 있다. 이러한 집속 초음파 치료는 초음파를 집속하여 고강도의 집속 초음파를 생성하는 집속 초음파 변환기를 이용하는 집속 초음파 생성 장치에 의해 수행된다.BACKGROUND ART Focused ultrasound therapy techniques for focusing ultrasound and using high intensity focused ultrasound to treat a patient's affected area or for skin beauty are known. This focused ultrasound therapy is performed by a focused ultrasound generating apparatus using a focused ultrasound transducer that focuses the ultrasound to generate a high intensity focused ultrasound.
한편, 집속 초음파 치료를 진행하면서 치료 대상에 대한 영상 진단을 하기 위해 집속 초음파 생성 장치에 초음파 진단 기능을 부가하는 장치가 소개된 바 있다. 종래에 집속 초음파 생성 장치에 진단용 초음파를 생성하는 진단용 초음파 변환기를 일체로 형성한 진단 기능을 가지는 집속 초음파 생성 장치가 개발되었다.Meanwhile, an apparatus for adding an ultrasound diagnosis function to a focused ultrasound generating device has been introduced to perform an image diagnosis on a treatment target while performing focused ultrasound therapy. Conventionally, a focused ultrasound generating apparatus having a diagnostic function in which a diagnostic ultrasound transducer for generating diagnostic ultrasound is integrally formed in a focused ultrasound generating apparatus has been developed.
이러한 진단 기능을 가지는 집속 초음파 생성 장치를 피부 미용 시술 등에 활용하기 위해서는 소형화가 필수적이며, 종래에는 단일 소자의 진단용 초음파 변환기를 집속 초음파 변환기의 중앙에 삽입하여 위치 확인을 위한 이미지를 획득하는 방식을 취하였다.Miniaturization is essential in order to utilize the focused ultrasound generating device having such a diagnosis function for skin cosmetic procedures, and conventionally, a method of acquiring an image for positioning is inserted by inserting a diagnostic ultrasound transducer of a single element into the center of the focused ultrasound transducer. It was.
그러나, 단일 소자의 진단용 초음파 변환기를 이용하는 집속 초음파 생성 장치의 경우, A-모드 영상만을 획득할 수 있기 때문에 치료 부위가 넓을 경우 개별적으로 이미지를 획득하여 저장된 정지 영상만을 구현할 수 있고, 또한 이를 위해 별도의 이미지 처리 장치가 개발되어야 하며, 특히 치료에 필요한 실시간 이미지를 확보하는 것은 불가능하였다.However, in the case of a focused ultrasound generating apparatus using a diagnostic ultrasound transducer of a single device, since only the A-mode image can be obtained, only a still image stored by separately obtaining an image can be implemented when the treatment area is large, and for this purpose, Of the image processing apparatus had to be developed, and in particular it was impossible to obtain a real-time image for the treatment.
반면, 실시간 2D 단면 영상을 얻기 위해서는 어레이(array) 초음파 변환기를 집속 초음파 변환기의 중심부에 삽입해야 하는데, 이 경우 제품의 제조 비용이 크게 증가하여 경제성이 떨어지는 문제가 있다. 특히 집속 초음파 변환기의 수명이 제한되어 있기 때문에, 집속 초음파 변환기의 수명이 다한 경우, 상대적으로 수명이 길어 사용 가능한 진단용 어레이 초음파 변환기가 일체로 형성된 집속 초음파 변환기와 함께 폐기되어야 하기 때문에 경제적으로 매우 비효율적이다.On the other hand, in order to obtain a real-time 2D cross-sectional image it is necessary to insert the array (array) ultrasound transducer in the center of the focused ultrasound transducer, in this case there is a problem that the manufacturing cost of the product is greatly increased and economic efficiency is lowered. In particular, since the life of the focused ultrasound transducer is limited, it is economically very inefficient when the life of the focused ultrasound transducer is relatively long, which means that the diagnostic array ultrasound transducer that can be used must be disposed together with the integrally configured focused ultrasound transducer. .
본 발명은 전술한 바와 같은 문제점들을 해결하기 위해 창출된 것으로서, 본 발명이 해결하려는 과제는 실시간 진단 영상 획득을 위한 초음파 생성 기능을 가지면서도 경제적으로 효율적인 집속 초음파 생성 장치를 제공하는 것이다.SUMMARY OF THE INVENTION The present invention has been made to solve the problems as described above, and the problem to be solved by the present invention is to provide an economically efficient focused ultrasound generating device having an ultrasound generating function for real-time diagnostic image acquisition.
