WO2014015691A1

WO2014015691A1 - Blood gas analyzer and method of use thereof

Info

Publication number: WO2014015691A1
Application number: PCT/CN2013/074830
Authority: WO
Inventors: 侯兴凯; 姚新宁
Original assignee: 深圳市麦迪聪医疗电子有限公司; 梅州康立高科技有限公司
Priority date: 2012-07-20
Filing date: 2013-04-26
Publication date: 2014-01-30
Also published as: CN102735829B; CN102735829A

Abstract

Disclosed is a blood gas analyzer, comprising a needle valve (101) situated in a sampling frame, a sample box (2) connected to the needle valve, a first pump body (4) connected to the sample box, a waste liquid bag (7) connected to the first pump body, a liquid detector (18) connected to the needle valve and a second pump body (5), a third electromagnetic valve (11) connected to the liquid detector, a first electromagnetic valve (8) connected to the second pump body, and a third pump body (6) connected to the needle valve and the waste liquid bag, wherein in the sample box, one end of a front detector (201) is connected to the needle valve and the other end is successively connected to a detection membrane tube (202) and a rear detector (203), and the rear detector is connected to the first pump body; the preceding components are connected to each other through flow tubes (3); a memory device (205) is connected to the detection membrane tube via electrodes (204); and both the first electromagnetic valve (8) and a second electromagnetic valve (9) are provided with air inlets. By means of the calibration of a liquid instead of the prior art method of mixed calibration of a gas and liquid, faults caused by the liquid entering an air path can be avoided, and the reliability of the instrument is improved.

Description

Blood gas analyzer and method of using same

[0001] The present invention relates to the field of medical testing, and in particular, to a blood gas analyzer and a method of using the same.

Background technique

[0002] The PC02 and P02 electrodes of the domestic domestic blood gas analyzer are calibrated by using two kinds of compressed gas with different gas ratios, such as high gas and low gas, after decompression, heat preservation and humidification, and then introduced into the electrode measurement channel for calibration. The electrodes are calibrated using standard liquids. In this calibration method, the flow path is divided into the gas path and the liquid path, and the control of the gas-liquid intersection is complicated. Especially in the case of a failure, the calibration liquid or the cleaning liquid enters the gas path and easily damages the electromagnetic valve. Due to the presence of gas cylinders, the instrument is inconvenient to be portable or hand-pushable for mobile use, making standard gas transport inconvenient; since the standard gas is compressed gas, the gas cylinder is large, inconvenient to transport and use, compressed gas It is only available after decompression, heat preservation and humidification, and the use process is cumbersome. Therefore, there is an urgent need for a blood and blood analyzer that is convenient to use and reliable in quality.

Summary of the invention

[0003] The object of the present invention is to provide a blood gas analyzer and a method for using the same, which replaces the prior art gas and liquid mixing calibration method by liquid calibration, which is more convenient to use and avoids the entry of liquid into the gas path. The failure of the fault reduces the probability of failure, thereby improving the reliability of the instrument.

[0004] The technical solution of the present invention is: a blood gas analyzer, comprising: a needle valve placed in a sampling rack, a sample box connecting the needle valve, a first pump body connecting the sample box, and connecting the a waste bag of the first pump body, a liquid detector connecting the needle valve and the second pump body, a fourth reagent bag connected to the second pump body through the second electromagnetic valve, and a liquid detector connected to the liquid detector a third solenoid valve, a first solenoid valve connected to the second pump body, a first reagent bag connected to the liquid detector through a sixth solenoid valve, and a second reagent port connected to the liquid detector through a fifth solenoid valve a reagent bag, a third reagent bag connected to the liquid detector through a fourth electromagnetic valve, and a second pump body connecting the needle valve and the waste liquid bag; in the sample box, one end of the front detector is connected to the needle valve, and the other end is in turn Connecting the detecting film tube and the rear detector, the rear detector is connected to the first pump body; the foregoing components are connected by a flow pipe; the memory is connected to the film tube through the electrode connection; each of the above reagent bags is filled with a different liquid, Electromagnetic And the third electromagnetic valve has an air inlet. When the liquid detector detects the liquid, the electromagnetic valve for opening the liquid that has been opened is closed, the third electromagnetic valve is opened, the air replaces the liquid and enters the flow tube, and the balanced flow path is The air pressure in the inner and outer spaces allows the liquid in the flow tube to smoothly enter the detection membrane tube and save the liquid; when the second electromagnetic valve opens to extract the cleaning liquid, the first electromagnetic valve is opened, and the air can enter the flow tube The air and the cleaning liquid are mixed, and a segmented cleaning liquid is formed in the flow pipe, and the cleaning is more thorough.

