WO2014074797A8 - Ultra low density pulmonary powders - Google Patents
Ultra low density pulmonary powders Download PDFInfo
- Publication number
- WO2014074797A8 WO2014074797A8 PCT/US2013/069107 US2013069107W WO2014074797A8 WO 2014074797 A8 WO2014074797 A8 WO 2014074797A8 US 2013069107 W US2013069107 W US 2013069107W WO 2014074797 A8 WO2014074797 A8 WO 2014074797A8
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- low density
- ultra low
- powders
- pulmonary powders
- density pulmonary
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4833—Encapsulating processes; Filling of capsules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
- A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
- A61J3/074—Filling capsules; Related operations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
- A61K31/198—Alpha-aminoacids, e.g. alanine, edetic acids [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1611—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B1/00—Packaging fluent solid material, e.g. powders, granular or loose fibrous material, loose masses of small articles, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
- B65B1/04—Methods of, or means for, filling the material into the containers or receptacles
- B65B1/16—Methods of, or means for, filling the material into the containers or receptacles by pneumatic means, e.g. by suction
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B1/00—Packaging fluent solid material, e.g. powders, granular or loose fibrous material, loose masses of small articles, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
- B65B1/20—Reducing volume of filled material
- B65B1/26—Reducing volume of filled material by pneumatic means, e.g. suction
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B1/00—Packaging fluent solid material, e.g. powders, granular or loose fibrous material, loose masses of small articles, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
- B65B1/30—Devices or methods for controlling or determining the quantity or quality or the material fed or filled
- B65B1/36—Devices or methods for controlling or determining the quantity or quality or the material fed or filled by volumetric devices or methods
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B63/00—Auxiliary devices, not otherwise provided for, for operating on articles or materials to be packaged
- B65B63/02—Auxiliary devices, not otherwise provided for, for operating on articles or materials to be packaged for compressing or compacting articles or materials prior to wrapping or insertion in containers or receptacles
- B65B63/028—Auxiliary devices, not otherwise provided for, for operating on articles or materials to be packaged for compressing or compacting articles or materials prior to wrapping or insertion in containers or receptacles by pneumatic means
Abstract
Priority Applications (18)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BR112015010601-3A BR112015010601B1 (en) | 2012-11-09 | 2013-11-06 | PHARMACEUTICAL COMPOSITION AND USE OF THE COMPOSITION |
MX2015005768A MX371008B (en) | 2012-11-09 | 2013-11-08 | Ultra low density pulmonary powders. |
ES13852608T ES2880271T3 (en) | 2012-11-09 | 2013-11-08 | Ultra low density lung powders |
KR1020217039998A KR20210152020A (en) | 2012-11-09 | 2013-11-08 | Ultra low density pulmonary powders |
