WO2014137808A3 - Thermochromic polyvinyl alcohol based hydrogel artery - Google Patents

Thermochromic polyvinyl alcohol based hydrogel artery Download PDF

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Publication number
WO2014137808A3
WO2014137808A3 PCT/US2014/019421 US2014019421W WO2014137808A3 WO 2014137808 A3 WO2014137808 A3 WO 2014137808A3 US 2014019421 W US2014019421 W US 2014019421W WO 2014137808 A3 WO2014137808 A3 WO 2014137808A3
Authority
WO
WIPO (PCT)
Prior art keywords
blood vessel
artificial blood
linking
cross
polyvinyl alcohol
Prior art date
Application number
PCT/US2014/019421
Other languages
French (fr)
Other versions
WO2014137808A2 (en
Inventor
Euhnee CHO
Valentine KOZOV
Sukanya VARADHARAJAN
Steven N. Willard
Original Assignee
St. Jude Medical, Cardiology Division, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by St. Jude Medical, Cardiology Division, Inc. filed Critical St. Jude Medical, Cardiology Division, Inc.
Priority to EP14712084.4A priority Critical patent/EP2964278A2/en
Publication of WO2014137808A2 publication Critical patent/WO2014137808A2/en
Publication of WO2014137808A3 publication Critical patent/WO2014137808A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/01—Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue
    • A61B5/015—By temperature mapping of body part
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/507—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials for artificial blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B2010/0003—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements including means for analysis by an unskilled person
    • A61B2010/0006—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements including means for analysis by an unskilled person involving a colour change
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00017—Electrical control of surgical instruments
    • A61B2017/00022—Sensing or detecting at the treatment site
    • A61B2017/00084—Temperature

Abstract

A method of creating a thermochromic artificial blood vessel includes physically cross-linking a polyvinyl alcohol solution in a mold shaped to mimic a blood vessel to create an artificial blood vessel. The artificial tissue is then chemically cross-linked with a solution including a chemical cross-linking reagent. A coagulation solution is then applied to the artificial blood vessel to both inhibit the chemical cross-linking and promote physical cross-linking of the artificial blood vessel. The artificial blood vessel can be used to test an ablation catheter. The vessel, when heated by the ablation catheter, changes color and/or transparency at locations where the temperature of artificial blood vessel increases.
PCT/US2014/019421 2013-03-06 2014-02-28 Thermochromic polyvinyl alcohol based hydrogel artery WO2014137808A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP14712084.4A EP2964278A2 (en) 2013-03-06 2014-02-28 Thermochromic polyvinyl alcohol based hydrogel artery

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13/786,727 US9179997B2 (en) 2013-03-06 2013-03-06 Thermochromic polyvinyl alcohol based hydrogel artery
US13/786,727 2013-03-06

Publications (2)

Publication Number Publication Date
WO2014137808A2 WO2014137808A2 (en) 2014-09-12
WO2014137808A3 true WO2014137808A3 (en) 2014-10-30

Family

ID=50346107

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2014/019421 WO2014137808A2 (en) 2013-03-06 2014-02-28 Thermochromic polyvinyl alcohol based hydrogel artery

Country Status (3)

Country Link
US (1) US9179997B2 (en)
EP (1) EP2964278A2 (en)
WO (1) WO2014137808A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10147340B2 (en) * 2013-11-22 2018-12-04 Boston Scientific Scimed, Inc. Simulation module
JP7343873B2 (en) 2019-10-23 2023-09-13 国立大学法人横浜国立大学 biological model
JP7389430B2 (en) 2019-10-23 2023-11-30 国立大学法人横浜国立大学 Vascular lesion model and method for manufacturing the vascular lesion model
WO2022039255A1 (en) * 2020-08-20 2022-02-24 アトナープ株式会社 Implant, biomonitoring system, and biomanagement system

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Also Published As

Publication number Publication date
US9179997B2 (en) 2015-11-10
EP2964278A2 (en) 2016-01-13
WO2014137808A2 (en) 2014-09-12
US20140257275A1 (en) 2014-09-11

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