The efficacy of amide- and ester-linked local anesthetics is increased by administering methanesulfonamide compounds (for example, ibutilide and sotalol) as adjuvants with the local anesthetics. The effectiveness of these compounds as adjuvants is further increased by the concomitant administration of...http://www.google.es/patents/US20020161018?utm_source=gb-gplus-sharePatente US20020161018 - Enhancement of the potency and efficacy of local anesthetics with ibutilide and other methanesulfonamide drugs
Enhancement of the potency and efficacy of local anesthetics with ibutilide ...