AU2013342248A AU2013342248B2 (en) | 2012-11-09 | 2013-11-08 | Ultra low density pulmonary powders |
KR1020157015346A KR102337781B1 (en) | 2012-11-09 | 2013-11-08 | Ultra low density pulmonary powders |
RU2015121091A RU2670987C2 (en) | 2012-11-09 | 2013-11-08 | Ultra low density inhalation powders |
SG11201503547TA SG11201503547TA (en) | 2012-11-09 | 2013-11-08 | Ultra low density pulmonary powders |
CN201380069936.3A CN105120843A (en) | 2012-11-09 | 2013-11-08 | Ultra low density pulmonary powders |
JP2015541917A JP6348501B2 (en) | 2012-11-09 | 2013-11-08 | Very low density lung powder |
EP13852608.2A EP2916826B1 (en) | 2012-11-09 | 2013-11-08 | Ultra low density pulmonary powders |
CA2890459A CA2890459C (en) | 2012-11-09 | 2013-11-08 | Ultra low density pulmonary powders |
EP21170515.7A EP3957301A1 (en) | 2012-11-09 | 2013-11-08 | Ultra low density pulmonary powders |
US14/707,071 US9539211B2 (en) | 2012-11-09 | 2015-05-08 | Ultra low density pulmonary powders |
ZA2015/04060A ZA201504060B (en) | 2012-11-09 | 2015-06-05 | Ultra low density pulmonary powders |
HK16100777.1A HK1212884A1 (en) | 2012-11-09 | 2016-01-22 | Ultra low density pulmonary powders |
HK16101182.8A HK1213187A1 (en) | 2012-11-09 | 2016-02-02 | Ultra low density pulmonary powders |
AU2018222983A AU2018222983B2 (en) | 2012-11-09 | 2018-08-30 | Ultra Low Density Pulmonary Powders |
Applications Claiming Priority (12)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261724781P | 2012-11-09 | 2012-11-09 | |
US61/724,781 | 2012-11-09 | ||
US13/679,245 US8545878B1 (en) | 2012-11-09 | 2012-11-16 | Capsules containing high doses of levodopa for pulmonary use |
US13/679,245 | 2012-11-16 | ||
US13/945,160 | 2013-07-18 | ||
US13/945,160 US8685442B1 (en) | 2012-11-09 | 2013-07-18 | Capsules containing high doses of levodopa for pulmonary use |
US201361884436P | 2013-09-30 | 2013-09-30 | |
US201361884319P | 2013-09-30 | 2013-09-30 | |
US201361884315P | 2013-09-30 | 2013-09-30 | |
US61/884,436 | 2013-09-30 | ||
US61/884,315 | 2013-09-30 | ||
US61/884,319 | 2013-09-30 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US14/707,071 Continuation US9539211B2 (en) | 2012-11-09 | 2015-05-08 | Ultra low density pulmonary powders |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2014074797A1 WO2014074797A1 (en) | 2014-05-15 |
WO2014074797A8 true WO2014074797A8 (en) | 2014-06-26 |
Family
ID=50685169
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2013/069107 WO2014074797A1 (en) | 2012-11-09 | 2013-11-06 | Ultra low density pulmonary powders |
PCT/US2013/069102 WO2014074795A1 (en) | 2012-11-09 | 2013-11-08 | High dose levodopa capsules for pulmonary use |
PCT/US2013/069104 WO2014074796A1 (en) | 2012-11-09 | 2013-11-08 | Dosator for filling a capsule with powder |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2013/069102 WO2014074795A1 (en) | 2012-11-09 | 2013-11-08 | High dose levodopa capsules for pulmonary use |
PCT/US2013/069104 WO2014074796A1 (en) | 2012-11-09 | 2013-11-08 | Dosator for filling a capsule with powder |
Country Status (19)
Country | Link |
---|---|
US (3) | US9539211B2 (en) |
EP (5) | EP2925611B1 (en) |
JP (6) | JP6836834B2 (en) |
KR (6) | KR102257164B1 (en) |
CN (4) | CN105120843A (en) |
AU (6) | AU2013342248B2 (en) |
BR (2) | BR112015010601B1 (en) |
CA (3) | CA2890454C (en) |
DK (1) | DK2916821T3 (en) |
ES (2) | ES2844153T3 (en) |
