There are disclosed apparatus and methods for performing in-vivo measurements of enzyme kinetics on the epidermis and mucous membranes of a subject. One or more reactants are placed on a predetermined area of the skin in order to react with the enzyme or other biological substance of interest. At least...http://www.google.es/patents/US4071020?utm_source=gb-gplus-sharePatente US4071020 - Apparatus and methods for performing in-vivo measurements of enzyme activity
Apparatus and methods for performing in-vivo measurements of enzyme activity