A once-a-day controlled release drug delivery system of diltiazem hydrochloride is provided, which is bioequivalent in plasma profile of Cardizem CD. The fast, medium, and slow release fractions are prepared using various compositions and weight gains. The individual fill weights are computed and then...http://www.google.es/patents/US6635277?utm_source=gb-gplus-sharePatente US6635277 - Composition for pulsatile delivery of diltiazem and process of manufacture
Composition for pulsatile delivery of diltiazem and process of manufacture