[0005] wherein the third electromagnetic valve, the fourth electromagnetic valve, the fifth electromagnetic valve, and the sixth electromagnetic valve are arranged side by side, in order The flow path tube between the second pump body and the liquid detector is connected, and the third electromagnetic valve is closest to the second pump body. The electromagnetic valve reacts quickly, the switch is flexible, and the automatic control makes the blood gas analyzer easy to use. The first reagent bag has a first reagent, and the second reagent bag has a second reagent. Among the first reagent and the second reagent, the value of the target to be tested is determined before the detection, is known, and will be detected twice. The value is compared with the two determined values. If the detected value is the same as the determined value, the blood gas analyzer is accurate and can be used continuously. If the detected value and the determined value are different, the blood gas analyzer is inaccurate. , need to adjust the blood gas analyzer. In the memory in which the first reagent, the second reagent, and the sample-detected data are stored, the user performs judgment and analysis based on the data obtained by detecting the sample, and performs subsequent operations. In the technical solution, only the liquid is used, no gas is used, so the gas cylinder is not used, which facilitates the transportation and movement of the instrument; the use of the liquid is simple, and the use of the gas is required to reduce the pressure, heat preservation and humidification. Trouble; Avoid failures caused by liquid entering the gas path, reducing the chance of failure, thereby improving the reliability of the instrument.

[0006] Further, the needle valve has a main channel, and the main channel has a first sampling port and a second sampling port, the first sampling port is connected to the first channel, and the second sampling port is connected to the second channel. The first reagent, the second reagent, the deproteinizing liquid, and the cleaning liquid enter the main channel in the needle valve through the first passage, enter the subsequent flow path tube at the first sampling port of the main channel; and enter the main channel when cleaning the flow path; The cleaning liquid is divided into two parts, one part enters the flow path tube from the first sampling port, cleans the sample box and the subsequent flow path, and finally enters the waste liquid bag, and the other part enters the second channel from the second sampling port, and the third pump The body is pumped out, and finally enters the waste bag. The setting of each channel in the needle valve satisfies the requirements of blood gas analyzer calibration, deproteinization, sampling and cleaning flow path, and is convenient to use, and avoids failure caused by liquid entering the gas path. Reduces the chance of failure and improves instrument reliability.

[0007] Further, the first channel is connected to the liquid detector, so that the first reagent, the second reagent, the deproteinized liquid, and the cleaning liquid enter the main channel in the needle valve through the flow tube, and the second channel passes through the flow. The road pipe is connected to the third pump body, so that the cleaning liquid can smoothly pass through the third pump body and enter the waste liquid bag, thereby facilitating the cleaning of the flow path.

[0008] Further, the blood gas analyzer further includes a sample collector, the sample collector is inserted into the second sampling port, and the sampling needle is inserted into the sample collector through the main channel, and the sample in the sample collector is extracted, and after the extraction is completed, The sampling needle is pulled out, and the sample collector is also pulled out from the second sampling port, which is convenient to use.

[0009] Further, one end of the sampling needle is inserted into the sample collector through the main channel, and the other end is connected to the front detector. The front end of the sampling needle has a pinhole. Under the action of the first pump body, the needle of the test sample needle passes through the side wall. The hole extracts the sample in the sample collector, and the sample enters the test film tube through the front detector, which is convenient for detection and convenient to use.