HK (5) | HK1212884A1 (en) |
MX (3) | MX371008B (en) |
NZ (4) | NZ708684A (en) |
PL (1) | PL2916821T3 (en) |
PT (1) | PT2916821T (en) |
RU (2) | RU2670987C2 (en) |
SG (5) | SG11201503547TA (en) |
WO (3) | WO2014074797A1 (en) |
ZA (2) | ZA201504058B (en) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR112015010601B1 (en) | 2012-11-09 | 2022-07-19 | Civitas Therapeutics, Inc. | PHARMACEUTICAL COMPOSITION AND USE OF THE COMPOSITION |
MA40910A (en) * | 2014-11-07 | 2017-09-12 | Civitas Therapeutics Inc | RAPAMYCIN POWDERS FOR PULMONARY ADMINISTRATION |
KR101748796B1 (en) * | 2015-09-30 | 2017-06-19 | 한미약품 주식회사 | Inhalation capsule with enhanced delivery rate of active ingredients |
CN108700448B (en) * | 2016-02-06 | 2020-08-04 | 德国翰辉包装机械有限责任公司 | Pricking pipette |
ITUA20163077A1 (en) * | 2016-05-02 | 2017-11-02 | Mg 2 Srl | POWER SUPPLY GROUP FOR DETERMINATION OF GRANULES, IN PARTICULAR MICROGRANULES, IN CAPSULES |
GB2550961A (en) * | 2016-06-03 | 2017-12-06 | Res Center Pharmaceutical Engineering Gmbh | Apparatus for dosing a solid material into at least one receptacle |
CN106394953A (en) * | 2016-06-24 | 2017-02-15 | 湖南千山制药机械股份有限公司 | Vacuum filling system |
WO2019060797A1 (en) | 2017-09-22 | 2019-03-28 | Teva Branded Pharmaceutical Products R&D, Inc. | Method for manufacture of inhalation powders |
WO2019067708A1 (en) | 2017-09-27 | 2019-04-04 | Teva Branded Pharmaceutical Products R&D, Inc. | Method for particle size reduction |
ES2953293T3 (en) | 2018-08-07 | 2023-11-10 | Norton Waterford Ltd | Application of Raman Spectroscopy for the Manufacturing of Inhalation Powders |
EP3608015B1 (en) * | 2018-08-08 | 2021-10-06 | Harro Höfliger Verpackungsmaschinen GmbH | Powder provision device for a powder metering apparatus |
CN108995838A (en) * | 2018-09-10 | 2018-12-14 | 江西克莱威纳米碳材料有限公司 | A kind of powder tinning system |
CN109178367B (en) * | 2018-10-15 | 2021-01-26 | 楚天科技股份有限公司 | Filling head and filling device for powder split charging |
CN110040519A (en) * | 2019-04-30 | 2019-07-23 | 裕东(中山)机械工程有限公司 | A kind of quantitatively Dual-Phrase Distribution of Gas olid conveying device and dose delivery system |
RU2716294C1 (en) * | 2019-10-04 | 2020-03-11 | Владимир Александрович Трусов | Tandem reflecting furnace for aluminum scrap remelting |
IT202000008962A1 (en) * | 2020-04-24 | 2021-10-24 | Romaco Srl | EQUIPMENT FOR FILLING CONTAINERS WITH A POWDER MATERIAL |
CN116546980A (en) * | 2020-12-11 | 2023-08-04 | 江苏恒瑞医药股份有限公司 | Pharmaceutical composition for pulmonary delivery |
Family Cites Families (106)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2540059A (en) * | 1947-08-02 | 1951-01-30 | American Cyanamid Co | Method of and apparatus for measuring and filling powders volumetrically |
US3656518A (en) * | 1967-03-27 | 1972-04-18 | Perry Ind Inc | Method and apparatus for measuring and dispensing predetermined equal amounts of powdered material |
US3847191A (en) * | 1971-08-23 | 1974-11-12 | T Aronson | Means and methods for measuring and dispensing equal amounts of powdered material |
IT1069354B (en) * | 1976-03-05 | 1985-03-25 | Zanasi Nigris Spa | IMPROVEMENTS IN VOLUME DOSING UNITS |
IT1156553B (en) * | 1982-03-03 | 1987-02-04 | Mg 2 Spa | PROCEDURE FOR WITHDRAWING A PREFIXED QUANTITY OF POWDER FROM INSIDE A ROTATING CONTAINER AND FOR STORING SUCH QUANTITY INSIDE A BOTTOM OF A CONTAINER OF SHAPE OF ANY AND MACHINE WHICH OPERATES THAT PROCEDURE |
