WO2012054413A4 - Space-filling intragastric implants with fluid flow - Google Patents
Space-filling intragastric implants with fluid flow Download PDFInfo
- Publication number
- WO2012054413A4 WO2012054413A4 PCT/US2011/056608 US2011056608W WO2012054413A4 WO 2012054413 A4 WO2012054413 A4 WO 2012054413A4 US 2011056608 W US2011056608 W US 2011056608W WO 2012054413 A4 WO2012054413 A4 WO 2012054413A4
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- implant
- devices
- stomach
- chambers
- flow channel
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices; Anti-rape devices
- A61F5/0003—Apparatus for the treatment of obesity; Anti-eating devices
- A61F5/0013—Implantable devices or invasive measures
- A61F5/003—Implantable devices or invasive measures inflatable
- A61F5/0033—Implantable devices or invasive measures inflatable with more than one chamber
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices; Anti-rape devices
- A61F5/0003—Apparatus for the treatment of obesity; Anti-eating devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices; Anti-rape devices
- A61F5/0003—Apparatus for the treatment of obesity; Anti-eating devices
- A61F5/0013—Implantable devices or invasive measures
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices; Anti-rape devices
- A61F5/0003—Apparatus for the treatment of obesity; Anti-eating devices
- A61F5/0013—Implantable devices or invasive measures
- A61F5/003—Implantable devices or invasive measures inflatable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices; Anti-rape devices
- A61F5/0003—Apparatus for the treatment of obesity; Anti-eating devices
- A61F5/0013—Implantable devices or invasive measures
- A61F5/0036—Intragastrical devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices; Anti-rape devices
- A61F5/0003—Apparatus for the treatment of obesity; Anti-eating devices
- A61F5/0013—Implantable devices or invasive measures
- A61F5/0083—Reducing the size of the stomach, e.g. gastroplasty
- A61F5/0086—Reducing the size of the stomach, e.g. gastroplasty using clamps, folding means or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices; Anti-rape devices
- A61F5/0003—Apparatus for the treatment of obesity; Anti-eating devices
- A61F5/0013—Implantable devices or invasive measures
- A61F5/0076—Implantable devices or invasive measures preventing normal digestion, e.g. Bariatric or gastric sleeves
- A61F5/0079—Pyloric or esophageal obstructions
Abstract
A variety of passive intragastric implant devices for obesity treatment are disclosed. Such passive devices do not autonomously change shape, but instead react within the stomach to induce satiety. The devices may take up volume within the stomach, thus reducing the intake capacity. Additionally, the devices may contact areas within the stomach, such as the cardia surrounding the esophageal sphincter, to stimulate satiety-inducing nerves. Also, certain devices slow gastric emptying by blocking or otherwise impeding flow through the pyloric sphincter. A number of devices combine two or more of these satiety-inducing features. Methods of implant are disclosed including compressing the devices within a delivery tube and transorally advancing the devices through the esophagus to be deployed within the stomach. Removal of the devices occurs in the reverse.
Claims
1. A passive intragastric obesity treatment implant, comprising:
an inflatable body having a length along a longitudinal direction sufficient to extend between the cardia at a superior end and the pyloric sphincter at an inferior end upon implant in the stomach, and a width in a circumferential direction sufficient to contact the interior stomach walls upon contraction thereof, the body being rounded and slightly tapered from the superior end to the inferior end so as to generally conform to the volume of an adult stomach cavity, the body including a series of chambers spaced apart in the longitudinal direction and fluidly connected so as to be capable of simultaneous inflation and deflation, wherein two chambers at the superior end are separated in the longitudinal direction by an annular recess arranged circumferentially that is positioned to open to the esophageal sphincter, and wherein apertures in the annular recess open to a central flow channel that extends from the annular recess to the inferior end of the body, and some of the chambers surround the central flow channel,
the implant being formed of a material which permits it to be compressed into a substantially linear delivery configuration and that will resist degradation over a period of at least six months within the stomach.
2. The implant of claim 1, wherein the central flow channel has a star-shaped cross- section.
3. The implant of claim 1, further including a plurality of circumferential grooves extending around the body and between adjacent chambers, and radial passages connecting the circumferential grooves to the central flow channel.
4. The implant of claim 1, wherein the chambers gradually decrease in diameter from the superior to the inferior ends of the body.
5. The implant of claim 1, wherein the body includes a rounded superior end that mimics the shape of the surrounding cardia and defines a proximal chamber therein.
30
6. The implant of claim 1, wherein the body defines a proximal chamber at the superior end and three annular chambers spaced apart in the longitudinal direction toward the inferior end.
7. The implant of claim 6, wherein the three annular chambers gradually decrease in diameter in the longitudinal direction toward the inferior end.
8. The implant of claim 1, wherein the inferior end of the central flow channel is scallop-shaped.
9. A system for deploying an obesity treatment implant into the stomach, comprising:
the passive intragastric obesity treatment implant of claim 1, the implant having a fill valve;
a thin-walled tube into which the deflated implant is compressed; an elongated obturator for pushing the implant; and
a fill tube connected to the implant fill valve.
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13/275,211 US9095405B2 (en) | 2010-10-19 | 2011-10-17 | Space-filling intragastric implants with fluid flow |
ES11773973.0T ES2594484T3 (en) | 2010-10-19 | 2011-10-18 | Intragastric space filling implants with fluid flow |
EP11773973.0A EP2629712B1 (en) | 2010-10-19 | 2011-10-18 | Space-filling intragastric implants with fluid flow |
PCT/US2011/056608 WO2012054413A2 (en) | 2010-10-19 | 2011-10-18 | Space-filling intragastric implants with fluid flow |
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US39459210P | 2010-10-19 | 2010-10-19 | |
US61/394,592 | 2010-10-19 | ||
US201161485009P | 2011-05-11 | 2011-05-11 | |
US61/485,009 | 2011-05-11 | ||
PCT/US2011/056608 WO2012054413A2 (en) | 2010-10-19 | 2011-10-18 | Space-filling intragastric implants with fluid flow |
Publications (3)
Publication Number | Publication Date |
---|---|
WO2012054413A2 WO2012054413A2 (en) | 2012-04-26 |
WO2012054413A3 WO2012054413A3 (en) | 2012-06-21 |
WO2012054413A4 true WO2012054413A4 (en) | 2012-08-09 |
Family
ID=46025986
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2011/056608 WO2012054413A2 (en) | 2010-10-19 | 2011-10-18 | Space-filling intragastric implants with fluid flow |
Country Status (4)
Country | Link |
---|---|
US (1) | US9095405B2 (en) |
EP (1) | EP2629712B1 (en) |
ES (1) | ES2594484T3 (en) |
WO (1) | WO2012054413A2 (en) |
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2011
- 2011-10-17 US US13/275,211 patent/US9095405B2/en active Active
- 2011-10-18 EP EP11773973.0A patent/EP2629712B1/en not_active Not-in-force
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- 2011-10-18 ES ES11773973.0T patent/ES2594484T3/en active Active
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EP2629712B1 (en) | 2016-07-20 |
US20120095495A1 (en) | 2012-04-19 |
US9095405B2 (en) | 2015-08-04 |
WO2012054413A3 (en) | 2012-06-21 |
ES2594484T3 (en) | 2016-12-20 |
WO2012054413A2 (en) | 2012-04-26 |
EP2629712A2 (en) | 2013-08-28 |
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