Anti-ulcer compositions are disclosed having therapeutic agents dispersed in a soluble matrix formed by melt spinning the therapeutic agent with a carrier and hydrogel. Methods of treating ulcer-bearing tissue and preparing the matrix are also disclosed. One embodiment includes use of gastric irritating...http://www.google.es/patents/US5651987?utm_source=gb-gplus-sharePatente US5651987 - Ulcer prevention and treatment composition