WO2015094576A3 - Methods and systems for improving the reliability of orthogonally redundant glucose sensors - Google Patents

Methods and systems for improving the reliability of orthogonally redundant glucose sensors Download PDF

Info

Publication number
WO2015094576A3
WO2015094576A3 PCT/US2014/066794 US2014066794W WO2015094576A3 WO 2015094576 A3 WO2015094576 A3 WO 2015094576A3 US 2014066794 W US2014066794 W US 2014066794W WO 2015094576 A3 WO2015094576 A3 WO 2015094576A3
Authority
WO
WIPO (PCT)
Prior art keywords
sensor
sensors
electrochemical
optical
integrity checks
Prior art date
Application number
PCT/US2014/066794
Other languages
French (fr)
Other versions
WO2015094576A2 (en
Inventor
Andrea Varsavsky
Xiaolong Li
Mike C. Liu
Yuxiang Zhong
Ning Yang
Original Assignee
Medtronic Minimed, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medtronic Minimed, Inc. filed Critical Medtronic Minimed, Inc.
Priority to KR1020167019352A priority Critical patent/KR102250989B1/en
Priority to AU2014367039A priority patent/AU2014367039B2/en
Priority to JP2016539982A priority patent/JP6339204B2/en
Priority to EP14816501.2A priority patent/EP3082597B1/en
Priority to CN201480075582.8A priority patent/CN106028932B/en
Priority to EP20179623.2A priority patent/EP3733065B1/en
Priority to CN201910167742.6A priority patent/CN109984753B/en
Priority to CA2931955A priority patent/CA2931955C/en
Publication of WO2015094576A2 publication Critical patent/WO2015094576A2/en
Publication of WO2015094576A3 publication Critical patent/WO2015094576A3/en
Priority to AU2019226130A priority patent/AU2019226130B2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0004—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by the type of physiological signal transmitted
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14503—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • A61B5/14556—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases by fluorescence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/1459—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters invasive, e.g. introduced into the body by a catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • A61B5/1473—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1495—Calibrating or testing of in-vivo probes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
    • A61B5/4839—Diagnosis combined with treatment in closed-loop systems or methods combined with drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7221—Determining signal validity, reliability or quality
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7271—Specific aspects of physiological measurement analysis
    • A61B5/7278—Artificial waveform generation or derivation, e.g. synthesising signals from measured signals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
    • A61M5/1723—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/005—Enzyme electrodes involving specific analytes or enzymes
    • C12Q1/006—Enzyme electrodes involving specific analytes or enzymes for glucose
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/59—Transmissivity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84—Systems specially adapted for particular applications
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/27—Association of two or more measuring systems or cells, each measuring a different parameter, where the measurement results may be either used independently, the systems or cells being physically associated, or combined to produce a value for a further parameter
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3274—Corrective measures, e.g. error detection, compensation for temperature or hematocrit, calibration
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/4163—Systems checking the operation of, or calibrating, the measuring apparatus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/66—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
    • A61B2560/02—Operational features
    • A61B2560/0223—Operational features of calibration, e.g. protocols for calibrating sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
    • A61B2560/02—Operational features
    • A61B2560/0223—Operational features of calibration, e.g. protocols for calibrating sensors
    • A61B2560/0238—Means for recording calibration data
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/06—Arrangements of multiple sensors of different types
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
    • A61M5/1723—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure
    • A61M2005/1726—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure the body parameters being measured at, or proximate to, the infusion site
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3306—Optical measuring means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/35—Communication
    • A61M2205/3576—Communication with non implanted data transmission devices, e.g. using external transmitter or receiver
    • A61M2205/3584—Communication with non implanted data transmission devices, e.g. using external transmitter or receiver using modem, internet or bluetooth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/35—Communication
    • A61M2205/3576—Communication with non implanted data transmission devices, e.g. using external transmitter or receiver
    • A61M2205/3592—Communication with non implanted data transmission devices, e.g. using external transmitter or receiver using telemetric means, e.g. radio or optical transmission
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers
    • A61M2205/502—User interfaces, e.g. screens or keyboards
    • A61M2205/505—Touch-screens; Virtual keyboard or keypads; Virtual buttons; Soft keys; Mouse touches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers
    • A61M2205/52—General characteristics of the apparatus with microprocessors or computers with memories providing a history of measured variating parameters of apparatus or patient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00—Measuring parameters of the user
    • A61M2230/005—Parameter used as control input for the apparatus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00—Measuring parameters of the user
    • A61M2230/20—Blood composition characteristics
    • A61M2230/201—Glucose concentration
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/12—Circuits of general importance; Signal processing
    • G01N2201/127—Calibration; base line adjustment; drift compensation

