The present invention relates to a method of stimulating the proliferation and appropriate cell maturation of a variety of different cells and tissues in three-dimensional cultures in vitro using TGF-.beta. in the culture medium. In accordance with the invention, stromal cells, including, but not limited...http://www.google.es/patents/US5962325?utm_source=gb-gplus-sharePatente US5962325 - Three-dimensional stromal tissue cultures