JPS59115201A (en) * | 1982-12-10 | 1984-07-03 | 武田薬品工業株式会社 | Treating machine for powdered and granular body |
IT1245757B (en) * | 1991-01-15 | 1994-10-14 | Mg 2 Spa | MACHINE FOR DOSING PHARMACEUTICAL PRODUCTS IN POWDER. |
US5111642A (en) * | 1991-01-23 | 1992-05-12 | Macofar S.P.A. | Machine for the dosage of powders in capsules, in particular for the pharmaceutical industry |
US5756123A (en) | 1994-12-01 | 1998-05-26 | Japan Elanco Co., Ltd. | Capsule shell |
US5826633A (en) * | 1996-04-26 | 1998-10-27 | Inhale Therapeutic Systems | Powder filling systems, apparatus and methods |
AU724503B2 (en) * | 1996-04-29 | 2000-09-21 | Dura Pharmaceuticals, Inc. | Methods of dry powder inhalation |
US5855913A (en) | 1997-01-16 | 1999-01-05 | Massachusetts Instite Of Technology | Particles incorporating surfactants for pulmonary drug delivery |
US6254854B1 (en) | 1996-05-24 | 2001-07-03 | The Penn Research Foundation | Porous particles for deep lung delivery |
US5985309A (en) | 1996-05-24 | 1999-11-16 | Massachusetts Institute Of Technology | Preparation of particles for inhalation |
US20020052310A1 (en) | 1997-09-15 | 2002-05-02 | Massachusetts Institute Of Technology The Penn State Research Foundation | Particles for inhalation having sustained release properties |
US6652837B1 (en) * | 1996-05-24 | 2003-11-25 | Massachusetts Institute Of Technology | Preparation of novel particles for inhalation |
USRE37053E1 (en) | 1996-05-24 | 2001-02-13 | Massachusetts Institute Of Technology | Particles incorporating surfactants for pulmonary drug delivery |
US6503480B1 (en) | 1997-05-23 | 2003-01-07 | Massachusetts Institute Of Technology | Aerodynamically light particles for pulmonary drug delivery |
US5874064A (en) | 1996-05-24 | 1999-02-23 | Massachusetts Institute Of Technology | Aerodynamically light particles for pulmonary drug delivery |
EP0971698A4 (en) * | 1996-12-31 | 2006-07-26 | Nektar Therapeutics | Aerosolized hydrophobic drug |
US7052678B2 (en) | 1997-09-15 | 2006-05-30 | Massachusetts Institute Of Technology | Particles for inhalation having sustained release properties |
US20030077227A1 (en) * | 1997-10-01 | 2003-04-24 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating disorders of the central nervous system |
US20040028735A1 (en) | 1997-11-14 | 2004-02-12 | Unchalee Kositprapa | Pharmaceutical formulation |
EP1069889B1 (en) * | 1998-04-09 | 2004-06-30 | Celanese Ventures GmbH | Partikulärer wirkstoffträger für die pulmonale applikation |
MA25590A1 (en) * | 1998-09-14 | 2002-12-31 | Inhale Therapeutic Syst | ACTIVE AGENT FOR DRY POWDER DELIVERY |
IT1304779B1 (en) * | 1998-12-03 | 2001-03-29 | Ima Spa | DISC AND PESTEL DISPENSER, INTERMITTENTLY OPERATING, SINGLE-SIDED, PARTICULARLY SUITABLE FOR PACKAGING DOSES |
US6858199B1 (en) | 2000-06-09 | 2005-02-22 | Advanced Inhalation Research, Inc. | High efficient delivery of a large therapeutic mass aerosol |
US6586008B1 (en) | 1999-08-25 | 2003-07-01 | Advanced Inhalation Research, Inc. | Use of simple amino acids to form porous particles during spray drying |
US7252840B1 (en) | 1999-08-25 | 2007-08-07 | Advanced Inhalation Research, Inc. | Use of simple amino acids to form porous particles |
GB9926335D0 (en) * | 1999-11-05 | 2000-01-12 | Powderject Res Ltd | Apparatus and method for dispensing small quantities of particles |
