Disclosed are methods of producing a synthetic oligonucleotide of selected nucleotide sequence which is internally functionalized at at least one selected location with an aminoalkyl-phosphoramidate and labelled with a nonradioactive material. Also disclosed are oligonucleotides produced by this met...http://www.google.es/patents/US5563253?utm_source=gb-gplus-sharePatente US5563253 - Linear aminoalkylphosphoramidate oligonucleotide derivatives
Linear aminoalkylphosphoramidate oligonucleotide derivatives