Abstract

Methods and systems for sensor calibration and sensor glucose (SG) fusion are used advantageously to improve the accuracy and reliability of orthogonally redundant glucose sensor devices, which may include optical and electrochemical glucose sensors. Calibration for both sensors may be achieved via fixed-offset and/or dynamic regression methodologies, depending, e.g., on sensor stability and Isig-Ratio pair correlation. For SG fusion, respective integrity checks may be performed for SG values from the optical and electrochemical sensors, and the SG values calibrated if the integrity checks are passed. Integrity checks may include checking for sensitivity loss, noise, and drift. If the integrity checks are failed, in-line sensor mapping between the electrochemical and optical sensors may be performed prior to calibration. The electrochemical and optical SG values may be weighted (as a function of the respective sensor's overall reliability index (RI)) and the weighted SGs combined to obtain a single, fused SG value.
PCT/US2014/066794 2013-12-16 2014-11-21 Methods and systems for improving the reliability of orthogonally redundant sensors WO2015094576A2 (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
KR1020167019352A KR102250989B1 (en) 2013-12-16 2014-11-21 Methods and systems for improving the reliability of orthogonally redundant glucose sensors
AU2014367039A AU2014367039B2 (en) 2013-12-16 2014-11-21 Methods and systems for improving the reliability of orthogonally redundant glucose sensors
JP2016539982A JP6339204B2 (en) 2013-12-16 2014-11-21 Method and system for improving the reliability of orthogonal redundant sensors
EP14816501.2A EP3082597B1 (en) 2013-12-16 2014-11-21 Methods and systems for improving the reliability of orthogonally redundant glucose sensors
CN201480075582.8A CN106028932B (en) 2013-12-16 2014-11-21 For improving the method and system of the reliability of orthogonal redundancy sensor
EP20179623.2A EP3733065B1 (en) 2013-12-16 2014-11-21 Method and system for calibrating orthogonally redundant sensor devices
CN201910167742.6A CN109984753B (en) 2013-12-16 2014-11-21 Method and system for improving reliability of orthogonally redundant sensors
CA2931955A CA2931955C (en) 2013-12-16 2014-11-21 Methods and systems for improving the reliability of orthogonally redundant sensors
AU2019226130A AU2019226130B2 (en) 2013-12-16 2019-09-02 Methods and systems for improving the reliability of orthogonally redundant sensors

Applications Claiming Priority (12)

Application Number Priority Date Filing Date Title
US201361916632P 2013-12-16 2013-12-16
US61/916,632 2013-12-16
US14/260,948 2014-04-24
US14/260,755 US9603561B2 (en) 2013-12-16 2014-04-24 Methods and systems for improving the reliability of orthogonally redundant sensors
US14/261,043 2014-04-24
US14/260,948 US9943256B2 (en) 2013-12-16 2014-04-24 Methods and systems for improving the reliability of orthogonally redundant sensors
US14/260,755 2014-04-24
US14/261,077 US20150164385A1 (en) 2013-12-16 2014-04-24 Methods and systems for improving the reliability of orthogonally redundant sensors
US14/261,043 US9649059B2 (en) 2013-12-16 2014-04-24 Methods and systems for improving the reliability of orthogonally redundant sensors
US14/261,077 2014-04-24
US14/261,011 US9649058B2 (en) 2013-12-16 2014-04-24 Methods and systems for improving the reliability of orthogonally redundant sensors
US14/261,011 2014-04-24

Publications (2)

Publication Number Publication Date
WO2015094576A2 WO2015094576A2 (en) 2015-06-25
WO2015094576A3 true WO2015094576A3 (en) 2015-08-13

Family

ID=53366993

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2014/066794 WO2015094576A2 (en) 2013-12-16 2014-11-21 Methods and systems for improving the reliability of orthogonally redundant sensors

Country Status (8)

Country Link
US (15) US9649059B2 (en)
EP (2) EP3733065B1 (en)
JP (3) JP6339204B2 (en)
KR (1) KR102250989B1 (en)
CN (4) CN109984754A (en)
AU (2) AU2014367039B2 (en)
CA (2) CA2931955C (en)
WO (1) WO2015094576A2 (en)