[0010] The present invention also provides a method for using a blood gas analyzer, comprising the following steps:

S1, determining a first standard value: opening the sixth electromagnetic valve, the first pump body extracts the first reagent in the first reagent bag through the flow path tube; when the liquid detector detects the first reagent, closes the sixth electromagnetic valve, opens The third solenoid valve, the first reagent enters the detection membrane tube When the first detector detects the first reagent, the first pump body stops rotating, closes the third solenoid valve, the electrode starts the test, and saves the test data in the memory as the first standard value; then opens the third a solenoid valve, the first pump body draws the first reagent in the flow path into the waste bag;

S2, determining a second standard value: opening the fifth electromagnetic valve, the first pump body extracts the second reagent in the second reagent bag through the flow path tube; when the liquid detector detects the second reagent, closes the fifth electromagnetic valve, opens a third solenoid valve, the second reagent enters the detection membrane tube; when the second detector detects the second reagent, the first pump body stops rotating, the electrode starts testing, and the test data is stored in the memory as a second standard Value; then opening the third solenoid valve, the first pump body draws the second reagent in the flow path into the waste bag;

S3, deproteinizing: opening the fourth electromagnetic valve, the first pump body extracts the deproteinizing liquid in the third reagent bag through the flow path tube; when the liquid detector detects the deproteinizing liquid, the first pump body continues to rotate counterclockwise Then, the fourth electromagnetic valve is closed, the third electromagnetic valve is opened, and the deproteinized liquid enters the detection membrane tube; when the deproteinized liquid is detected by the rear detector, the first pump body continues to rotate, and when the deproteinized liquid begins to enter the waste liquid bag When the third solenoid valve is closed, the deproteinized solution is sufficiently reacted with the blood protein remaining in the flow path. Finally, the first pump body rotates, and the deproteinized waste liquid in the flow pipe is pumped into the waste bag;

S4, sampling: the sampling needle is inserted into the sample, the first pump body rotates counterclockwise, and the sample is taken; then the sampling needle is taken out from the sample, and the first pump body draws the sample in the flow path through the front detector into the detecting membrane tube, The sample is continuously detected by the detector before passing the sample. When the sample passes through the front detector, the first pump body stops rotating, the electrode detects the sample, and the detection result is stored in the memory, and the first pump rotates, and the flow is in the flow path. The sample is discharged into the waste bag;

S5, cleaning flow path: the first electromagnetic valve intermittent switch, opening the second electromagnetic valve, the second pump body pumping the cleaning liquid in the fourth reagent bag to the main channel in the needle valve through the flow path tube; For the normally open, the second solenoid valve is closed, and the first pump body pushes the second pump body into a part of the main passage, and the cleaning liquid is sequentially pumped through the first sampling port and the sample box to the waste bag; and the third pump body is second. The pump body is pushed into the main passage of the needle valve and another part of the cleaning liquid overflowing to the second sampling port is pumped to the waste liquid bag; the second pump body continuously rotates until the liquid detector detects the cleaning liquid, the first pump After the body and the third pump body pump all the cleaning liquid in the flow path to the waste liquid bag, the rotation is stopped.

[0011] wherein, the first reagent bag is filled with the first reagent, the second reagent bag is filled with the second reagent, the third reagent bag is filled with the deproteinized liquid, and the fourth reagent bag is filled with the cleaning liquid; a solenoid valve, a fourth solenoid valve, a fifth solenoid valve and a sixth solenoid valve are arranged side by side, and sequentially connect the flow path tube between the second pump body and the liquid detector in order, the third electromagnetic valve being closest to the first The two pump body, the solenoid valve reacts quickly, the switch is flexible, and the automatic control makes the blood gas analyzer easy to use. In the first reagent and the second reagent, the value of the target to be measured is determined before the detection, and is known, and the values of the two detections are respectively compared with the two determined values, if the detected value and the determined value are the same It means that the blood gas analyzer is accurate and can continue to be used. If the detected value and the determined value are different, the blood gas analyzer is inaccurate and the blood gas analysis needs to be adjusted. Instrument. In the memory in which the first reagent, the second reagent, and the sample-detected data are stored, the user performs judgment and analysis based on the data obtained by detecting the sample, and performs subsequent operations. In the technical solution, only the liquid is used, no gas is used, so the gas cylinder is not needed, and the transportation and movement of the instrument are facilitated; the use of the liquid is simple, and the use of the gas is required to reduce the pressure, heat preservation and humidification. Trouble; avoid failures caused by liquid entering the gas path, reducing the chance of failure, thereby improving the reliability of the instrument.