상기한 과제를 달성하기 위한 본 발명의 한 실시예에 따른 진단 기능을 구비하는 집속 초음파 생성 장치는, 하우징(housing), 상기 하우징에 설치되며 진단용 초음파를 생성하는 초음파 변환기, 그리고 상기 하우징에 설치되어 집속 초음파(high intensity focused ultrasound, HIFU)를 생성하는 복수의 집속 초음파 변환기를 포함한다.A focused ultrasound generating device having a diagnostic function according to an embodiment of the present invention for achieving the above object is a housing (housing), an ultrasonic transducer installed in the housing and generating a diagnostic ultrasound, and is installed in the housing A plurality of focused ultrasound transducers for generating high intensity focused ultrasound (HIFU).
상기 진단용 초음파 변환기는 상기 하우징에 탈착 가능한 상태로 설치될 수 있다.The diagnostic ultrasound transducer may be installed to be detachable from the housing.
상기 진단용 초음파 변환기는 2D 초음파 변환기일 수 있다.The diagnostic ultrasound transducer may be a 2D ultrasound transducer.
상기 복수의 집속 초음파 변환기는 상기 진단용 초음파 변환기에서 생성되어 전방으로 진행하는 초음파가 통과하는 영역을 형성하도록 서로 이격된 상태로 배치되도록 상기 진단용 초음파 변환기의 전방에 설치될 수 있다.The plurality of focused ultrasound transducers may be installed in front of the diagnostic ultrasound transducer so as to be spaced apart from each other so as to form an area through which the ultrasound generated by the diagnostic ultrasound transducer passes forward.
상기 복수의 집속 초음파 변환기는 방사상으로 등간격으로 배치될 수 있다.The plurality of focused ultrasound transducers may be arranged radially at equal intervals.
복수의 집속 초음파 변환기는 생성된 집속 초음파가 공통된 초점을 가지도록 배열될 수 있다.The plurality of focused ultrasound transducers may be arranged such that the generated focused ultrasounds have a common focus.
본 발명에 의하면, 진단 영상 획득을 위한 진단용 초음파 변환기와 치료용 집속 초음파 생성을 위한 집속 초음파 변환기를 구비하되 진단용 초음파 변환기가 탈착 가능한 상태로 설치됨으로써, 상대적으로 수명이 짧은 집속 초음파 변환기의 수명이 다한 경우에 진단 영상 획득을 위한 초음파 변환기를 분리하여 재사용할 수 있기 때문에, 진단 기능을 구현함과 동시에 경제적 효율성이 향상된 집속 초음파 생성 장치가 제공된다.According to the present invention, a diagnostic ultrasound transducer for acquiring a diagnostic image and a focused ultrasound transducer for generating therapeutic focused ultrasound are provided, but the diagnostic ultrasound transducer is installed in a detachable state. In this case, since the ultrasound transducer for acquiring the diagnostic image can be separated and reused, a focused ultrasound generation apparatus with improved diagnostic efficiency and economic efficiency is provided.
또한 복수의 집속 초음파 변환기를 이용하여 단일 집속 초음파 변환기와 유사하거나 동일하게 고강도 집속 초음파를 생성할 수 있다.In addition, a plurality of focused ultrasound transducers may be used to generate high intensity focused ultrasound similarly or identically to a single focused ultrasound transducer.
도 1은 본 발명의 실시예에 따른 집속 초음파 생성 장치의 개략도이다.1 is a schematic diagram of a focused ultrasound generating apparatus according to an embodiment of the present invention.
도 2는 본 발명의 실시예에 따른 집속 초음파 생성 장치의 초음파 변환기와 집속 초음파 변환기의 배열 관계를 보여주는 도면이다.2 is a view showing the arrangement relationship between the ultrasound transducer and the focused ultrasound transducer of the focused ultrasound generation apparatus according to an embodiment of the present invention.
도 3은 본 발명의 다른 실시예에 따른 집속 초음파 생성 장치의 초음파 변환기와 집속 초음파 변환기의 배열 관계를 보여주는 도면이다.3 is a diagram illustrating an arrangement relationship between an ultrasound transducer and a focused ultrasound transducer of a focused ultrasound generating apparatus according to another exemplary embodiment of the present invention.
