A modified interferon beta (INFβ) is provided, which is less immunogenic than human INFβ (SEQ ID NO: 1) when administered to a human in vivo. The modified INFβ comprises an amino acid residue sequence that differs from SEQ ID NO: 1 by a substitution at one or more residues of SEQ ID NO: 1. Preferred...http://www.google.es/patents/US7381795?utm_source=gb-gplus-sharePatente US7381795 - Modified interferon beta with reduced immunogenicity
Modified interferon beta with reduced immunogenicity