[0012] Further, in the step S1, the pinhole of the sampling needle is located at the first sampling port, the first reagent flows through the first channel, and enters the sampling needle from the pinhole; in the step S2, the needle of the sampling needle The hole is located at the first sampling port, and the second reagent flows through the first channel and enters the sampling needle from the pinhole. In steps S1 and S2, the sampling needle is located at the first sampling port, so that the liquid entering the first sampling port can enter the subsequent flow path from the sampling needle, which is convenient to use, and at the same time, only the liquid is detected, thereby avoiding the liquid entering the gas path. The failure of the fault reduces the probability of failure, thereby improving the reliability of the instrument.

[0013] Further, in step S4, the bottle mouth of the sample collector is inserted into the second sampling port, the sampling needle is inserted into the sample collector through the main channel, and the sample in the sample collector is taken through the pinhole, and after the sample is taken out, Pull out the sampling needle for subsequent operation, which is convenient to use.

[0014] Advantageous Effects of the Invention: The method for replacing the gas and liquid mixing calibration in the prior art by liquid calibration is more convenient to use, avoids the failure caused by the liquid entering the gas path, and reduces the probability of failure. Thereby improving the reliability of the instrument.

DRAWINGS

1 is a schematic structural view of an embodiment of the present invention;

Figure 2 is a longitudinal sectional view of a needle valve in an embodiment of the present invention;

Figure 3 is a longitudinal cross-sectional view of a sampling hour hand valve in one embodiment of the present invention.

[0016] In the figure, the mark is: 1-sampling frame; 101-needle valve; 102-main channel; 103-first channel; 104-second channel; 105-first sampling port; 106-second sampling port; Sampling needle; 108-pinhole; 109-sample collector; 2-sample box; 201-front detector; 202-detection membrane tube; 203-post detector; 204-electrode; 205-memory; 3-flow tube 4- first pump body; 5-second pump body; 6-third pump body; 7-waste bag; 8-first solenoid valve; 9-second solenoid valve; 10-four reagent bag; - third solenoid valve; 12 - fourth solenoid valve; 13 - third reagent bag; 14 - fifth solenoid valve; 15- second reagent bag; 16 - sixth solenoid valve; 17 - first reagent bag; Liquid detector.

detailed description

[0017] The preferred embodiments of the present invention are further described in detail below with reference to the accompanying drawings:

Embodiment 1, Referring to FIG. 1, a blood gas analyzer includes: a needle valve 101 placed in a sampling rack 1, a sample box 2 connected to the needle valve 2, and a first pump body 4 connecting the sample box 2. a waste liquid bag 7 connecting the first pump body 4, connecting the needle a valve 101 and a liquid detector 18 of the second pump body 5, a fourth reagent bag 10 connected to the second pump body 5 via a second solenoid valve 9, a third solenoid valve 11 connected to the liquid detector 18, a first solenoid valve 8 connected to the second pump body 5, a first reagent bag 17 connected to the liquid detector 18 via a sixth solenoid valve 16, and a first detector bag 17 connected to the liquid detector 18 via a fifth solenoid valve 14. a second reagent bag 15, a third reagent bag 13 connected to the liquid detector 18 through a fourth electromagnetic valve 12, and a second pump body 5 connecting the needle valve 101 and the waste liquid bag 7; in the sample box 2, pre-detection One end of the device 201 is connected to the needle valve 101, the other end is connected to the detecting membrane tube 202 and the rear detector 203 in turn, and the rear detector 203 is connected to the first pump body 4; the aforementioned components are connected by the flow path tube 3; The electrode 204 is connected to the detecting membrane tube; each of the above reagent bags is provided with a different liquid, and the first electromagnetic valve 8 and the third electromagnetic valve 11 have an air inlet, and when the liquid detector 18 detects the liquid, the liquid has been opened. The solenoid valve for pumping liquid is closed, the third solenoid valve 11 is opened, and air is replaced. The liquid enters the flow path tube 3, balances the air pressure in the flow path tube 3 and the external space, so that the liquid in the flow path tube 3 smoothly enters the detection film tube 202 for detection, and at the same time saves the liquid; when the second electromagnetic valve 9 opens to extract the cleaning liquid When the first electromagnetic valve 8 is opened, air can be introduced into the flow path tube 3, and the air and the cleaning liquid are mixed, and a segmented cleaning liquid is formed in the flow path tube 3, and the cleaning is more thorough.

