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Prior Publication Data

US 2005/0137630 Al Jun. 23, 2005

Int. CI.

A61N1/00 (2006.01)

U.S. CI 607/9

Field of Classification Search 607/5,

607/9,26; 600/515 See application file for complete search history.

References Cited

U.S. PATENT DOCUMENTS

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4,972,834 5,052,388 5,174,289 5,190,035 5,267,560 5,331,966 5,403,356

11/1990 10/1991 12/1992 3/1993 12/1993 7/1994 4/1995

Begemann et al.
Sivula et al.
Cohen
Salo et al.
Cohen

Bennett et al.
Hill et al.

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OTHER PUBLICATIONS

Auricchio, Angelo , "Effect of pacing chamber and atrioventricular delay on acute systolic function of paced patients with congestive heart failure. The Pacing Therapies for Congestive Heart Failure Study Group. The Guidant Congestive Heart Failure Research Group", Circulation, 99(23), (Jun. 15, 1999),2993-3001.

(Continued)

Primary Examiner—George Manuel

(74) Attorney, Agent, or Firm—Schwegman, Lundberg,

Woessner, & Kluth, PA.

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A method or system for computing and/or setting optimal cardiac resynchronization pacing parameters as derived from intrinsic conduction data is presented. The intrinsic conduction data includes intrinsic atrio-ventricular and interventricular delay intervals which may be collected via the sensing channels of an implantable cardiac device. Among the parameters which may be optimized in this manner are an atrio-ventricular delay interval and a biventricular offset interval. In one of its aspects, the invention provides for computing optimum pacing parameters for patients having some degree of AV block or with atrial conduction deficits. Another aspect of the invention relates to a pacing mode and configuration for providing cardiac resynchronization therapy to patients with a right ventricular conduction disorder.

9 Claims, 3 Drawing Sheets

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2005/0137634 Al 6/2005 Hall et al. 2006/0047320 Al 3/2006 Ding et al.

OTHER PUBLICATIONS

Cazeau, S , et al., "Four chamber pacing in dilated cardiomyopathy", Pacing and clinical electrophysiology : PACE, 17(11 Pt 2), (Nov. 1994), 1974-9.

Cochlain, et al., "The Effects of the Interval Between Right and Left
Ventricular Activation on Sychronization in Patients with
Bi-ventricular Pacemakers", Pacing and clinical
electrophysiology :PACE, 23(11), (Apr. 2000),576.
Daubert, Claude , "Permanent dual atrium pacing in major
interatrial conduction blocks: a four years experience (Abstract
141)", Pacing and clinical electrophysiology : PACE, 3(Part II),
NASPE Abstracts—Abstract 141,(Apr. 1993),885.
Daubert, L. C, "Permanent Left Ventricular Pacing With
Transvenous Leads Inserted Into the Coronary Veins", Pacing and
Clinical Electrophysiology : PACE, 21, (Jan. 1998),239-245.
Daubert, Claude , "Renewal of permanent left atrial pacing via the
coronary sinus", Pacing and clinical electrophysiology: PACE,
25(Part II), NASPE Abstracts—Abstract 255,(Apr. 1992),572.
Durrer, Dirk, et al., "Total excitation of the isolated human heart.",
Circulation, 41(6), (Jun. 1970),889-912.

Lieberman, Randy , et al., "Relationship Between Electrical and
Hemodynamic Parameters Using Bi-Ventricular and Uni-
Ventricular Pacing in Heart Failure Patients", Journal of the Ameri-
can College of Cardiology, (Feb. 2001), 155A.
Hall, J. A., "Biatrial Pacing Optimization for Biventricular Pacing",
U.S. Appl. No. 10/920,698, filed Aug. 18, 2004, 22 pgs.

* cited by examiner

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