A master mould is made by wire cutting a plate in two or more directions to provide a base with an array of master mould needles protruding therefrom. The size and shape of the master mould needles can readily be varied by varying the angles of upward and downward cuts in the two or more directions....http://www.google.es/patents/US7497980?utm_source=gb-gplus-sharePatente US7497980 - Microneedles and microneedle fabrication