[0018] wherein the third electromagnetic valve 11, the fourth electromagnetic valve 12, the fifth electromagnetic valve 14 and the sixth electromagnetic valve 16 are arranged side by side, and sequentially connect the flow path between the second pump body 5 and the liquid detector 18 in this order. The third electromagnetic valve 11 is closest to the second pump body 5. The electromagnetic valve reacts quickly, the switch is flexible, and the automatic control makes the blood gas analyzer easy to use. The first reagent bag 17 has a first reagent, and the second reagent bag 15 has a second reagent. Among the first reagent and the second reagent, the value of the target to be tested is determined before the detection, is known, and will be twice. The detected values are compared with the two determined values. If the detected value is the same as the determined value, the blood gas analyzer is accurate and can continue to be used. If the detected value and the determined value are different, the blood gas analyzer is indicated. Inaccurate, the blood gas analyzer needs to be adjusted. In the memory 205 in which the first reagent, the second reagent, and the sample-detected data are stored, the user judges and analyzes the data obtained by detecting the sample, and performs subsequent operations. In the technical solution, only the liquid is used, no gas is used, so the gas cylinder is not used, which facilitates the transportation and movement of the instrument; the use of the liquid is simple, and the use of the gas is required to reduce the pressure, heat preservation and humidification. Trouble; avoid failures caused by liquid entering the gas path, reducing the chance of failure, thereby improving the reliability of the instrument.

[0019] Embodiment 2, referring to FIG. 2, the needle valve 101 has a main channel 102. The main channel 102 has a first sampling port 105 and a second sampling port 106. The first sampling port 105 is connected to the first channel 103. The second sampling port 106 is connected to the second channel 104; the first reagent, the second reagent, the deproteinizing solution and the cleaning liquid enter the main channel 102 in the needle valve 101 through the first channel 103, and the first sampling in the main channel 102 The port 105 enters the subsequent flow path tube 3; when cleaning the flow path, the cleaning liquid entering the main channel 102 is divided into two parts, and a part enters the flow path tube 3 from the first sampling port 105, and the sample box 2 is cleaned and the subsequent flow path is cleaned. Finally, the waste liquid bag 7 is entered, and the other part enters the second passage 104 from the second sampling port 106, is withdrawn by the third pump body 6, and finally enters the waste liquid bag 7, and the setting of each channel in the needle valve 101 satisfies the blood gas analyzer Calibration, deproteinization, sampling and cleaning The need of the flow path is convenient to use, avoids the failure caused by the liquid entering the gas path, reduces the probability of failure, and improves the reliability of the instrument.

[0020] Embodiment 3, referring to FIG. 1 and FIG. 2, the first channel 103 is connected to the liquid detector 18, so that the first reagent, the second reagent, the deproteinizing liquid and the cleaning liquid enter the needle valve 101 through the flow tube 3. The main passage 102, the second passage 104 is connected to the third pump body 6 through the flow pipe 3, so that the cleaning liquid can smoothly pass through the third pump body 6 and enter the waste liquid bag 7, thereby facilitating the cleaning of the flow path.