GB2356386A (en) | 1999-11-17 | 2001-05-23 | Tagra Biotechnologies Ltd | Microencapsulation |
US20030180352A1 (en) | 1999-11-23 | 2003-09-25 | Patel Mahesh V. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
GB0014082D0 (en) * | 2000-06-10 | 2000-08-02 | Glaxo Group Ltd | Method and apparatus for transferring a defined quantity of powder |
US6613308B2 (en) | 2000-09-19 | 2003-09-02 | Advanced Inhalation Research, Inc. | Pulmonary delivery in treating disorders of the central nervous system |
US6514482B1 (en) | 2000-09-19 | 2003-02-04 | Advanced Inhalation Research, Inc. | Pulmonary delivery in treating disorders of the central nervous system |
US20020122773A1 (en) * | 2000-12-20 | 2002-09-05 | Michel Pairet | Pharmaceutical compositions based on anticholinergics and dopamine agonists |
AU2002230993B2 (en) | 2000-12-29 | 2006-02-02 | Alkermes, Inc. | Particles for inhalation having sustained release properties |
US6766799B2 (en) | 2001-04-16 | 2004-07-27 | Advanced Inhalation Research, Inc. | Inhalation device |
US6848197B2 (en) * | 2001-04-18 | 2005-02-01 | Advanced Inhalation Research, Inc. | Control of process humidity to produce large, porous particles |
DE60223017T2 (en) * | 2001-04-20 | 2008-07-31 | Glaxo Group Ltd., Greenford | MEASURING METHOD FOR PARTICLE MATERIAL |
WO2002096422A2 (en) | 2001-05-25 | 2002-12-05 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Combination of a dopamine d2-receptor agonist and tiotropium or a derivative thereof for treating obstructive airways |
US6531153B2 (en) | 2001-05-29 | 2003-03-11 | Drugtech Corporation | Composition with sustained release of levodopa and carbidopa |
US7122143B2 (en) * | 2001-09-28 | 2006-10-17 | Mcneil-Ppc, Inc. | Methods for manufacturing dosage forms |
US6767200B2 (en) * | 2001-09-28 | 2004-07-27 | Mcneil-Ppc, Inc. | Systems, methods and apparatuses for manufacturing dosage forms |
CA2465675C (en) * | 2001-11-20 | 2008-06-10 | Advanced Inhalation Research, Inc. | Improved particulate compositions for pulmonary delivery |
EP1487411B1 (en) | 2002-03-20 | 2019-01-02 | Civitas Therapeutics, Inc. | Inhalable sustained therapeutic formulations |
ES2609482T3 (en) * | 2002-03-20 | 2017-04-20 | Civitas Therapeutics, Inc. | Lung administration of levodopa |
US20110123574A1 (en) * | 2002-03-20 | 2011-05-26 | Alkermes, Inc. | Inhalable sustained therapeutic formulations |
JP4897198B2 (en) | 2002-03-20 | 2012-03-14 | アルカームズ,インコーポレイテッド | Perforation means for use with inhalation devices |
US7754242B2 (en) | 2002-03-20 | 2010-07-13 | Alkermes, Inc. | Inhalable sustained therapeutic formulations |
US7008644B2 (en) | 2002-03-20 | 2006-03-07 | Advanced Inhalation Research, Inc. | Method and apparatus for producing dry particles |
WO2003094900A1 (en) * | 2002-05-13 | 2003-11-20 | Alexza Molecular Delivery Corporation | Delivery of drug amines through an inhalation route |
CA2484950C (en) * | 2002-06-27 | 2011-05-24 | Nektar Therapeutics | Device and method for controlling the flow of a powder |
US6941980B2 (en) * | 2002-06-27 | 2005-09-13 | Nektar Therapeutics | Apparatus and method for filling a receptacle with powder |
US7947742B2 (en) | 2002-06-28 | 2011-05-24 | Civitas Therapeutics, Inc. | Inhalable epinephrine |
ITBO20020525A1 (en) * | 2002-08-08 | 2004-02-09 | Ima Spa | OPERATING MACHINE. |
