WO2014189780A3 - Apparatus and method for forming a nanofiber hydrogel composite - Google Patents

Apparatus and method for forming a nanofiber hydrogel composite Download PDF

Info

Publication number
WO2014189780A3
WO2014189780A3 PCT/US2014/038344 US2014038344W WO2014189780A3 WO 2014189780 A3 WO2014189780 A3 WO 2014189780A3 US 2014038344 W US2014038344 W US 2014038344W WO 2014189780 A3 WO2014189780 A3 WO 2014189780A3
Authority
WO
WIPO (PCT)
Prior art keywords
housing
platform
nozzle
variety
discharge
Prior art date
Application number
PCT/US2014/038344
Other languages
French (fr)
Other versions
WO2014189780A2 (en
Inventor
Catherine K. Kuo
Jeffrey P. Brown
Original Assignee
Tufts University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tufts University filed Critical Tufts University
Publication of WO2014189780A2 publication Critical patent/WO2014189780A2/en
Publication of WO2014189780A3 publication Critical patent/WO2014189780A3/en

Links

Classifications

    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01D—MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
    • D01D5/00—Formation of filaments, threads, or the like
    • D01D5/18—Formation of filaments, threads, or the like by means of rotating spinnerets
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01D—MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
    • D01D5/00—Formation of filaments, threads, or the like
    • D01D5/0007—Electro-spinning
    • D01D5/0061—Electro-spinning characterised by the electro-spinning apparatus

Abstract

A method for making an electrospun nano- or micro-fiber hydrogel composite includes a platform suspended within a housing and a motor connected to the housing or platform so as to cause rotation of the housing relative to the platform, or vice versa. The platform supports nozzles that are directed toward a collector formed on an interior surface of the housing. At least one nozzle is configured to discharge an electrospun fiber, and at least one other nozzle is configured to discharge a gellable solution. After multiple revolutions of the housing, the electrospun fiber forms a scaffold that is interspersed with hydrogel and the other discharged substances. This novel method of fabrication yields composites consisting of a variety of materials, structures, biological and chemical components, and mechanical properties that will have utility in a variety of fields including regenerative medicine, tissue engineering, drug delivery, wound healing and more.
PCT/US2014/038344 2013-05-20 2014-05-16 Apparatus and method for forming a nanofiber hydrogel composite WO2014189780A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361825191P 2013-05-20 2013-05-20
US61/825,191 2013-05-20

Publications (2)

Publication Number Publication Date
WO2014189780A2 WO2014189780A2 (en) 2014-11-27
WO2014189780A3 true WO2014189780A3 (en) 2015-01-15

Family

ID=51934321

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2014/038344 WO2014189780A2 (en) 2013-05-20 2014-05-16 Apparatus and method for forming a nanofiber hydrogel composite

Country Status (1)

Country Link
WO (1) WO2014189780A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ308167B6 (en) * 2014-12-17 2020-02-05 Technická univerzita v Liberci A process for manufacturing polymeric fibres with a diameter of 100 nm to 10 μm, and a process for producing a linear, planar or spatial formation containing these polymeric fibres
CN106567144A (en) * 2016-11-11 2017-04-19 北京化工大学 Three-dimensional coaxial spinning apparatus
US20230190997A1 (en) 2017-06-26 2023-06-22 Evolved By Nature, Inc. Silk-hyaluronic acid based tissue filers and methods of using the same
CN107456609A (en) * 2017-07-17 2017-12-12 浙江大学 The preparation method of directionality biology micro nanometer fiber support quick preparation device and micro nanometer fiber support
CN107299400A (en) * 2017-07-17 2017-10-27 浙江大学 The preparation method of swinging directionality composite micro-nano rice fiber preparation facilities and composite micro-nano rice fiber

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060228435A1 (en) * 2004-04-08 2006-10-12 Research Triangle Insitute Electrospinning of fibers using a rotatable spray head
US20080237934A1 (en) * 2005-05-03 2008-10-02 The University Of Akron Method and Device For Producing Electrospun Fibers and Fibers Produced Thereby
US20110156319A1 (en) * 2008-10-02 2011-06-30 Takahiro Kurokawa Method and apparatus for producing nanofibers
US20120034461A1 (en) * 2009-03-31 2012-02-09 The Science And Technology Facilities Council Electrospinning nozzle
US20120040461A1 (en) * 2009-02-23 2012-02-16 Beachley Vince Z Fabrication of nanofiber reinforced structures for tissue engineering
US20120304613A1 (en) * 2011-02-07 2012-12-06 Ed Peno Split fiber producing devices and methods for the production of microfibers and nanofibers