도 4는 본 발명의 실시예에 따른 집속 초음파 생성 장치를 이용한 고강도 집속 초음파 생성을 시뮬레이션한 결과이다.4 is a simulation result of the generation of high intensity focused ultrasound using the focused ultrasound generation apparatus according to the embodiment of the present invention.
도 5는 본 발명의 다른 실시예에 따른 집속 초음파 생성 장치의 하우징에 진단용 초음파 변환기가 설치되는 상태를 설명하기 위한 도면이다.5 is a view for explaining a state in which the diagnostic ultrasound transducer is installed in the housing of the focused ultrasound generation device according to another embodiment of the present invention.
도 6은 본 발명의 실시예에 따른 집속 초음파 생성 장치의 제어 관계를 설명하기 위한 블록도이다.6 is a block diagram illustrating a control relationship of the focused ultrasound generating apparatus according to the exemplary embodiment of the present invention.
이하에서 본 발명의 실시예를 첨부된 도면을 참조로 상세히 설명한다.Hereinafter, embodiments of the present invention will be described in detail with reference to the accompanying drawings.
도 1을 참조하면, 본 발명의 실시예에 따른 집속 초음파 생성 장치는 하우징(housing)(40)을 포함한다. 하우징(40)은 그 선단이 개방되어 개구(opening)를 형성하는 형태를 가지며 이 개구에는 치료 윈도우(41)가 설치된다.Referring to FIG. 1, the focused ultrasound generating apparatus according to an exemplary embodiment of the present invention includes a housing 40. The housing 40 has a form in which the tip thereof is opened to form an opening, and the treatment window 41 is installed in the opening.
진단용 초음파 변환기(20)가 하우징(10)의 내부에 설치되며 진단용 초음파를 생성한다. 진단용 초음파 변환기(20)는 진단용 이미지 획득을 위한 진단용 초음파를 생성하는 통상의 초음파 변환기일 수 있으며, 생성된 진단용 초음파가 하우징(40)의 전방으로 나아갈 수 있도록 하우징(40)의 내부에 설치된다.The diagnostic ultrasound transducer 20 is installed inside the housing 10 and generates diagnostic ultrasound. The diagnostic ultrasound transducer 20 may be a conventional ultrasound transducer that generates diagnostic ultrasound for acquiring a diagnostic image, and is installed inside the housing 40 to allow the generated diagnostic ultrasound to move forward of the housing 40.
복수의 집속 초음파 변환기(30)가 하우징(40)에 설치되며, 집속 초음파 변환기(30)는 집속 초음파(high intensity focused ultrasound, HIFU)를 생성한다. 복수의 집속 초음파 변환기(30)는 집속 초음파를 생성하는 종래의 집속 초음파 변환기로 구현될 수 있다.A plurality of focused ultrasound transducers 30 are installed in the housing 40, and the focused ultrasound transducers 30 generate high intensity focused ultrasound (HIFU). The plurality of focused ultrasound transducers 30 may be implemented as a conventional focused ultrasound transducer that generates focused ultrasound.
도 4는 본 발명의 실시예에 따른 집속 초음파 생성 장치를 이용한 고강도 집속 초음파 생성을 시뮬레이션한 결과이다. 도 4에서 보는 바와 같이, 2개의 집속 초음파 변환기를 이용하여 집속 초음파를 생성하는 경우, 동일한 지점에 2개의 집속 초음파 변환기의 초점(F)을 일치시켜 집속 초음파를 발생시키더라도 단일 집속 초음파 변환기를 이용하여 고강도 집속 초음파를 생성시키는 것과 동일한 효과가 발생한다. 이것은 본 발명의 실시예에서와 같이 진단용 초음파 영상을 획득하기 위해 집속 초음파 변환기를 이격시켜야 하는 경우 등의 다양한 요인에 의해 단일 집속 초음파 변환기를 사용하기 어려운 환경에서 효과적으로 고강도 집속 초음파를 생성시킬 수 있다.4 is a simulation result of the generation of high intensity focused ultrasound using the focused ultrasound generation apparatus according to the embodiment of the present invention. As shown in FIG. 4, when focusing ultrasounds are generated by using two focused ultrasound transducers, a single focused ultrasound transducer is used even if the focused ultrasounds of two focused ultrasound transducers are generated at the same point to generate focused ultrasounds. The same effect occurs as to generate high intensity focused ultrasound. This can effectively generate high intensity focused ultrasound in an environment in which it is difficult to use a single focused ultrasound transducer due to various factors, such as when the focused ultrasound transducers are spaced apart to obtain a diagnostic ultrasound image, as in the exemplary embodiment of the present invention.