AU2003288182A1 (en) * | 2002-11-26 | 2004-06-18 | Universiteit Gent | Process and apparatus for continuous wet granulation of power material |
US7763280B2 (en) | 2002-11-28 | 2010-07-27 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Tiotropium containing powder formulation for inhalation |
DE10255387A1 (en) * | 2002-11-28 | 2004-06-09 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | New tiotropium-containing powder formulation for inhalation |
JP2006522634A (en) * | 2003-04-14 | 2006-10-05 | ベクトゥラ・リミテッド | Device and pharmaceutical composition for improving administration efficiency |
DE20309279U1 (en) * | 2003-06-12 | 2004-10-21 | Harro Höfliger Verpackungsmaschinen GmbH | Filter piston unit for filling predetermined volumes of powdery materials into containers comprises a hollow cylindrical piston with a transverse slit and an opposing internal groove in its wall |
US7134459B2 (en) * | 2003-06-12 | 2006-11-14 | Symyx Technologies, Inc. | Methods and apparatus for mixing powdered samples |
WO2004112702A2 (en) | 2003-06-13 | 2004-12-29 | Advanced Inhalation Research, Inc. | Low dose pharmaceutical powders for inhalation |
SE0303269L (en) * | 2003-12-03 | 2005-06-04 | Microdrug Ag | Medical product |
BRPI0418276B8 (en) * | 2003-12-31 | 2021-05-25 | Cydex Pharmaceuticals Inc | inhalable liquid formulation comprising budesonide |
SE0401842D0 (en) * | 2004-07-12 | 2004-07-12 | Dizlin Medical Design Ab | Infusion and injection solution of levodopa |
GB0425758D0 (en) * | 2004-11-23 | 2004-12-22 | Vectura Ltd | Preparation of pharmaceutical compositions |
US20060216345A1 (en) | 2005-03-24 | 2006-09-28 | Sun Pharmaceutical Industries Limited | Oral pharmaceutical composition including paroxetine |
US20060222699A1 (en) | 2005-03-29 | 2006-10-05 | Jonathan Gilinski | Flavored vegetarian cellulose capsule and methods for producing said capsule. |
JP5694643B2 (en) * | 2005-08-05 | 2015-04-01 | スリーエム イノベイティブ プロパティズ カンパニー | Composition exhibiting improved fluidity |
AR055106A1 (en) | 2005-08-05 | 2007-08-08 | Osmotica Pharmaceutical Argent | SOLID PHARMACEUTICAL COMPOSITION OF EXTENDED LIBERATION CONTAINING CARBIDOPA AND LEVODOPA |
DE102005039765A1 (en) * | 2005-08-23 | 2007-03-01 | Robert Bosch Gmbh | sensing device |
GB0523576D0 (en) * | 2005-11-18 | 2005-12-28 | Theradeas Ltd | Drug composition and its use in therapy |
US20120128728A1 (en) * | 2005-12-28 | 2012-05-24 | Novartis Pharma Ag | Compositions Comprising Amphotericin B |
EP1803432B1 (en) * | 2005-12-29 | 2010-03-31 | MG 2 - S.r.l. | Machine for filling capsules with a product |
CN101453993A (en) * | 2006-04-03 | 2009-06-10 | 伊萨·奥迪迪 | Controlled release delivery device comprising an organosol coat |
US20080063722A1 (en) | 2006-09-08 | 2008-03-13 | Advanced Inhalation Research, Inc. | Composition of a Spray-Dried Powder for Pulmonary Delivery of a Long Acting Neuraminidase Inhibitor (LANI) |
US20080066739A1 (en) | 2006-09-20 | 2008-03-20 | Lemahieu Edward | Methods and systems of delivering medication via inhalation |
US20100168410A1 (en) | 2006-10-27 | 2010-07-01 | Pfizer Products Inc. | Hydroxypropyl Methyl Cellulose Hard Capsules and Process of Manufacture |
CA2673511A1 (en) | 2006-12-22 | 2008-07-03 | Combinatorx, Incorporated | Pharmaceutical compositions for treatment of parkinson's disease and related disorders |