[0021] Embodiment 4, Referring to FIG. 3, the blood gas analyzer further includes a sample collector 109, the sample collector 109 is inserted into the second sampling port 106, and the sampling needle 107 is inserted into the sample collector 109 through the main channel 102, and sample collection is performed. After the sample in the device 109 is extracted, the sampling needle 107 is pulled out, and the sample collector 109 is also pulled out from the second sampling port 106, which is convenient to use.

[0022] Embodiment 5, referring to FIG. 1 and FIG. 3, one end of the sampling needle 107 is inserted into the sample collector through the main channel 102, and the other end is connected to the front detector 201. The sampling needle 107 has a pinhole 108 at the front end thereof. Under the action of the pump body 4, the test sample needle 107 draws the sample in the sample collector through the pinhole 108 of the side wall, and the sample enters the test film tube through the front detector 201, which is convenient for detection and convenient to use.

[0023] Embodiment 6, Referring to FIG. 1 to FIG. 3, a method for using a blood gas analyzer includes the following steps:

Sl, determining the first standard value: opening the sixth solenoid valve 16, the pinhole 108 is aligned with the first sampling port 105, and the first pump body 4 is rotated counterclockwise to extract the first reagent in the first reagent bag 17. When the liquid detector 18 detects the first reagent, the sixth electromagnetic valve 16 is closed, the third electromagnetic valve 11 is opened, and the gas enters the flow path tube 3 through the air inlet on the third electromagnetic valve 11, and the first pump body 4 continues. Turning counterclockwise, when the rear detector 203 in the sample box 2 detects the first reagent, the first pump body 4 stops rotating and the third solenoid valve 11 closes. At this time, the entire flow path of the sample box 2 is filled with the first reagent, the electrode 204 starts the test, and the test data is stored in the memory as the first standard value. Then the third solenoid valve 11 is opened, and the first pump body 4 rotates counterclockwise to draw the first reagent in the flow path into the waste liquid bag 7;

S2, determining the second standard value: opening the fifth electromagnetic valve 14, the pinhole 108 is aligned with the second sampling port 106, and the first pump body 41 is rotated counterclockwise to extract the second reagent in the second reagent bag 15. When the liquid detector 18 detects the second reagent, the fifth solenoid valve 14 is closed, the third solenoid valve 11 is opened, and the gas enters the flow path tube 3 through the intake port on the third solenoid valve 11, and the first pump body 4 continues. Turning counterclockwise, when the rear detector 203 in the sample box 2 detects the second reagent, the first pump body 4 stops rotating. At this time, the entire flow path of the sample box 2 is filled with the second reagent, the electrode 204 starts the test, and the test data is stored in the memory as the second standard value. The third solenoid valve 11 is opened, the first pump body 4 is rotated counterclockwise, and the second reagent in the flow path is drawn into the waste liquid bag 7;

S3, Deproteinization: The fourth solenoid valve 12 is opened, the pinhole 108 is aligned with the first sampling port 105, and the first pump body 4 is rotated counterclockwise to extract the deproteinized liquid in the third reagent bag 13. When the liquid detector 18 detects the deproteinized liquid, the first pump body 4 continues Rotating counterclockwise, then closing the fourth solenoid valve 12, opening the third solenoid valve 11, the air inlet of the third solenoid valve 11 enters the flow tube 3, and the first pump body 4 continues to rotate counterclockwise, when the sample When the post-detector 203 in the tank 2 detects the deproteinizing liquid, the first pump body 4 continues to rotate counterclockwise, and when the deproteinized liquid enters the waste liquid bag 7, the third solenoid valve 11 is closed. At this time, the entire flow path is filled with the deproteinized solution, and the deproteinized solution stays in the flow path for 3 minutes to fully react the deproteinized liquid with the residual blood protein in the flow path. Finally, the first pump body 4 rotates counterclockwise, and the deproteinized waste liquid in the flow path tube 3 is drawn into the waste liquid bag 7;

