A rate-responsive cardiac pacemaker comprising a minute ventilation circuit and an activity circuit. The minute ventilation circuit computes a first target pacing rate as a function of measurements of the patient's pleural blood impedance, and the activity circuit computes a second target pacing rate...http://www.google.es/patents/US5271395?utm_source=gb-gplus-sharePatente US5271395 - Method and apparatus for rate-responsive cardiac pacing
Method and apparatus for rate-responsive cardiac pacing