Families Citing this family (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060281187A1 (en) 2005-06-13 2006-12-14 Rosedale Medical, Inc. Analyte detection devices and methods with hematocrit/volume correction and feedback control
DK1762259T3 (en) 2005-09-12 2011-01-03 Unomedical As Infusion set insertion device with a first and a second spring assembly
EP3461406A1 (en) 2005-09-30 2019-04-03 Intuity Medical, Inc. Multi-site body fluid sampling and analysis cartridge
US9833183B2 (en) 2008-05-30 2017-12-05 Intuity Medical, Inc. Body fluid sampling device—sampling site interface
CA2726067C (en) 2008-06-06 2020-10-20 Intuity Medical, Inc. Detection meter and mode of operation
EP2506768B1 (en) 2009-11-30 2016-07-06 Intuity Medical, Inc. Calibration material delivery devices and methods
CA2792138A1 (en) 2010-03-30 2011-10-06 Unomedical A/S Medical device
US10194938B2 (en) 2011-03-14 2019-02-05 UnoMedical, AS Inserter system with transport protection
EP3750480B1 (en) 2011-08-03 2022-02-02 Intuity Medical, Inc. Body fluid sampling arrangement
US11197689B2 (en) 2011-10-05 2021-12-14 Unomedical A/S Inserter for simultaneous insertion of multiple transcutaneous parts
EP2583715A1 (en) 2011-10-19 2013-04-24 Unomedical A/S Infusion tube system and method for manufacture
US11478158B2 (en) 2013-05-23 2022-10-25 Medibotics Llc Wearable ring of optical biometric sensors
US9649059B2 (en) 2013-12-16 2017-05-16 Medtronic Minimed, Inc. Methods and systems for improving the reliability of orthogonally redundant sensors
US10872048B2 (en) * 2014-01-13 2020-12-22 Senseonics, Incorporated Remotely-powered sensing system with multiple sensing devices
US20160007935A1 (en) * 2014-03-19 2016-01-14 Massachusetts Institute Of Technology Methods and apparatus for measuring physiological parameters
US20160029970A1 (en) * 2014-07-31 2016-02-04 Lg Cns Co., Ltd. Apparatus and method for determining validity of biological data
US11035818B2 (en) * 2014-08-15 2021-06-15 Roche Diabetes Care, Inc. Blood glucose meter with low cost user interface having programmed graphic indicators
US10543314B2 (en) 2015-08-21 2020-01-28 Medtronic Minimed, Inc. Personalized parameter modeling with signal calibration based on historical data
CN113974619A (en) 2015-09-10 2022-01-28 德克斯康公司 Transcutaneous analyte sensors and monitors, calibrations thereof, and associated methods
US20170071512A1 (en) * 2015-09-10 2017-03-16 Dexcom, Inc. Transcutaneous analyte sensors and monitors, calibration thereof, and associated methods
US11357912B2 (en) 2016-01-19 2022-06-14 Unomedical A/S Cannula and infusion devices
KR20180105127A (en) 2016-01-29 2018-09-27 에프. 호프만-라 로슈 아게 Electrochemiluminescent method and apparatus for detecting an analyte in a liquid sample
EP4191423A1 (en) * 2016-09-20 2023-06-07 Senseonics, Incorporated Remotely-powered sensing system with multiple sensing devices
CN106596962B (en) * 2016-11-01 2018-07-03 武汉璟泓万方堂医药科技股份有限公司 A kind of CODE definite value modification methods based on the attenuation of blood sugar test paper test value
CN108281200A (en) * 2016-12-30 2018-07-13 上海移宇科技股份有限公司 A kind of method of the adjustment algorithm in dynamic blood sugar monitoring system and the dynamic blood sugar monitoring system of application this method
TWI668664B (en) * 2017-01-16 2019-08-11 華廣生技股份有限公司 Method for dynamic analyzing blood sugar level, system thereof and computer program product
US10543288B2 (en) * 2017-04-28 2020-01-28 Medtronic Minimed, Inc. Modified-dextrans for use in optical glucose assays
US10792378B2 (en) * 2017-04-28 2020-10-06 Medtronics Minimed, Inc. Using a blue-shifted reference dye in an optical glucose assay
WO2018204476A1 (en) * 2017-05-03 2018-11-08 Abbott Diabetes Care Inc. Systems, devices, and methods with duration-based adjustment of sensor data
CN108968976B (en) 2017-05-31 2022-09-13 心脏起搏器股份公司 Implantable medical device with chemical sensor
JP7158919B2 (en) * 2017-07-04 2022-10-24 アークレイ株式会社 Measuring device, measuring program and measuring method
KR101975198B1 (en) * 2017-07-24 2019-08-28 최규동 Hybride Continous Glucose Measuremrnt System
EP3438858A1 (en) 2017-08-02 2019-02-06 Diabeloop Closed-loop blood glucose control systems and methods