S4, sampling: the sampling needle 107 is inserted into the sample, the first pump body 4 rotates counterclockwise to take the sample, the first pump body 4 continues to rotate counterclockwise 4 times, the sampling needle 107 is withdrawn from the sample, and the pinhole 108 is open to the atmosphere. The first pump body 4 continues to rotate counterclockwise, and the sample in the flow path is drawn into the front detector 201. The first pump body 4 continues to twitch the sample to move forward, and the front detector 201 continuously detects when the sample has been detected. After the detector 201, the first pump body 4 stops rotating, at which time the sample fills the detection membrane tube 202, the electrode 204 detects the sample, and stores the detection result in the memory 205. After the end of the test, the first pump body 4 rotates counterclockwise to discharge the sample in the flow path into the waste bag 7;

S5, cleaning flow path: opening the second electromagnetic valve 9, the sampling needle 107 of the needle valve 101 is moved to the first sampling port 105. The second pump body 5 rotates counterclockwise to extract the cleaning liquid in the fourth reagent bag 10, the first electromagnetic valve 8 intermittently switches, the gas-liquid segment is formed in the liquid pumped by the second pump, and the second pump body 5 continuously rotates, The liquid-liquid segmented liquid is pushed toward the needle valve 101 in the flow path. When the first electromagnetic valve 8 is opened and closed to produce the 9-stage gas-liquid segment, the first electromagnetic valve 8 is changed to normally open, and the second electromagnetic is turned off. The valve 9, the second pump body 5 pushes the gas-liquid mixed liquid in the flow path to the needle valve 101, and when the liquid detector 18 in the flow path detects the cleaning liquid, the first pump body 4 rotates counterclockwise to move the second pump body 5 a part of the gas-liquid segmented cleaning liquid pushed into the valve chamber is sequentially drawn to the waste liquid bag 7 through the first sampling port 105 and the sample box 2 to clean the first sampling port 105 to the sample box 2 part of the flow path; and the third pump The body 6 rotates clockwise, pushing the second pump body 5 into the main passage 102 of the needle valve 101 and overflowing the other part of the gas-liquid segmented liquid of the second sampling port 106 to the waste liquid bag 7 to clean the needle The main passage 102 of the valve 101. The second pump body 5 continuously pushes the gas-liquid segmented liquid inlet needle valve 101 until the liquid detector 18 detects the cleaning fluid, the second pump body 5 stops rotating, and the first pump body 4 and the third pump body 6 will flow. After the cleaning liquid in the road is completely drawn to the waste liquid bag 7, the rotation is stopped.

[0024] In step S4, the bottle mouth of the sample collector 109 is inserted into the second sampling port 106, the sampling needle 107 is inserted into the sample collector 109 through the main channel 102, and the sample in the sample collector 109 is taken through the pinhole 108. After the sample is taken out, the sampling needle 107 is taken out for subsequent operations, which is convenient to use.

[0025] in the first reagent and the second reagent, the value of the target to be measured is determined before the detection, and is known, and the values of the two detections are respectively compared with the two determined values, if the detected values are The same value is determined, indicating that the blood gas analyzer is accurate and can continue to be used. If the detected value and the determined value are different, the blood gas analyzer is inaccurate and the blood gas analyzer needs to be adjusted. In the memory 205 in which the first reagent, the second reagent, and the sample detected data are saved, The user performs judgment and analysis based on the data obtained by detecting the sample, and performs subsequent operations. The above embodiment replaces the prior art gas and liquid mixing calibration method by liquid calibration, which is more convenient to use, avoids the failure caused by the liquid entering the gas path, reduces the probability of failure, and improves the reliability of the instrument. .

The above is a further detailed description of the present invention in conjunction with the specific preferred embodiments. It will be apparent to those skilled in the art that the present invention may be practiced without departing from the spirit and scope of the invention.

