Presented are ways to address the problem of replication competent adenovirus in adenoviral production for use with, for example, gene therapy. Packaging cells having no overlapping sequences with a selected vector and are suited for large scale production of recombinant adenoviruses. A system for use...http://www.google.es/patents/US6602706?utm_source=gb-gplus-sharePatente US6602706 - Packaging systems for human recombinant adenovirus to be used in gene therapy
Packaging systems for human recombinant adenovirus to be used in gene therapy