EP3440999B1 (en) * 2017-08-10 2023-03-08 Cardiac Pacemakers, Inc. Systems including electrolyte sensor fusion
CN109381195B (en) 2017-08-10 2023-01-10 心脏起搏器股份公司 Systems and methods including electrolyte sensor fusion
CN109419515B (en) 2017-08-23 2023-03-24 心脏起搏器股份公司 Implantable chemical sensor with staged activation
US11445951B2 (en) * 2017-09-13 2022-09-20 Medtronic Minimed, Inc. Methods, systems, and devices for calibration and optimization of glucose sensors and sensor output
CN109864746B (en) 2017-12-01 2023-09-29 心脏起搏器股份公司 Multimode analyte sensor for medical devices
FR3074590B1 (en) * 2017-12-04 2023-03-17 Soc Air France METHOD FOR PREDICTING AN MALFUNCTION OF ONE OR MORE EQUIPMENT OF A SET
CN109864747B (en) 2017-12-05 2023-08-25 心脏起搏器股份公司 Multimode analyte sensor optoelectronic interface
US20190175082A1 (en) * 2017-12-13 2019-06-13 Medtronic Minimed, Inc. Pseudo-orthogonal redundant glucose sensors, systems, and methods
US11471082B2 (en) * 2017-12-13 2022-10-18 Medtronic Minimed, Inc. Complex redundancy in continuous glucose monitoring
US11213230B2 (en) * 2017-12-13 2022-01-04 Medtronic Minimed, Inc. Optional sensor calibration in continuous glucose monitoring
US11504070B2 (en) 2018-02-23 2022-11-22 Samsung Electronics Co., Ltd. Apparatus and method for estimation concentration of blood compound
KR102061810B1 (en) * 2018-03-23 2020-01-02 단국대학교 산학협력단 System and Method for Processing Multi type Sensor Signal Based on Multi modal Deep Learning
EP3574830B1 (en) * 2018-05-30 2023-12-20 Sony Group Corporation Method and device for blood glucose level monitoring
KR102179203B1 (en) * 2018-07-09 2020-11-16 주식회사 필로시스 Device and method to determine blood glucose sensing data
TWI671524B (en) 2018-10-01 2019-09-11 財團法人工業技術研究院 Liquid sensing apparatus and method of manufacturing the same
KR102578444B1 (en) * 2018-10-15 2023-09-14 엘지전자 주식회사 Needle-type Biosensor
US11701038B2 (en) * 2018-12-10 2023-07-18 Senseonics, Incorporated Assessement of performance of an implanted sensor
US11638563B2 (en) 2018-12-27 2023-05-02 Starkey Laboratories, Inc. Predictive fall event management system and method of using same
EP3946050A1 (en) * 2019-04-03 2022-02-09 Starkey Laboratories, Inc. Monitoring system and method of using same
US10725157B1 (en) * 2019-04-05 2020-07-28 Rockwell Automation Technologies, Inc. Industrial safety sensor
US20200330009A1 (en) 2019-04-22 2020-10-22 Dexcom, Inc. Preconnected analyte sensors
WO2020227573A1 (en) * 2019-05-09 2020-11-12 Waveform Technologies, Inc. Systems and methods for biosensor cross-calibration
EP3972672A4 (en) 2019-05-20 2023-06-21 Unomedical A/S Rotatable infusion device and methods thereof
JP7267865B2 (en) * 2019-07-19 2023-05-02 株式会社日立ハイテク Analysis device and analysis method
JP7173354B2 (en) * 2019-08-01 2022-11-16 株式会社村田製作所 Detection device, detection method and program
US11950902B2 (en) * 2019-08-02 2024-04-09 Bionime Corporation Micro biosensor and method for reducing measurement interference using the same
EP4084675A4 (en) * 2020-01-02 2023-05-24 Dexcom, Inc. End of life detection for analyte sensors experiencing progressive sensor decline
US11412962B1 (en) * 2020-03-25 2022-08-16 Tula Health, Inc. Devices, systems, and methods for identifying improving health for chronic health condition management
WO2022045872A1 (en) * 2020-08-25 2022-03-03 OSA Technology Sdn Bhd A system for calibrating medical devices and its method
JP7302556B2 (en) * 2020-09-03 2023-07-04 横河電機株式会社 measuring device
US20220125348A1 (en) 2020-10-22 2022-04-28 Medtronic Minimed, Inc. Detection of interferent in analyte sensing
CN112685492B (en) * 2020-12-30 2024-04-16 北京墨迹风云科技股份有限公司 Multi-source data fusion method and device
WO2023171356A1 (en) * 2022-03-07 2023-09-14 ソニーグループ株式会社 Patient monitoring system, patient monitoring method, and program
CN114626307B (en) * 2022-03-29 2023-04-07 电子科技大学 Distributed consistent target state estimation method based on variational Bayes
CN115060666B (en) * 2022-08-17 2022-11-15 北京英视睿达科技股份有限公司 Calibration method of water quality parameter sensor and water quality parameter measuring method and device
CN115407757B (en) * 2022-09-01 2023-06-20 南京理工大学 Heterogeneous sensor bimodal fault tolerance control method of digital twin-based multi-driver system