이때, 복수의 집속 초음파 변환기(30)는 하우징(40)의 내부에 고정되는 지지대(10)에 설치될 수 있다. 지지대(10)의 선단에는 개구(11)가 형성되며, 이 개구(11) 둘레를 따라 복수의 초음파 변환기(30)가 배치될 수 있다.In this case, the plurality of focused ultrasound transducers 30 may be installed on the support 10 fixed inside the housing 40. An opening 11 is formed at the tip of the support 10, and a plurality of ultrasonic transducers 30 may be disposed around the opening 11.
한편, 도 1에 도시된 바와 같이, 진단용 초음파 변환기(20)는 초음파 변환기(30)의 후방에 배치될 수 있으며, 이때 진단용 초음파 변환기(20)에 의해 생성된 진단용 초음파는 지지대(10)의 개구(11)를 통과하여 전방으로 진행하게 된다.On the other hand, as shown in Figure 1, the diagnostic ultrasound transducer 20 may be disposed behind the ultrasound transducer 30, wherein the diagnostic ultrasound generated by the diagnostic ultrasound transducer 20 is the opening of the support 10 It passes through (11) and advances forward.
진단용 초음파 변환기(20)는 하우징(40)에 탈착 가능한 상태로 설치된다. 예를 들어, 진단용 초음파 변환기(20)는 하우징(40)의 중심부를 통과하는 방식으로 설치될 수 있다. 즉, 도 4를 참조하면, 하우징(40)에 횡 방향으로 관통공(43)이 형성되고, 진단용 초음파 변환기(20)가 관통공(43)에 삽입되어 설치될 수 있다. 이때 진단용 초음파 변환기(20)는 관통공(43)을 통해서 다시 배출될 수 있도록 형성됨으로써 탈착 가능하게 케이스(40)에 설치될 수 있다. 이때, 지지대(10)에도 진단용 초음파 변환기(20)가 삽입되는 관통공(13)(도 1에 도시됨)이 형성된다. 진단용 초음파 변환기(20)가 하우징(40)의 관통공(43) 및 지지대(10)의 관통공(13)에 탈착 가능한 상태로 삽입되어 설치된다.The diagnostic ultrasound transducer 20 is installed in a detachable state in the housing 40. For example, the diagnostic ultrasound transducer 20 may be installed in a manner passing through the center of the housing 40. That is, referring to FIG. 4, the through hole 43 may be formed in the housing 40 in the lateral direction, and the diagnostic ultrasound transducer 20 may be inserted into the through hole 43. In this case, the diagnostic ultrasonic transducer 20 may be formed to be discharged again through the through hole 43, and thus may be detachably installed in the case 40. At this time, the support 10 is also formed with a through hole 13 (shown in FIG. 1) through which the diagnostic ultrasonic transducer 20 is inserted. The diagnostic ultrasound transducer 20 is inserted into the through hole 43 of the housing 40 and the through hole 13 of the support 10 in a detachable state.
이와 같이 집속 초음파 변환기(30)가 하우징(40)에 탈착 가능한 상태로 설치되기 때문에, 진단용 초음파를 생성하는 진단용 초음파 변환기(20)에 비해 상대적으로 수명이 짧은 집속 초음파 변환기(30)가 수명이 다한 경우에 진단용 초음파 변환기(20)를 분리하여 재사용하고 집속 초음파 변환기(30)와 하우징(40)을 교체함으로써 진단용 초음파 변환기(20)를 재사용하여 새로운 집속 초음파 생성 장치를 구현할 수 있으며, 이에 따라 경제성이 크게 향상될 수 있다.Since the focused ultrasound transducer 30 is installed in the housing 40 in a detachable state, the focused ultrasound transducer 30, which has a relatively short lifespan, is shorter than the diagnostic ultrasound transducer 20 that generates diagnostic ultrasound. In this case, by separating and reusing the diagnostic ultrasound transducer 20 and replacing the focused ultrasound transducer 30 and the housing 40, the diagnostic ultrasound transducer 20 may be reused to implement a new focused ultrasound generating device. Can be greatly improved.
