United States Patent  [ii] Patent Number: 4,610,847
Hood et al.  Date of Patent: Sep. 9,1986
 CONVERSION FLASK FOR SEQUENTIAL PERFORMANCE APPARATUS
 Inventors: Leroy E. Hood, Pasadena; Michael W. Hunkapiller, San Gabriel; William J. Dreyer, Pasadena; Rodney M. Hewick, Pasadena; Anton W. Stark, Pasadena, all of Calif.
 Assignee: California Institute of Technology, Pasadena, Calif.
 Appl. No.: 602,699
 Filed: Apr. 23, 1984
Related U.S. Application Data
 Division of Ser. No. 380,109, May 20, 1982, which is a division of Ser. No. 190,100, Sep. 23, 1980, abandoned.
 Int. CI.4 B01J 19/26; G01N 33/68
 U.S. CI 422/102; 261/124;
422/68; 422/231; 436/89
 Field of Search 422/102, 231, 68;
261/124; 239/524, 267; 436/89, 174
 References Cited
U.S. PATENT DOCUMENTS
3,959,307 5/1976 Wittmann-Liebold et al. .
4,065,412 12/1977 Dreyer .
4,134,514 1/1979 Shumacher et al 261/124 X
4,227,886 10/1980 Bullock et al 422/64 X
Wittmann-Liebold et al(II), Analytical Biochemistry,
vol. 75, pp. 621-633, 1976, "A Device Coupled to a
Modified Sequenator for the Automated Conversion of
Anilinothiazolinones into PTH Amino Acids".
Primary Examiner—Arnold Turk
Attorney, Agent, or Firm—Joseph E. Mueth
Conversion flask for use is an apparatus for the sequential performance of chemical processes on a sample of chemical material. The flask includes at least three capillary tubes and a large bore tube extending into the interior thereof for the introduction and withdrawal of various fluids. The capillary tubes are constructed to introduce a plurality of fine bubbles into a liquid within the flask to agitate the liquid and accelerate drying, to impinge chemicals on the walls of the flask, and to produce a spray onto the interior walls of the flask in proximity to its upper end to wash down the interior walls of the flask.
1,532,233 4/1925 Dahlberg et al. 1,595,626 8/1926 Gunther et al.
6 Claims, 27 Drawing Figures