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080004536A1 (en) * 2006-06-30 2008-01-03 Baxi Amit S Method and apparatus for amplifying multiple signals using a single multiplexed amplifier channel with software controlled AC response
US20090030293A1 (en) * 2005-02-11 2009-01-29 The University Court Of The University Of Glasgow Sensing device, apparatus and system, and method for operating the same
US20090033482A1 (en) * 2007-07-31 2009-02-05 Abbott Diabetes Care, Inc. Method and apparatus for providing data processing and control in a medical communication system
US20090163855A1 (en) * 2007-12-24 2009-06-25 Medtronic Minimed, Inc. Infusion system with adaptive user interface
US20110319734A1 (en) * 2010-06-23 2011-12-29 Medtronic Minimed, Inc. Sensor systems having multiple probes and electrode arrays
US20120262298A1 (en) * 2011-04-15 2012-10-18 Dexcom, Inc. Advanced analyte sensor calibration and error detection
US20130060105A1 (en) * 2011-09-06 2013-03-07 Medtronic Minimed, Inc. Orthogonally Redundant Sensor Systems and Methods
WO2013184416A2 (en) * 2012-06-08 2013-12-12 Medtronic Minimed, Inc. Application of electrochemical impedance spectroscopy in sensor systems, devices, and related methods

Family Cites Families (105)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5338157B1 (en) 1992-09-09 1999-11-02 Sims Deltec Inc Systems and methods for communicating with ambulat
US4678408A (en) 1984-01-06 1987-07-07 Pacesetter Infusion, Ltd. Solenoid drive apparatus for an external infusion pump
US4685903A (en) 1984-01-06 1987-08-11 Pacesetter Infusion, Ltd. External infusion pump apparatus
US4562751A (en) 1984-01-06 1986-01-07 Nason Clyde K Solenoid drive apparatus for an external infusion pump
US4755173A (en) 1986-02-25 1988-07-05 Pacesetter Infusion, Ltd. Soft cannula subcutaneous injection set
US5080653A (en) 1990-04-16 1992-01-14 Pacesetter Infusion, Ltd. Infusion pump with dual position syringe locator
US5097122A (en) 1990-04-16 1992-03-17 Pacesetter Infusion, Ltd. Medication infusion system having optical motion sensor to detect drive mechanism malfunction
US5307263A (en) 1992-11-17 1994-04-26 Raya Systems, Inc. Modular microprocessor-based health monitoring system
US5832448A (en) 1996-10-16 1998-11-03 Health Hero Network Multiple patient monitoring system for proactive health management
US5956501A (en) 1997-01-10 1999-09-21 Health Hero Network, Inc. Disease simulation system and method
US5545143A (en) 1993-01-21 1996-08-13 T. S. I. Medical Device for subcutaneous medication delivery
US5299571A (en) 1993-01-22 1994-04-05 Eli Lilly And Company Apparatus and method for implantation of sensors
DK25793A (en) 1993-03-09 1994-09-10 Pharma Plast Int As Infusion set for intermittent or continuous administration of a therapeutic agent
US5536249A (en) 1994-03-09 1996-07-16 Visionary Medical Products, Inc. Pen-type injector with a microprocessor and blood characteristic monitor
US5391250A (en) 1994-03-15 1995-02-21 Minimed Inc. Method of fabricating thin film sensors
US5390671A (en) 1994-03-15 1995-02-21 Minimed Inc. Transcutaneous sensor insertion set
DE4415896A1 (en) 1994-05-05 1995-11-09 Boehringer Mannheim Gmbh Analysis system for monitoring the concentration of an analyte in the blood of a patient
US5482473A (en) 1994-05-09 1996-01-09 Minimed Inc. Flex circuit connector
IE72524B1 (en) 1994-11-04 1997-04-23 Elan Med Tech Analyte-controlled liquid delivery device and analyte monitor
US5697366A (en) 1995-01-27 1997-12-16 Optical Sensors Incorporated In situ calibration system for sensors located in a physiologic line
US5586553A (en) 1995-02-16 1996-12-24 Minimed Inc. Transcutaneous sensor insertion set
US5665065A (en) 1995-05-26 1997-09-09 Minimed Inc. Medication infusion device with blood glucose data input
US6011984A (en) 1995-11-22 2000-01-04 Minimed Inc. Detection of biological molecules using chemical amplification and optical sensors
US6766183B2 (en) 1995-11-22 2004-07-20 Medtronic Minimed, Inc. Long wave fluorophore sensor compounds and other fluorescent sensor compounds in polymers
US6607509B2 (en) 1997-12-31 2003-08-19 Medtronic Minimed, Inc. Insertion device for an insertion set and method of using the same
DE19717107B4 (en) 1997-04-23 2005-06-23 Disetronic Licensing Ag System of container and drive device for a piston, which is held in the container containing a drug fluid
US6186982B1 (en) 1998-05-05 2001-02-13 Elan Corporation, Plc Subcutaneous drug delivery device with improved filling system
US6558351B1 (en) 1999-06-03 2003-05-06 Medtronic Minimed, Inc. Closed loop system for controlling insulin infusion