Claims

Claim

A blood gas analyzer, comprising: a needle valve placed in a sampling rack, a sample box connecting the needle valve, a first pump body connected to the sample box, and a first pump body connected a waste liquid bag, a liquid detector connecting the needle valve and the second pump body, a fourth reagent bag connected to the second pump body through a second electromagnetic valve, and a third electromagnetic valve connected to the liquid detector a first electromagnetic valve connected to the second pump body, a first reagent bag connected to the liquid detector through a sixth electromagnetic valve, a second reagent bag connected to the liquid detector through a fifth electromagnetic valve, and passed through a fourth electromagnetic valve is connected to the third reagent bag of the liquid detector and a second pump body connecting the needle valve and the waste liquid bag; in the sample box, one end of the front detector is connected to the needle valve, and the other end is connected to the detection film tube in turn. And the rear detector, the rear detector is connected to the first pump body; the foregoing components are connected by a flow tube; the memory is connected to the membrane tube through the electrode connection; the first solenoid valve and the second solenoid valve have air inlets.

2. The blood gas analyzer according to claim 1, wherein: the needle valve has a main channel, a first channel, and a second channel, and the main channel has a first sampling port and a second sampling port, The first sampling port is connected to the first channel, and the second sampling port is connected to the second channel.

3. The blood gas analyzer according to claim 2, wherein: the first passage is connected to the liquid detector, and the second passage is connected to the third pump through the flow conduit.

4. The blood gas analyzer according to claim 3, further comprising: a sample collector, the sample collector being inserted inside the second sampling port.

5. The blood gas analyzer according to claim 4, wherein: the sample collector is provided with a sample.

6. The blood gas analyzer according to claim 5, wherein one end of the sampling needle is inserted into the sample collector through the main passage, and the other end is connected to the front detector, and the sampling needle has a pinhole.

The method of using the blood gas analyzer according to any one of claims 1 to 6, further comprising the steps of: S1, determining a first standard value: opening the sixth electromagnetic valve, the first pump body passing through the flow path The tube extracts the first reagent in the first reagent bag; when the liquid detector detects the first reagent, closes the sixth electromagnetic valve, opens the third electromagnetic valve, and the first reagent enters the detection membrane tube; when the rear detector detects the first When a reagent is used, the first pump body stops rotating, the third solenoid valve is closed, the electrode starts the test, and the test data is stored in the memory as the first standard value; then the third solenoid valve is opened, and the first pump body will flow The first reagent in the road is drawn into the waste bag;

S2, determining a second standard value: opening the fifth electromagnetic valve, the first pump body extracts the second reagent in the second reagent bag through the flow path tube; when the liquid detector detects the second reagent, closes the fifth electromagnetic valve, opens a third solenoid valve, the second reagent enters the detection membrane tube; when the second detector detects the second reagent, the first pump body stops rotating, the electrode starts testing, and the test data is stored in the memory as a second standard Value; then opening the third solenoid valve, the first pump body draws the second reagent in the flow path into the waste bag; S3, deproteinizing: opening the fourth electromagnetic valve, the first pump body extracts the deproteinizing liquid in the third reagent bag through the flow path tube; when the liquid detector detects the deproteinizing liquid, the first pump body continues to rotate counterclockwise Then, the fourth electromagnetic valve is closed, the third electromagnetic valve is opened, and the deproteinized liquid enters the detection membrane tube; when the deproteinized liquid is detected by the rear detector, the first pump body continues to rotate, and when the deproteinized liquid begins to enter the waste liquid bag When the third electromagnetic valve is closed, the deproteinized liquid fully reacts with the residual blood protein in the flow path; finally, the first pump body rotates, and the deproteinized waste liquid in the flow path tube is drawn into the waste liquid bag;

8. The method of using a blood gas analyzer according to claim 7, wherein: in the step S1, the pinhole of the sampling needle is located at the first sampling port, and the first reagent flows through the first channel, and enters from the pinhole. In the sampling needle, in the step S2, the pinhole of the sampling needle is located at the first sampling port, and the second reagent flows through the first channel, and enters the sampling needle from the pinhole.

9. The method of using a blood gas analyzer according to claim 8, wherein: in step S4, the bottle mouth of the sample collector is inserted into the second sampling port, and the sampling needle is inserted into the sample collector through the main channel, and the needle is passed through the needle. The well draws the sample from the sample collector.