Provided are antineoplastic derivatives by a process of selective halogenation of side chains of unsaturated taxanes; more particularly, the process involves the use of halogens, particularly bromine, which is easily added to the side chain double bond of cephalomannine, leaving paclitaxel...http://www.google.es/patents/US5840748?utm_source=gb-gplus-sharePatente US5840748 - Dihalocephalomannine and methods of use therefor