US5954643A (en) 1997-06-09 1999-09-21 Minimid Inc. Insertion set for a transcutaneous sensor
US6246692B1 (en) 1998-02-03 2001-06-12 Broadcom Corporation Packet switching fabric using the segmented ring with resource reservation control
US7647237B2 (en) 1998-04-29 2010-01-12 Minimed, Inc. Communication station and software for interfacing with an infusion pump, analyte monitor, analyte meter, or the like
US6175752B1 (en) 1998-04-30 2001-01-16 Therasense, Inc. Analyte monitoring device and methods of use
US6736797B1 (en) 1998-06-19 2004-05-18 Unomedical A/S Subcutaneous infusion set
US6355021B1 (en) 1998-07-14 2002-03-12 Maersk Medical A/S Medical puncturing device
US6554798B1 (en) 1998-08-18 2003-04-29 Medtronic Minimed, Inc. External infusion device with remote programming, bolus estimator and/or vibration alarm capabilities
US6248067B1 (en) 1999-02-05 2001-06-19 Minimed Inc. Analyte sensor and holter-type monitor system and method of using the same
US6558320B1 (en) 2000-01-20 2003-05-06 Medtronic Minimed, Inc. Handheld personal data assistant (PDA) with a medical device and method of using the same
ATE514372T1 (en) 1998-10-08 2011-07-15 Medtronic Minimed Inc LICENSE PLATE MONITORING SYSTEM WITH REMOTE MEASUREMENT
US6248093B1 (en) 1998-10-29 2001-06-19 Minimed Inc. Compact pump drive system
JP3546015B2 (en) 1998-10-29 2004-07-21 メドトロニック ミニメド インコーポレイテッド Compact and economical pump drive system
US7193521B2 (en) 1998-10-29 2007-03-20 Medtronic Minimed, Inc. Method and apparatus for detecting errors, fluid pressure, and occlusions in an ambulatory infusion pump
US6424847B1 (en) * 1999-02-25 2002-07-23 Medtronic Minimed, Inc. Glucose monitor calibration methods
US6426847B1 (en) 1999-04-21 2002-07-30 Seagate Technology Llc Over-molded base plate and method of manufacture of over-molded base plate for a disc drive
US7806886B2 (en) 1999-06-03 2010-10-05 Medtronic Minimed, Inc. Apparatus and method for controlling insulin infusion with state variable feedback
US6453956B2 (en) 1999-11-05 2002-09-24 Medtronic Minimed, Inc. Needle safe transfer guard
US6366021B1 (en) 2000-01-06 2002-04-02 Varian Medical Systems, Inc. Standing wave particle beam accelerator with switchable beam energy
US7003336B2 (en) 2000-02-10 2006-02-21 Medtronic Minimed, Inc. Analyte sensor method of making the same
US6895263B2 (en) 2000-02-23 2005-05-17 Medtronic Minimed, Inc. Real time self-adjusting calibration algorithm
US7890295B2 (en) 2000-02-23 2011-02-15 Medtronic Minimed, Inc. Real time self-adjusting calibration algorithm
US20010041869A1 (en) 2000-03-23 2001-11-15 Causey James D. Control tabs for infusion devices and methods of using the same
JP2004521667A (en) 2000-09-08 2004-07-22 インシュレット コーポレイション Device, system and method for patient infusion
CN1556716A (en) 2001-02-22 2004-12-22 ���Ͽع����޹�˾ Modular infusion device and method
EP1383560B2 (en) 2001-04-06 2023-04-26 F. Hoffmann-La Roche AG Infusion set
US20020071225A1 (en) 2001-04-19 2002-06-13 Minimed Inc. Direct current motor safety circuits for fluid delivery systems
US6544212B2 (en) 2001-07-31 2003-04-08 Roche Diagnostics Corporation Diabetes management system
US7399277B2 (en) 2001-12-27 2008-07-15 Medtronic Minimed, Inc. System for monitoring physiological characteristics
US8010174B2 (en) 2003-08-22 2011-08-30 Dexcom, Inc. Systems and methods for replacing signal artifacts in a glucose sensor data stream
US7041082B2 (en) 2002-02-28 2006-05-09 Smiths Medical Md, Inc. Syringe pump control systems and methods
US6960192B1 (en) 2002-04-23 2005-11-01 Insulet Corporation Transcutaneous fluid delivery system
US7278983B2 (en) 2002-07-24 2007-10-09 Medtronic Minimed, Inc. Physiological monitoring device for controlling a medication infusion device
US20040068230A1 (en) 2002-07-24 2004-04-08 Medtronic Minimed, Inc. System for providing blood glucose measurements to an infusion device
US20040180391A1 (en) 2002-10-11 2004-09-16 Miklos Gratzl Sliver type autonomous biosensors
US7488601B2 (en) 2003-06-20 2009-02-10 Roche Diagnostic Operations, Inc. System and method for determining an abused sensor during analyte measurement
US8275437B2 (en) 2003-08-01 2012-09-25 Dexcom, Inc. Transcutaneous analyte sensor
US7699807B2 (en) 2003-11-10 2010-04-20 Smiths Medical Asd, Inc. Device and method for insertion of a cannula of an infusion device
EP2329763B1 (en) 2003-12-09 2017-06-21 DexCom, Inc. Signal processing for continuous analyte sensor
GB0329161D0 (en) 2003-12-16 2004-01-21 Precisense As Reagant for detecting an analyte
GB0329849D0 (en) 2003-12-23 2004-01-28 Precisense As Fluorometers
