Antigenic epitopes associated with the extracellular segment of the domain which anchors immunoglobulins to the B cell membrane are disclosed. For IgE, the epitopes are present on IgE-bearing B cells but not basophils or the secreted, soluble form of IgE. DNA constructs encoding chimeric antibodies,...http://www.google.es/patents/US5231026?utm_source=gb-gplus-sharePatente US5231026 - DNA encoding murine-human chimeric antibodies specific for antigenic epitopes of IgE present on the extracellular segment of the membrane domain of membrane-bound IgE
DNA encoding murine-human chimeric antibodies specific for antigenic ...