AU2008258596B2 (en) | 2007-06-04 | 2013-02-14 | Egalet Ltd | Controlled release pharmaceutical compositions for prolonged effect |
US8496002B2 (en) | 2007-06-12 | 2013-07-30 | Civitas Therapeutics, Inc. | Powder inhaler devices |
PE20090907A1 (en) * | 2007-07-21 | 2009-08-05 | Boehringer Ingelheim Int | NEW POWDER DRUGS CONTAINING THOTROPE AND SALMETEROL, AS WELL AS LACTOSE AS AN EXCIPIENT |
WO2009026434A1 (en) | 2007-08-21 | 2009-02-26 | Alkermes, Inc. | Pulmonary pharmaceutical formulations |
GB2454480A (en) | 2007-11-07 | 2009-05-13 | Vectura Group Plc | Pulmonary inhalation of levodopa containing compositions in the treatment of Parkinsons disease and other central nervous system disorders |
CN102119026A (en) | 2008-06-13 | 2011-07-06 | 葛兰素集团有限公司 | Hydroxypropyl cellulose capsule shell |
US8485180B2 (en) * | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
CA2982550C (en) * | 2008-06-13 | 2020-08-25 | Mannkind Corporation | A dry powder inhaler and system for drug delivery |
US20110268666A1 (en) | 2008-09-29 | 2011-11-03 | Yissum Research Development Company of the Research University of Jerusalem, Ltd. | Novel gastroretentive delivery system |
IT1390803B1 (en) * | 2008-09-30 | 2011-10-19 | Mg2 Srl | EQUIPMENT FOR DOSING PULVERULATING OR GRANULAR MATERIALS IN CAPSULES OR SIMILAR |
US8399513B2 (en) | 2008-10-20 | 2013-03-19 | Xenoport, Inc. | Levodopa prodrug mesylate hydrate |
US20120135969A1 (en) * | 2008-11-27 | 2012-05-31 | Boehringer Ingelheim International Gmbh | Novel powdered crystalline medicines for inhalation |
RU2577698C2 (en) * | 2009-03-26 | 2016-03-20 | Пулмэтрикс, Инк. | Dry powder formulations and methods of treating pulmonary diseases |
US20120160944A1 (en) * | 2009-04-24 | 2012-06-28 | Aaron Dodd | Method for the production of commercial nanoparticle and micro particle powders |
IT1394027B1 (en) * | 2009-05-11 | 2012-05-25 | Mg 2 Srl | MACHINE FOR FILLING CAPSULES WITH PHARMACEUTICALS |
US8359815B2 (en) * | 2009-05-11 | 2013-01-29 | Mg 2—S.R.L. | Machine for filling capsules with pharmaceutical products |
GB0918450D0 (en) * | 2009-10-21 | 2009-12-09 | Innovata Ltd | Composition |
RU2445119C2 (en) * | 2010-05-25 | 2012-03-20 | Сергей Викторович Чепур | Pharmaceutical composition and method for pulmonary administration thereof |
US20120164233A1 (en) | 2010-07-30 | 2012-06-28 | Ranbaxy Laboratories Limited | Pulsatile release pharmaceutical formulation of dexlansoprazole |
CN105640925B (en) * | 2010-08-30 | 2019-08-16 | 普马特里克斯营业公司 | Dried powder formula and method for treating pulmonary disease |
TW201304822A (en) | 2010-11-15 | 2013-02-01 | Vectura Ltd | Compositions and uses |
KR102237007B1 (en) | 2012-10-22 | 2021-04-06 | 키비타스 테라퓨틱스, 인코포레이티드. | Reducing inter-patient variability of levodopa plasma concentrations |
NZ708414A (en) | 2012-10-22 | 2018-11-30 | Civitas Therapeutics Inc | Levodopa formulations for rapid relief of parkinson’s disease |
US8545878B1 (en) * | 2012-11-09 | 2013-10-01 | Civitas Therapeutics, Inc. | Capsules containing high doses of levodopa for pulmonary use |
BR112015010601B1 (en) | 2012-11-09 | 2022-07-19 | Civitas Therapeutics, Inc. | PHARMACEUTICAL COMPOSITION AND USE OF THE COMPOSITION |
EP3134077A4 (en) | 2014-04-21 | 2017-12-20 | Civitas Therapeutics, Inc. | Rapid relief of motor fluctuations in parkinson's disease |
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