US7344500B2 (en) 2004-07-27 2008-03-18 Medtronic Minimed, Inc. Sensing system with auxiliary display
US8313433B2 (en) 2004-08-06 2012-11-20 Medtronic Minimed, Inc. Medical data management system and process
US7468033B2 (en) 2004-09-08 2008-12-23 Medtronic Minimed, Inc. Blood contacting sensor
US7608042B2 (en) * 2004-09-29 2009-10-27 Intellidx, Inc. Blood monitoring system
GB0426822D0 (en) * 2004-12-07 2005-01-12 Precisense As Sensor for detection of glucose
CN101180093B (en) 2005-03-21 2012-07-18 雅培糖尿病护理公司 Method and system for providing integrated medication infusion and analyte monitoring system
WO2006108809A1 (en) 2005-04-13 2006-10-19 Novo Nordisk A/S Medical skin mountable device and system
US8137314B2 (en) 2006-08-23 2012-03-20 Medtronic Minimed, Inc. Infusion medium delivery device and method with compressible or curved reservoir or conduit
US9233203B2 (en) 2005-05-06 2016-01-12 Medtronic Minimed, Inc. Medical needles for damping motion
US20080097291A1 (en) 2006-08-23 2008-04-24 Hanson Ian B Infusion pumps and methods and delivery devices and methods with same
US8277415B2 (en) 2006-08-23 2012-10-02 Medtronic Minimed, Inc. Infusion medium delivery device and method with drive device for driving plunger in reservoir
US7713240B2 (en) 2005-09-13 2010-05-11 Medtronic Minimed, Inc. Modular external infusion device
ATE439155T1 (en) 2005-11-08 2009-08-15 M2 Medical As INFUSION PUMP SYSTEM
EP2329764A3 (en) * 2005-11-10 2011-10-19 Solianis Holding AG Device for determining the glucose level in body tissue
US8114268B2 (en) 2005-12-30 2012-02-14 Medtronic Minimed, Inc. Method and system for remedying sensor malfunctions detected by electrochemical impedance spectroscopy
US7985330B2 (en) 2005-12-30 2011-07-26 Medtronic Minimed, Inc. Method and system for detecting age, hydration, and functional states of sensors using electrochemical impedance spectroscopy
US8114269B2 (en) 2005-12-30 2012-02-14 Medtronic Minimed, Inc. System and method for determining the point of hydration and proper time to apply potential to a glucose sensor
US7942844B2 (en) 2006-04-28 2011-05-17 Medtronic Minimed, Inc. Remote monitoring for networked fluid infusion systems
US7789857B2 (en) 2006-08-23 2010-09-07 Medtronic Minimed, Inc. Infusion medium delivery system, device and method with needle inserter and needle inserter device and method
US7828764B2 (en) 2006-08-23 2010-11-09 Medtronic Minimed, Inc. Systems and methods allowing for reservoir filling and infusion medium delivery
US20080125700A1 (en) 2006-11-29 2008-05-29 Moberg Sheldon B Methods and apparatuses for detecting medical device acceleration, temperature, and humidity conditions
US7946985B2 (en) 2006-12-29 2011-05-24 Medtronic Minimed, Inc. Method and system for providing sensor redundancy
US20080269714A1 (en) 2007-04-25 2008-10-30 Medtronic Minimed, Inc. Closed loop/semi-closed loop therapy modification system
US7963954B2 (en) 2007-04-30 2011-06-21 Medtronic Minimed, Inc. Automated filling systems and methods
US8323250B2 (en) 2007-04-30 2012-12-04 Medtronic Minimed, Inc. Adhesive patch systems and methods
JP2010534085A (en) 2007-07-20 2010-11-04 メディンゴ・リミテッド Hand operated portable injection device
US7682316B2 (en) * 2007-07-23 2010-03-23 Medtronic, Inc. Implantable heart sound sensor with noise cancellation
US20090270705A1 (en) 2008-04-28 2009-10-29 Medtronic Minimed, Inc. Automobile Physiological Monitoring System and Method for Using the Same
DE102008057341B3 (en) 2008-11-14 2009-12-31 Simonswerk, Gesellschaft mit beschränkter Haftung Door hinge for concealed arrangement between door frame and door leaf
US8181849B2 (en) 2008-12-30 2012-05-22 Medtronic Minimed, Inc. Color detection system for detecting reservoir presence and content in device
US8308679B2 (en) 2009-12-30 2012-11-13 Medtronic Minimed, Inc. Alignment systems and methods
US9089292B2 (en) * 2010-03-26 2015-07-28 Medtronic Minimed, Inc. Calibration of glucose monitoring sensor and/or insulin delivery system
US8919180B2 (en) 2010-10-28 2014-12-30 Medtronic Minimed, Inc. Determination and application of glucose sensor reliability indicator and/or metric
CN102368589B (en) * 2011-11-01 2013-01-02 中国科学院光电技术研究所 Method for stabilizing random drift of pulse laser beam
JPWO2013084416A1 (en) 2011-12-05 2015-04-27 富士電機株式会社 Power converter
US10881339B2 (en) * 2012-06-29 2021-01-05 Dexcom, Inc. Use of sensor redundancy to detect sensor failures
US9649059B2 (en) 2013-12-16 2017-05-16 Medtronic Minimed, Inc. Methods and systems for improving the reliability of orthogonally redundant sensors

