This invention concerns a family of chimeric antibodies with high affinities to a high molecular weight, tumor-associated sialylated glycoprotein antigen (TAG-72) of human origin. These antibodies have (1) high affinity animal V.sub.H and V.sub.L sequences which mediate TAG-72 binding and (2) human C.sub.H...http://www.google.es/patents/US6051225?utm_source=gb-gplus-sharePatente US6051225 - Family of high affinity, modified antibodies for cancer treatment
Family of high affinity, modified antibodies for cancer treatment