집속 초음파 변환기(30)가 설치되어 있는 지지대(10), 그리고 진단용 초음파 변환기(20)는 하우징(40)의 내부에서 이동 가능하게 설치될 수 있다. 이에 따라 치료 및 진단 부위를 이동하면서 시술할 수 있게 된다.The support 10 on which the focused ultrasound transducer 30 is installed, and the diagnostic ultrasound transducer 20 may be installed to be movable in the housing 40. Accordingly, the procedure can be performed while moving the treatment and diagnosis site.
한편, 도 1에는 집속 초음파 변환기(30)가 두 개인 경우가 도시되어 있으나, 집속 초음파 변환기(30)는 세 개 이상으로 구비될 수도 있다.On the other hand, in Figure 1 is shown a case of two focused ultrasound transducer 30, the focused ultrasound transducer 30 may be provided with three or more.
이때, 도면에 도시된 바와 같이, 복수의 집속 초음파 변환기(30)는 진단용 초음파 변환기(20)에서 생성되어 전방으로 진행하는 초음파가 통과하는 영역(A)을 형성하도록 서로 이격된 상태로 배치되도록 진단용 초음파 변환기(20)의 전방에 배치될 수 있다. 또한, 복수의 집속 초음파 변환기(30)는 방사상으로 등간격으로 배치될 수 있다. 예를 들어, 도 1 및 도 2를 참조하면, 두 개의 집속 초음파 변환기(30)가 구비되는 경우 두 개의 집속 초음파 변환기는 서로 일정 거리만큼 이격된 상태로 180도 간격으로 배치될 수 있다.In this case, as shown in the drawing, the plurality of focused ultrasound transducers 30 are diagnosed so as to be spaced apart from each other so as to form an area A through which ultrasonic waves generated by the diagnostic ultrasound transducer 20 pass forward. It may be disposed in front of the ultrasonic transducer 20. In addition, the plurality of focused ultrasound transducers 30 may be arranged radially at equal intervals. For example, referring to FIGS. 1 and 2, when the two focused ultrasound transducers 30 are provided, the two focused ultrasound transducers may be disposed at intervals of 180 degrees while being spaced apart from each other by a predetermined distance.
한편, 도 3을 참조하면, 본 발명의 다른 실시예에 따르면 네 개의 집속 초음파 변환기(30)가 구비될 수 있으며, 세 개의 집속 초음파 변환기(30)는 서로 일정 거리만큼 이격된 상태로 90도 간격으로 배치될 수 있다. 이때 네 개의 집속 초음파 변환기(30)는 공통된 하나의 초점에 집속 초음파가 집속되도록 배치될 수 있다. 그리고 집속 초음파 변환기(30)의 개수는 두 개나 네 개에 한정되지 않으며 세 개 또는 다섯 개 이상으로 구비될 수도 있다.Meanwhile, referring to FIG. 3, according to another embodiment of the present invention, four focused ultrasound transducers 30 may be provided, and the three focused ultrasound transducers 30 are spaced 90 degrees apart from each other by a predetermined distance. It can be arranged as. In this case, the four focused ultrasound transducers 30 may be arranged to focus the focused ultrasound at a common focal point. The number of focused ultrasound transducers 30 is not limited to two or four but may be provided as three or five or more.
이때, 도 1에 도시된 바와 같이, 복수의 집속 초음파 변환기(30)는 각각에 의해 생성된 집속 초음파가 공통된 초점(F)을 가지도록 배열될 수 있다. 복수의 집속 초음파 변환기(30)에서 생성된 집속 초음파가 동일한 지점에 집속되어 열을 발생하게 되고 이를 치료에 활용할 수 있게 된다. 이때, 집속 초음파 변환기(30)에 의해 생성된 집속 초음파의 초점(F)은 치료 윈도우(41)의 외부에 위치하도록 할 수 있다.In this case, as shown in FIG. 1, the plurality of focused ultrasound transducers 30 may be arranged such that the focused ultrasounds generated by each have a common focal point F. FIG. The focused ultrasounds generated by the plurality of focused ultrasound transducers 30 are focused at the same point to generate heat, which can be used for treatment. In this case, the focal point F of the focused ultrasound generated by the focused ultrasound transducer 30 may be positioned outside the treatment window 41.
