A biosensor for the detection and determination of the concentration of toxins by use of enzyme inhibition. Inhibition biosensors are affected by non-specific denaturation and substrate utilization which both result in a limited operational lifetime. These problems are mitigated by providing in an environment...http://www.google.es/patents/US5496452?utm_source=gb-gplus-sharePatente US5496452 - Substrate regenerating biosensor