Glycemic control monitoring using implantable medical device

(52) (58)

(56)

Prior Publication Data

US 2009/0048503 Al Feb. 19, 2009

Int. CI.

A61B 5/02 (2006.01)
A61B 5/00 (2006.01)
A61N1/00 (2006.01)

U.S. CI 600/365; 600/528; 607/22

Field of Classification Search 600/365,

600/513, 528; 607/3, 6, 19, 22, 32, 60, 62 See application file for complete search history.

References Cited

U.S. PATENT DOCUMENTS

(Continued)

OTHER PUBLICATIONS

Schwingshandl, et al., "Echocardiographic Load-Independent Indices of Contractility in Children and Adolescents with Type I Diabetes: Effect of Metabolic Control and Insulin on Left Ventricular Performance", Pediatric Cardiology, vol. 16, No. l,pp. 1-5 (Abstract only) Jan. 1995, 1 page.

Primary Examiner—Charles A Marmor, II

Assistant Examiner—Christian Y Jang

(74) Attorney, Agent, or Firm—Pauly, DeVries, Smith &

Deffner, L.L.C.

An apparatus for monitoring a patient's blood glucose level. The apparatus includes an implantable medical device having a controller and an implantable heart sounds sensor configured to transmit signals to the controller of the implantable medical device. The controller is configured to determine if a patient is hypoglycemic or hyperglycemic based on the signals from the heart sounds sensor. A method is also disclosed that includes sensing the patient's heart sounds, determining the amplitude of the S2 heart sound, determining the length of the interval from the S1 heart sound to the S2max heart sound, determining the length of the interval from the S1 heart sound to the S2e„rf heart sound, and determining the patient's blood glucose status based on the patient's heart sounds.

20 Claims, 8 Drawing Sheets