In vivo assays for selecting candidate therapeutics for inhibiting amyloidoses, such as congophilic and fibrillar /A4 amyloid deposition in brain. A candidate reagent is administered to a first rat in a first infusate comprising /A4 peptide and perlecan by continuous infusion for at least one week into...http://www.google.es/patents/US6340783?utm_source=gb-gplus-sharePatente US6340783 - Rodent models of human amyloidoses