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US005530074A

United States Patent [19] [ii] Patent Number: 5,530,074

Jarrett et al. [45] Date of Patent: Jun. 25, 1996

[54] COATING FOR TISSUE DRAG REDUCTION

[75] Inventors: Peter K. Jarrett, New Haven; George Jessup, Brookfield; Louis Rosati, Norwalk, all of Conn.; Chris Martin, Guildford, Australia; John W. Maney, Spring Valley, N.Y.

[73] Assignee: American Cyanamid Company,
Wayne, N.J.

[21] Appl. No.: 473,825
[22] Filed: Jun. 7,1995

Related U.S. Application Data

[62] Division of Ser. No. 230,267, Apr. 20, 1994, Pat. No. 5,442,016, which is a division of Ser. No. 843,053, Mar. 16, 1992, Pat. No. 5,352,575.

[51] Int. CI.6 C08L 67/04; C08G 63/08;

B32B 27/02; A61L 17/00

[52] U.S. CI 525/415; 128/898; 427/532;

428/357; 428/394; 428/395; 428/480; 525/408; 525/411; 528/354; 528/361; 606/230; 606/231

[58] Field of Search 428/357, 394,

428/395, 480; 525/408, 411, 415; 528/354, 361; 606/230, 231; 128/898; 427/532

[56] References Cited

U.S. PATENT DOCUMENTS

4,027,676 6/1977 Mattei 128/335.5

4,043,344 8/1977 Landi et al 128/335.5

4,047,533 9/1977 Perciaccante et al 128/335.5

4,201,216 5/1980 Mattei 128/335.5

4,438,253 3/1984 Casey et al 528/86

4,452,973 6/1984 Casey et al 528/354

4,459,317 7/1984 Lambert 427/2

4,487,808 12/1984 Lambert 428/423.1

4,526,938 7/1985 Churchill et al 525/415

4,624,256 11/1986 Messier et al 128/335.5

4,649,920 3/1987 Rhum 128/335.5

4,705,820 11/1987 Wang et al 524/381

4,716,203 12/1987 Casey et al 525/408

4,788,979 12/1988 Jarrett et al 128/335.5

4,791,929 12/1988 Jarrett et al 128/335.5

4,826,945 5/1989 Cohn et al 528/76

4,857,602 8/1989 Casey et al 525/408

4,942,035 7/1990 Churchill et al 424/423

4,994,074 2/1991 Bezwada et al 606/230

5,066,772 11/1991 Tang et al 528/354

5,076,807 12/1991 Bezwada et al 606/230

5,123,912 6/1992 Kaplan et al 606/230

5,352,515 10/1994 Jarrett et al 428/357

5,442,016 8/1995 Jarrett et al 525/415

FOREIGN PATENT DOCUMENTS

0014238 8/1980 European Pat. Off. A61K 9/02

0411545 2/1991 European Pat. Off. A91L 17/100

0436308 7/1991 European Pat. Off A61L 17/100

1248513 10/1971 United Kingdom D06M 15/36

OTHER PUBLICATIONS

Synthesis and Characterization of Poly(Oxytheylene)-poly-E-caprolactone Block Copolymers, Perret et al., Chemical Abstract, vol. 70, 78623x (1969).

Primary Examiner—Shelley A. Dodson

Attorney, Agent, or Firm—Montgomery W. Smith; Ari M.

Bai; Rita D. Vacca

[57] ABSTRACT

This invention relates to materials for medical or veterinary use that possess considerably improved properties with regard to friction. The invention also relates to the production of such materials from existing materials that possess suitable bulk properties, but inappropriate frictional properties. This invention also relates to a hydrophilic coating material that provides improved frictional properties.

3 Claims, 6 Drawing Sheets

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COMPARISON TEST FOR FIG. 5 OF COATED POLYBUTESTER

NONCOATED POLYPROPYLENE OF EXAMPLE IN

/ TISSUE DRAG TEST \ / TISSUE DRAG TEST \

V OF EXAMPLE 5 J \ OF EXAMPLE 5 )

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