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090030293A1 (en) * 2005-02-11 2009-01-29 The University Court Of The University Of Glasgow Sensing device, apparatus and system, and method for operating the same
US20080004536A1 (en) * 2006-06-30 2008-01-03 Baxi Amit S Method and apparatus for amplifying multiple signals using a single multiplexed amplifier channel with software controlled AC response
US20090033482A1 (en) * 2007-07-31 2009-02-05 Abbott Diabetes Care, Inc. Method and apparatus for providing data processing and control in a medical communication system
US20090163855A1 (en) * 2007-12-24 2009-06-25 Medtronic Minimed, Inc. Infusion system with adaptive user interface
US20110319734A1 (en) * 2010-06-23 2011-12-29 Medtronic Minimed, Inc. Sensor systems having multiple probes and electrode arrays
US20120262298A1 (en) * 2011-04-15 2012-10-18 Dexcom, Inc. Advanced analyte sensor calibration and error detection
US20130060105A1 (en) * 2011-09-06 2013-03-07 Medtronic Minimed, Inc. Orthogonally Redundant Sensor Systems and Methods
WO2013184416A2 (en) * 2012-06-08 2013-12-12 Medtronic Minimed, Inc. Application of electrochemical impedance spectroscopy in sensor systems, devices, and related methods

Also Published As

Publication number Publication date
CA3111452A1 (en) 2015-06-25
US10952651B2 (en) 2021-03-23
CA2931955A1 (en) 2015-06-25
US20150164389A1 (en) 2015-06-18
AU2019226130B2 (en) 2021-01-21
JP6717997B2 (en) 2020-07-08
US9943256B2 (en) 2018-04-17
CN109984755A (en) 2019-07-09
US11766195B2 (en) 2023-09-26
US9649058B2 (en) 2017-05-16
US20150164388A1 (en) 2015-06-18
EP3082597A2 (en) 2016-10-26
US20220354394A1 (en) 2022-11-10
US20150164385A1 (en) 2015-06-18
CN106028932B (en) 2019-04-09
JP6339204B2 (en) 2018-06-06
KR20160098487A (en) 2016-08-18
AU2014367039A2 (en) 2016-09-22
CA2931955C (en) 2021-04-27
US20170150911A1 (en) 2017-06-01
AU2014367039A1 (en) 2016-06-16
AU2014367039B2 (en) 2019-06-06
CN109984754A (en) 2019-07-09
US20190357820A1 (en) 2019-11-28
JP6502552B2 (en) 2019-04-17
US20170209082A1 (en) 2017-07-27
AU2019226130A1 (en) 2019-09-26
US20190167170A1 (en) 2019-06-06
US20150164383A1 (en) 2015-06-18
US20190343434A1 (en) 2019-11-14
US10039479B2 (en) 2018-08-07
CN109984753B (en) 2022-06-03
JP2019115714A (en) 2019-07-18
US11382538B2 (en) 2022-07-12
US20180184951A1 (en) 2018-07-05
CN109984753A (en) 2019-07-09
JP2018149327A (en) 2018-09-27
US9649059B2 (en) 2017-05-16
US10258264B2 (en) 2019-04-16
US11406295B2 (en) 2022-08-09
US9603561B2 (en) 2017-03-28
WO2015094576A2 (en) 2015-06-25
KR102250989B1 (en) 2021-05-12
JP2017500942A (en) 2017-01-12
EP3733065B1 (en) 2022-08-31
US20210386335A1 (en) 2021-12-16
EP3082597B1 (en) 2020-07-29
US11103164B2 (en) 2021-08-31
US20150164384A1 (en) 2015-06-18
EP3733065A1 (en) 2020-11-04
US20170209080A1 (en) 2017-07-27
US10426385B2 (en) 2019-10-01
US20210161439A1 (en) 2021-06-03
CN106028932A (en) 2016-10-12

Similar Documents

Publication Publication Date Title
WO2015094576A3 (en) Methods and systems for improving the reliability of orthogonally redundant glucose sensors
EP3775789A4 (en) Detecting errors in sensor data
EP4253536A3 (en) Diffusion resistance layer for analyte sensors
WO2014195076A3 (en) Measuring instrument
EP3713111A3 (en) Integrated wavelength locker
WO2013151692A3 (en) Method and system for identifying an erroneous speed or wheel size of a vehicle
GB201320077D0 (en) Laser tracker that combines two different wavelengths with a fiber-optic coupler
GB201106065D0 (en) Sensor readout with redundancy-checking
BR112015022763A8 (en) sensor to detect an analyte
GB201101305D0 (en) Gnns performance enchancement using accelerometer-only data
BR112015002095A2 (en) systems and methods for inspecting and monitoring a pipe
JP2016528480A5 (en)
WO2009015211A3 (en) Systems and methods for antenna calibration
EA201991529A1 (en) SYSTEMS AND METHODS FOR CALIBRATION, VERIFICATION AND SENSITIVITY CHECK OF SENSORS
WO2008073454A3 (en) Multiple-degree of freedom interferometer with compensation for gas effects
WO2017030648A3 (en) Systems and methods for determining shape and/or position
IL195104A (en) Device and method for combining samples from an inertial measurement sensor cluster
WO2008144114A3 (en) System and technique to remove perturbation noise from seismic sensor data
WO2014036367A3 (en) Navigation system and method
RU2013127127A (en) DELAY COMPENSATION
WO2019060348A3 (en) Solid state image sensor with on-chip filter and extended spectral response
BR112014005130A2 (en) method and system for sensor recalibration
EP3878359A4 (en) Biological electrode, biological sensor, and biological signal measurement system
WO2007111978A3 (en) Inertial measurement system and method with bias cancellation
WO2014096973A3 (en) Systems and methods for internal analyte sensing

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 14816501

Country of ref document: EP

Kind code of ref document: A2

ENP Entry into the national phase

Ref document number: 2931955

Country of ref document: CA

ENP Entry into the national phase

Ref document number: 2016539982

Country of ref document: JP

Kind code of ref document: A

ENP Entry into the national phase

Ref document number: 2014367039

Country of ref document: AU

Date of ref document: 20141121

Kind code of ref document: A

NENP Non-entry into the national phase

Ref country code: DE

REEP Request for entry into the european phase

Ref document number: 2014816501

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2014816501

Country of ref document: EP

ENP Entry into the national phase

Ref document number: 20167019352

Country of ref document: KR

Kind code of ref document: A