Prostate stem cell antigen (PSCA) is expressed in the majority of prostate cancer patients, making it an ideal target for cancer immunotherapy. Murine monoclonal antibody 1G8 binds to PSCA with nanomolar affinity, but its efficacy as a therapeutic agent is limited by the generation of a HAMA response....http://www.google.es/patents/US8088908?utm_source=gb-gplus-sharePatente US8088908 - Humanized anti-prostate stem cell antigen monoclonal antibody
