Photoaging of undamaged skin due to UVB irradiation exposure is inhibited by administering an agent that inhibits (1) the activity of UVB irradiation inducible MMPs in the skin, (2) one or both of the transcription factors AP-1 and NF-.kappa.B or (3) at least one of the GTP binding...http://www.google.es/patents/US5837224?utm_source=gb-gplus-sharePatente US5837224 - Method of inhibiting photoaging of skin