(i9) United States
(12) Patent Application Publication
Myung et al.
(54) INTERPENETRATING POLYMER
NETWORK HYDROGEL CONTACT LENSES
(76) Inventors: David Myung, Mountain View, CA (US); Jaan Noolandi, Palo Alto, CA (US); Christopher Ta, Saratoga, CA (US); Curtis W. Frank, Cupertino, CA (US)
LUMEN INTELLECTUAL PROPERTY
2345 YALE STREET, 2ND FLOOR
PALO ALTO, CA 94306 (US)
(21) Appl. No.: 11/636,114
(22) Filed: Dec. 7, 2006
Related U.S. Application Data
(63) Continuation-in-part of application No. 11/243,952, filed on Oct. 4, 2005.
Continuation-in-part of application No. 11/409,218, filed on Apr. 20, 2006, and which is a continuationin-part of application No. 11/243,952, filed on Oct. 4, 2005.
(60) Provisional application No. 60/843,942, filed on Sep. 11, 2006. Provisional application No. 60/783,307, filed on Mar. 17, 2006. Provisional application No.
60/616,262, filed on Oct. 5, 2004. Provisional application No. 60/673,172, filed on Apr. 20, 2005. Provisional application No. 60/673,600, filed on Apr. 21, 2005. Provisional application No. 60/616,262, filed on Oct. 5, 2004. Provisional application No. 60/673, 172, filed on Apr. 20, 2005.
(51) Int. CI.
G02C 7/04 (2006.01)
(52) U.S. CI 351/160 R
The present invention provides interpenetrating polymer network hydrogels that have high oxygen permeability, strength, water content, and resistance to protein adsorption. The hydrogels include two interpenetrating polymer networks. The first polymer network is based on a hydrophilic telechelic macromonomer. The second polymer network is based on a hydrophilic monomer. The hydrophilic monomer is polymerized and cross-linked to form the second polymer network in the presence of the first polymer network. The telechelic macromonomer preferably has a molecular weight of between about 575 Da and about 20,000 Da. Mixtures of molecular weights may also be used. In a preferred embodiment, the hydrophilic telechelic macromonomer is PEGdiacrylate or PEG-dimethacrylate and the hydrophilic monomer is an acrylic-based monomer. The material is designed to serve as a contact lens.