The present invention relates to methods of enzymatically synthesizing oligonucleotides. In particular, it relates to the use of 3'-ribonucleotide primers which effectively serve to initiate oligonucleotide synthesis, and can also be easily cleaved from synthesis products and reused in subsequent synthesis...http://www.google.es/patents/US5916777?utm_source=gb-gplus-sharePatente US5916777 - Enzymatic synthesis of oligonucleotides using 3'-ribonucleotide primers
Enzymatic synthesis of oligonucleotides using 3'-ribonucleotide primers