An adenovirus wherein at least one portion of at least one loop region of the hexon is changed. In one embodiment, the adenovirus, prior to modification, is of a first serotype, and at least a portion of at least one loop region of the hexon is removed and replaced with at least a portion of at least...http://www.google.es/patents/US5922315?utm_source=gb-gplus-sharePatente US5922315 - Adenoviruses having altered hexon proteins