The present invention provides a method for identifying a thermostable polymerase having altered fidelity. The method consists of generating a random population of polymerase mutants by mutating at least one amino acid residue of a thermostable polymerase and screening the population for one or more...http://www.google.es/patents/US7312059?utm_source=gb-gplus-sharePatente US7312059 - Thermostable polymerases having altered fidelity and methods of identifying and using same
Thermostable polymerases having altered fidelity and methods of identifying ...