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060228435A1 (en) * 2004-04-08 2006-10-12 Research Triangle Insitute Electrospinning of fibers using a rotatable spray head
US20080237934A1 (en) * 2005-05-03 2008-10-02 The University Of Akron Method and Device For Producing Electrospun Fibers and Fibers Produced Thereby
US20110156319A1 (en) * 2008-10-02 2011-06-30 Takahiro Kurokawa Method and apparatus for producing nanofibers
US20120040461A1 (en) * 2009-02-23 2012-02-16 Beachley Vince Z Fabrication of nanofiber reinforced structures for tissue engineering
US20120034461A1 (en) * 2009-03-31 2012-02-09 The Science And Technology Facilities Council Electrospinning nozzle
US20120304613A1 (en) * 2011-02-07 2012-12-06 Ed Peno Split fiber producing devices and methods for the production of microfibers and nanofibers

Also Published As

Publication number Publication date
WO2014189780A2 (en) 2014-11-27

Similar Documents

Publication Publication Date Title
WO2014189780A3 (en) Apparatus and method for forming a nanofiber hydrogel composite
Badrossamay et al. Nanofiber assembly by rotary jet-spinning
WO2012006072A3 (en) Air impedance electrospinning for controlled porosity
WO2018104498A3 (en) Hollow fibre membrane with improved separating efficiency, and production of a hollow fibre membrane with improved separating efficiency
WO2014100213A3 (en) High temperature melt integrity battery separators via spinning
CL2013003236A1 (en) Method for the production of a precursor fiber containing lignin for the production of carbon fibers comprising a solution with at least one type of lignin and a fiber-forming polymer in at least one solvent and then transferred to a coagulation bath by the extrusion of the solution through a spinning nozzle; precursor fiber; and carbon fibers
WO2014082611A8 (en) Fibres based on hydrophobized derivatives of hyaluronan, method of their preparation and use, textiles on base thereof and use thereof
WO2011116848A3 (en) Multi-component fibers produced using a rotational spinning method
EP2108718A3 (en) Process for manufacturing organic fibers containing inorganic component and nonwoven fabric containing the same
WO2009133059A3 (en) Nanofiber matrices formed from electrospun hyperbranched polymers
FI20115570L (en) Process for the manufacture of natural fiber composite materials, products obtained and processes for application thereof
EP2106811A3 (en) Scaffold for tissue engineering and production method thereof
MX2017012400A (en) Method for manufacturing drug-containing biodegradable fiber material by electrospinning.
PH12014501472A1 (en) Fiber composition comprising 1,3-glucan and a method of preparing same
EP2505213A3 (en) System and method for formation of biodegradable ultra-porous hollow fibers and use thereof
JP2016216861A5 (en) Production method of hydrogel fiber, hydrogel fiber and material produced by the production method
EA201400004A1 (en) PRODUCTS, INCLUDING MULTICOMPONENT FIBERS AND PARTICLES, AND METHODS OF THEIR MANUFACTURE AND USE
BR112014017052A2 (en) process for preparing water-absorbent polymeric particles, water-absorbent polymeric particles and their use, composite and their use, process for the production of composite, foams, molded articles, fibers
FI20135638A (en) Process for the treatment of heavy residues, derived from materials of biological origin, and for the production of liquid fuel
EP3198673A4 (en) Polymer solution, fiber mat, and nanofiber membrane-electrode-assembly therewith, and method of fabricating same
Li et al. Elastic antibacterial membranes comprising particulate laden fibers for wound healing applications
WO2019086377A3 (en) Preparation of carbon fibers from lignin/pva precursor fibers
Ngadiman et al. Effect of electrospinning parameters setting towards fiber diameter
WO2012170732A3 (en) Medicament delivery systems
AR099556A1 (en) IMPLANT CONTAINING FGF-18

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 14801424

Country of ref document: EP

Kind code of ref document: A2

122 Ep: pct application non-entry in european phase

Ref document number: 14801424

Country of ref document: EP

Kind code of ref document: A2