한편, 도면에 도시된 바와 같이, 진단용 초음파 변환기(20)에서 생성된 초음파는 하우징(40)의 선단을 통해서 집속 초음파와 동일한 방향으로 신체에 조사된다. 이때 진단 초음파는 집속 초음파의 치료 위치와 일치하도록 형성될 수 있다. 이에 따라 집속 초음파를 이용하여 치료를 하는 동안 치료 부위를 진단용 초음파를 이용하여 실시간으로 살펴 볼 수 있다.On the other hand, as shown in the figure, the ultrasound generated by the diagnostic ultrasound transducer 20 is irradiated to the body in the same direction as the focused ultrasound through the front end of the housing 40. In this case, the diagnostic ultrasound may be formed to coincide with the treatment position of the focused ultrasound. Accordingly, during the treatment using the focused ultrasound, the treatment site may be examined in real time using the diagnostic ultrasound.
한편, 본 발명의 실시예에 따르면 진단용 초음파 변환기(20)는 2D 초음파 변환기일 수 있다. 진단용 초음파 변환기(20)가 2D 초음파 변환기인 경우 실시간으로 진단용 영상을 획득하여 진단 및 치료 효율이 향상될 수 있으며, 상대적으로 비싼 2D 초음파 변환기가 사용되더라도 복수의 집속 초음파 변환기(30)가 포함된 하우징(10)이 별도로 탈착 가능하기 때문에 진단용 초음파 변환기(20)는 분리 후 재상하고 집속 초음파 변환기(30)만을 따라 교체할 수 있어 2D 초음파 변환기가 집속 초음파 변환기(30)와 함께 폐기되는 것을 방지할 수 있어 경제성도 담보할 수 있다.Meanwhile, according to an exemplary embodiment of the present invention, the diagnostic ultrasound transducer 20 may be a 2D ultrasound transducer. If the diagnostic ultrasound transducer 20 is a 2D ultrasound transducer, diagnostic images may be obtained in real time by improving diagnostic efficiency, and a housing including a plurality of focused ultrasound transducers 30 may be used even if a relatively expensive 2D ultrasound transducer is used. Since the 10 can be detachably detached, the diagnostic ultrasound transducer 20 can be recovered after separation and replaced along only the focused ultrasound transducer 30, thereby preventing the 2D ultrasound transducer from being disposed together with the focused ultrasound transducer 30. Therefore, economic feasibility can be secured.
위에서 하우징(40)의 내부는 물이나 초음파 전달 매질로 채워지는 공간이 설치될 수 있다. 집속 초음파 변환기(30)가 물이나 초음파 전달 매질에 잠겨 있는 경우, 채워지는 물 또는 초음파 전달 매질의 초음파 감쇄 및 전달 특성을 향상시키기 위해 물 속의 기포를 제거하는 탈포화 과정을 거칠 수도 있다. 하우징(40)의 내부는 물 또는 초음파 전달 매질로 채워지기 위해 밀폐될 수 있으며, 또한 하우징(40)의 선단 및 진단용 초음파 변환기(20)와 밀착되는 면은 초음파의 감쇄가 적은 재질로 형성될 수 있다.From above, the interior of the housing 40 may have a space filled with water or an ultrasonic delivery medium. When the focused ultrasound transducer 30 is immersed in water or an ultrasonic delivery medium, desaturation may be performed to remove bubbles in the water to improve ultrasonic attenuation and delivery characteristics of the filled water or the ultrasonic delivery medium. The interior of the housing 40 may be sealed to be filled with water or an ultrasonic delivery medium, and the front end of the housing 40 and the surface in close contact with the diagnostic ultrasonic transducer 20 may be formed of a material having less attenuation of ultrasonic waves. have.
한편, 도 5를 참조하면, 본 발명의 실시예에 따른 집속 초음파 생성 장치는 진단용 초음파를 생성하는 진단용 초음파 변환기(20)를 제어하는 제1 제어 유닛(51), 집속 초음파 변환기(30)를 제어하는 제2 제어 유닛(53), 그리고 제1 제어 유닛(51)과 제2 제어 유닛(53)을 전체적으로 제어하는 시스템 제어 유닛(55)을 포함할 수 있다. 그리고 제1 제어 유닛(51)에는 진단용 초음파 변환기(20)에 의해 획득된 영상을 표시하는 모니터(57)가 연결될 수 있다.Meanwhile, referring to FIG. 5, the focused ultrasound generating apparatus according to an embodiment of the present invention controls the first control unit 51 and the focused ultrasound transducer 30 that control the diagnostic ultrasound transducer 20 that generates the diagnostic ultrasound. The second control unit 53 and the system control unit 55 for controlling the first control unit 51 and the second control unit 53 as a whole. In addition, a monitor 57 displaying an image acquired by the diagnostic ultrasound transducer 20 may be connected to the first control unit 51.
제어 유닛(51, 53, 55)들은 마이크로프로세서, 메모리, 및 관련 하드웨어와 소프트웨어를 포함하고, 미리 정해진 로직에 따른 제어 알고리즘을 수행하도록 형성될 수 있다.The control units 51, 53, 55 include a microprocessor, memory, and associated hardware and software, and may be configured to perform a control algorithm in accordance with predetermined logic.
이상에서 본 발명의 실시예를 설명하였으나, 본 발명의 권리범위는 이에 한정되지 아니하며 본 발명의 실시예로부터 본 발명이 속하는 기술분야에서 통상의 지식을 가진 자에 의해 용이하게 변경되어 균등한 것으로 인정되는 범위의 모든 변경 및 수정을 포함한다.Although the embodiments of the present invention have been described above, the scope of the present invention is not limited thereto, and the present invention is easily changed and equivalent to those of ordinary skill in the art to which the present invention pertains. Includes all changes and modifications to the scope of the matter.
본 발명은 집속 초음파 생성 장치에 관한 것으로 의료 기기 등에 적용될 수 있어 산업상 이용가능성이 있다.The present invention relates to a focused ultrasound generating device can be applied to medical devices and the like, there is industrial applicability.

Claims (6)

  1. 하우징(housing),Housing,
    상기 하우징에 설치되며 진단용 초음파를 생성하는 진단용 초음파 변환기, 그리고A diagnostic ultrasound transducer installed in the housing and generating diagnostic ultrasound;
    상기 하우징에 설치되어 집속 초음파(high intensity focused ultrasound, HIFU)를 생성하는 복수의 집속 초음파 변환기를 포함하는 진단 기능을 구비하는 집속 초음파 생성 장치.And a plurality of focused ultrasound transducers installed in the housing to generate focused ultrasound (HIFU).
  2. 제1항에서,In claim 1,
    상기 진단용 초음파 변환기는 상기 하우징에 탈착 가능한 상태로 설치되는 진단 기능을 구비하는 집속 초음파 생성 장치.The diagnostic ultrasound transducer is a focused ultrasound generating device having a diagnostic function that is installed in a removable state in the housing.
  3. 제1항에서,In claim 1,
    상기 진단용 초음파 변환기는 2D 초음파 변환기인 진단 기능을 구비하는 집속 초음파 생성 장치.The diagnostic ultrasound transducer is a focused ultrasound generating device having a diagnostic function that is a 2D ultrasound transducer.
  4. 제1항에서,In claim 1,
    상기 복수의 집속 초음파 변환기는 상기 진단용 초음파 변환기에서 생성되어 전방으로 진행하는 초음파가 통과하는 영역을 형성하도록 서로 이격된 상태로 배치되도록 상기 진단용 초음파 변환기의 전방에 설치되는 진단 기능을 구비하는 집속 초음파 생성 장치.The plurality of focused ultrasound transducers may include a focused ultrasound generator having a diagnostic function installed in front of the diagnostic ultrasound transducer so that the plurality of focused ultrasound transducers are spaced apart from each other so as to form an area through which the ultrasound waves generated by the diagnostic ultrasound transducer pass forward. Device.
  5. 제4항에서,In claim 4,
    상기 복수의 집속 초음파 변환기는 방사상으로 등간격으로 배치되는 진단 기능을 구비하는 집속 초음파 생성 장치.And a plurality of focused ultrasound transducers having diagnostic functions arranged radially at equal intervals.
  6. 제4항에서,In claim 4,
    복수의 집속 초음파 변환기는 생성된 집속 초음파가 공통된 초점을 가지도록 배열되는 집속 초음파 생성 장치.The plurality of focused ultrasound transducers are arranged so that the generated focused ultrasound has a common focus.
PCT/KR2011/005552 2010-07-30 2011-07-28 Apparatus for generating high intensity focused ultrasound WO2012015248A2 (en)

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